4814 papers
This retrospective cohort study of 374 critically ill SFTS patients demonstrates that invasive arterial blood pressure monitoring not only provides more accurate hemodynamic assessment during hypotensive shock but also significantly reduces the incidence and severity of upper limb skin ecchymosis compared to non-invasive monitoring.
This cross-sectional study of Iranian adults with type 2 diabetes reveals that higher educational attainment, greater wealth, health insurance coverage, and non-smoking behavior are independently associated with adherence to healthy dietary patterns.
This mixed-methods study reveals that while individuals with rare diseases report generally positive attitudes and comfort regarding sexuality in surveys, in-depth interviews and biofeedback data expose a significant gap between these self-reported metrics and their actual lived experiences, characterized by a lack of professional dialogue and physiological fluctuations, thereby highlighting the urgent need for targeted interventions to integrate sexuality into their overall well-being.
This study validates the Quality of Patient-Centered Outcomes Research Instrument (QPCOR) as a reliable, psychometrically sound tool for measuring the quality of patient-centered research partnerships, offering a standardized alternative to qualitative evaluations to enhance cross-study comparability and assess relational engagement.
This cross-sectional pilot study of 200 U.S. healthcare workers found that occupational burnout is significantly associated with elevated anxiety, depression, and PTSD symptoms, with perceived sleep quality acting as a moderator that specifically influences the relationship between burnout and depressive symptoms at low to moderate burnout levels.
This mixed-methods study identifies that while existing digital pain self-management tools lack cultural responsiveness for South Asians, co-developing evidence-based, culturally tailored resources that integrate symptom monitoring, psychological support, and social context is essential to effectively engage people with chronic musculoskeletal pain in Pakistan.
This study characterizes the pharmacokinetic profile of the gastrointestinal acute radiation syndrome mitigator YK-4-250 in male and female mice, revealing that while radiation exposure significantly impairs systemic clearance and alters absorption kinetics in a dose- and sex-dependent manner, a higher 40 mg/kg dose effectively equalizes exposure between sexes, suggesting a need for adaptive dosing strategies in radiation-mitigative therapies.
This integrated SEER-TCGA study reveals that sigmoid colon cancer carries a significantly better prognosis than splenic flexure/descending colon cancer due to distinct molecular and immune microenvironmental features, supporting the need to treat left-sided colon cancer as heterogeneous rather than a homogeneous entity.
This multi-component pilot evaluation in rural Ethiopia demonstrates that task-shifting long-acting reversible contraceptive services to Level IV Health Extension Workers is a clinically safe, effective, and highly acceptable strategy for expanding access, though it highlights the need for targeted training and ongoing supervision to address specific knowledge gaps and improve competency in IUCD and Jadelle procedures.
This experimental study on anesthetized beagles demonstrates that peripheral venous pressure (PVP) correlates linearly with central venous pressure (CVP) across a broad range, and that incorporating tissue pressure into an estimation formula significantly improves CVP prediction accuracy, particularly in low-pressure states.