4814 papers
This real-world study demonstrates that combining pulsed-field ablation for atrial fibrillation with left atrial appendage occlusion in a single session is feasible and safe, yielding low rates of peri-device leaks and complications while significantly reducing overall healthcare utilization compared to performing the procedures separately.
This prospective observational study of 2,017 pregnant women reveals that while gestational diabetes mellitus is associated with higher rates of urinary infection markers, even within the non-diabetic population, elevated fasting plasma glucose levels independently predict increased risks of positive urine cultures, Group B Streptococcus colonization, and asymptomatic bacteriuria, suggesting that glycemic risk should be viewed as a continuous spectrum rather than a categorical threshold.
In a nationwide retrospective cohort of 675 Uruguayan patients under 50 with metastatic colorectal cancer, elevated CA 19-9 levels at diagnosis were independently associated with significantly shorter overall survival, establishing its potential as a low-cost prognostic tool for risk stratification in resource-constrained settings.
This real-world study utilizing U.S. claims data reveals that pregnant women with generalized myasthenia gravis face significantly higher risks of adverse pregnancy outcomes and disease crises while receiving fewer treatments and incurring higher overall healthcare costs compared to their non-pregnant or non-disease counterparts.
This case report highlights the importance of distinguishing true from "false" transvalvular gradients caused by hyperdynamic states following TAVR by incorporating flow-dependent parameters like stroke volume to guide accurate diagnosis and management.
This qualitative study of 39 Australian healthcare workers reveals that language barriers, diverse cultural norms, and poor health system literacy are the primary challenges in delivering emergency care to racial and ethnic minority patients, highlighting the urgent need for improved formal interpretation services and co-designed health literacy education to ensure safe, culturally sensitive care.
This pilot study demonstrates that a spaced retraining intervention two months after initial cardiac POCUS training helps maintain medium-term skill retention among residents, with those possessing intermediate pre-training competency levels deriving the most benefit compared to beginners who require additional support.
Using data from the 2022 Ghana Demographic and Health Survey, this study identifies maternal education, household wealth, antenatal care attendance, and marital status as significant socioeconomic and regional determinants of complete childhood immunization among children aged 12–59 months in Ghana, highlighting the need for equity-focused interventions to improve vaccination coverage.
This prospective observational study demonstrates that cerebral myo-inositol levels, measured via magnetic resonance spectroscopy, exhibit a time-dependent trajectory of elevation in the acute–subacute phase followed by normalization in the chronic phase after spinal cord injury, reflecting the biphasic plasticity of reactive astrocytes and supporting MI-MRS as a non-invasive biomarker for monitoring astrocyte dynamics.
This study in Mettu Woreda, Ethiopia, reveals a significant gap between high insecticide-treated net ownership (82.4%) and lower utilization (58.7%) among pregnant women and children under five, identifying health education, household head's education, and family size as key predictors and recommending a strategic shift from distribution to behavioral change communication to improve malaria control.