📄 medicine

Paramedics and Emergency Medical Technicians’ Perspectives on Innovation in Prehospital Trauma Care: A Qualitative Study in Saudi Arabia

This qualitative study of Saudi ambulance clinicians reveals that while they view innovation as a practical means to improve prehospital trauma care and identify specific barriers and facilitators, realizing their potential as contributors requires transparent submission mechanisms, structured training, and supportive leadership to transform frontline ideas into evaluated solutions.

Naif Harthi, Fayez Mutairan Alanazi, Layan S. Al-Subaie, Shujaa D. Alyami, Amera Alrasheedi, Ziyad Darraj, Mohmmad A. Al (…)2026-07-07
📄 medicine

Intimate partner violence during pregnancy and risk of stillbirth, low birth weight, and early neonatal mortality: a pooled design-corrected analysis of 40 low- and middle-income countries

This pooled analysis of 40 low- and middle-income countries reveals that intimate partner violence during pregnancy is significantly associated with an increased risk of stillbirth, though not with low birth weight or early neonatal mortality, underscoring the need for design-aware inference and routine IPV screening in antenatal care.

Xiaoyu Wu, Benqing Zheng2026-07-07
📄 medicine

Anterolateral Retrograde Access in Chronic Total Femoropopliteal Occlusions: A Safe and Effective Alternative Approach

This retrospective study of 66 patients demonstrates that the anterolateral retrograde puncture approach is a safe and highly effective alternative for revascularizing femoropopliteal chronic total occlusions following failed antegrade intervention, achieving a 98.5% technical success rate with no major complications.

Burcu Özyazgan, Fatih Yılmaz, Filiz Kızılırmak Yılmaz, Ayhan Küp, Dursun Akaslan, Erkan Köklü, Can Özkan2026-07-07
📄 medicine

Epidemiological Criminological and Medico Legal Characteristics of Assaults and Bodily Injuries in Guinea Over a Twelve Year Period

This retrospective study of 19,050 medico-legal cases in Guinea from 2012 to 2024 reveals that assaults predominantly affect young adult males through intentional acts in public or domestic settings, underscoring the critical role of forensic medicine in judicial processes while highlighting the need for standardized prevention strategies.

Namandian TRAORÉ, Thierno Mamadou Cherif DIALLO, Ousmane CAMARA, Ousmane SOUMAH, Sia Marie OUENDENO, Djenabou BAH, Sambo (…)2026-07-07
📄 medicine

Interpretable Machine Learning for Preoperative Survival Prediction in Resected Brain Metastases: A Real-World Cohort Study with SHAP-Based Feature Attribution

This study demonstrates that interpretable machine learning models, particularly Random Forest and Logistic Regression, can effectively predict 6- and 12-month survival in patients with resected brain metastases by integrating diverse preoperative variables, with neutrophil-to-lymphocyte ratio, age, and tumor volume identified as the most consistent prognostic factors.

David Wasilewski, Martin Misch, Julia Onken, Peter Vajkoczy, Anton Früh2026-07-07
📄 medicine

A Non-invasive Nomogram for High-Risk Esophageal Varices in Cirrhosis without Transient Elastography: Development and Internal Validation

This study developed and internally validated a simple, non-invasive nomogram using routine clinical and ultrasonographic parameters (gender, hemoglobin, platelet count, right liver thickness, portal vein diameter, and spleen diameter) to effectively stratify the risk of high-risk esophageal varices in cirrhotic patients, offering a cost-effective alternative to transient elastography and endoscopy.

Yi Wu, Junyang Luo, Shuixian Yang, Shuaishuai Kong, Dan Dan Chen, Wenhui Guo, Nianfeng Fan, Zebin Wu, Yurong Gu, Zhaoxia (…)2026-07-07
📄 medicine

Tailored Personas for Self-Management in Young and Middle-Aged Patients with Systemic Lupus Erythematosus: A Qualitative Study

This qualitative study identifies five distinct patient personas among young and middle-aged systemic lupus erythematosus (SLE) patients based on their unique self-management characteristics, barriers, and needs, providing a theoretical foundation for developing tailored intervention strategies to improve disease control and quality of life.

Jiaying Chen, Long Zhang, Zhaorong Huang, Liuyuan Zhang, Yi He, Erwei Sun, Jiali Chen2026-07-07
📄 medicine

Online risk calculator and nomogram prediction model for lymphocele after radical prostatectomy combined with pelvic lymph node dissection

This study developed and validated a nomogram-based online risk calculator that effectively predicts the likelihood of lymphocele formation following radical prostatectomy with pelvic lymph node dissection by identifying key independent risk factors such as the extent of lymph node dissection, drainage duration, and dynamic skin assessment scores.

Hanjing Zhu, Juan Xie, Chenfei Chi, Sijie You, Yinjie Zhu2026-07-07
📄 medicine

Light Chain Neurofilament to HDGFL2 cryptic peptide ratio as a fluid biomarker to monitor TDP-43 dysfunction in ALS and FTD

This study demonstrates that the ratio of light chain neurofilament (NfL) to HDGFL2 cryptic peptide in cerebrospinal fluid serves as a highly specific biomarker for monitoring TDP-43 dysfunction and improving diagnostic accuracy in ALS and FTD patients.

Irene Santos-García, Katherine Irwin, Patricia Garay-Albizuri, Juan Pablo Garcés, Fermin Moreno-Izco, Javier Ruiz-Martin (…)2026-07-07