medicine papers | Gist.Science

Maternal Risk Factors and Short-Term Clinical Outcomes of Different Small Vulnerable Newborn (SVN) Phenotypes: A Retrospective Cohort Study of 998 Cases

This retrospective cohort study of 998 high-risk neonates demonstrates that distinct Small Vulnerable Newborn (SVN) phenotypes are driven by unique maternal risk pathways—such as inflammation for preterm/low birth weight infants and placental ischemia for the "Three-in-One" phenotype—and are associated with varying postnatal respiratory outcomes, supporting the need for phenotype-based risk stratification.

Zilong Feng, Xiaohui Cao, Min Jiang, Xiaopei Zhou, Shanyu Jiang, Hengchao Ruan, Xiaokang Deng2026-07-05

📄 medicine

Poor Agreement Between Bioreactance and Echocardiographic Assessment of Fluid Responsiveness During Passive Leg Raising in Patients With Shock: A Prospective Study

This prospective study of 30 critically ill patients with shock found that bioreactance-based monitoring demonstrates poor agreement with transthoracic echocardiography in assessing fluid responsiveness during passive leg raising, indicating that the two methods are not interchangeable for this clinical purpose.

Antonious Anis, Juliann Shih, Vidhani Goel², Kavita Batra, Irene Huang⁴, Mutsumi J. Kioka2026-07-05

📄 medicine

Comparing the Accuracy of Toric Intraocular Lens Calculations Between the IOLMaster 700 and iTrace

In a prospective study of 217 eyes, the IOLMaster 700 demonstrated slightly superior accuracy compared to the iTrace in predicting postoperative astigmatism following toric intraocular lens implantation, particularly in the against-the-rule subgroup.

Andi Superceanu, Matt Holzer, Christoph Richard, Hermina Strungaru2026-07-05

📄 medicine

Associations of C-reactive protein-triglyceride-glucose index and Cholesterol- high-density lipoprotein-glucose index with heart disease risk in individuals with cardiovascular-kidney-metabolic syndrome stages 0-3: a cohort study from CHARLS

This cohort study of 6,740 individuals with cardiovascular-kidney-metabolic syndrome stages 0–3 demonstrates that both the C-reactive protein-triglyceride-glucose index (CTI) and the cholesterol-high-density lipoprotein-glucose index (CHG) are independently associated with incident heart disease, with CTI exhibiting slightly superior predictive performance, particularly in the early follow-up period.

Qichao Dong, Meiling Jiang, Xinyi Zheng, Zewen Yang, XinLei Wu, Hong Yu2026-07-05

📄 medicine

Nail Biting in Children With ADHD: Exploring Its Clinical Correlates, Psychiatric Comorbidities and Association With Other Body-focused Repetitive Behaviors

This retrospective study of 250 children with ADHD reveals that those who engage in nail-biting exhibit a distinct clinical profile characterized by higher rates of co-occurring body-focused repetitive behaviors and anxiety disorders, as well as reduced verbal cognitive abilities, compared to their non-nail-biting peers.

Huriye Berna Devecioğlu, Makbule Esen Öksüzoğlu2026-07-05

📄 medicine

Maternal obesity and offspring adiposity trajectories during early childhood: a longitudinal study from the PONCH cohort

This longitudinal study of the PONCH cohort reveals that children born to mothers with obesity exhibit progressively higher adiposity throughout preschool age compared to those born to mothers with normal weight or gestational diabetes, suggesting maternal obesity is a more sustained determinant of early childhood adiposity development than gestational diabetes.

Sebastian Åberg, Ulrika Andersson-Hall, Emilia Kristiansson, Agneta Holmäng2026-07-05

📄 medicine

Budget impact analysis of Gastric Alimetry® in patients with chronic gastric symptoms in the United Kingdom National Health Service

A budget impact analysis suggests that integrating the non-invasive Gastric Alimetry® system into the UK NHS for diagnosing and managing chronic gastric symptoms could generate nearly £50 million in net cost savings over 5.4 years by significantly reducing hospital admissions, emergency visits, and other healthcare resource utilization compared to the current standard of care.

Mikaela Law, Eva Fuchs, Natalia Zarate-Lopez, Charlotte Daker, Asma Fikree, Christopher N. Andrews2026-07-05

📄 medicine

Zone 3 thoracic endovascular aortic repair for retrograde type A aortic dissection: a case series

This case series of five patients demonstrates that zone 3 thoracic endovascular aortic repair (TEVAR) is a feasible and safe endovascular treatment option for retrograde type A aortic dissection, achieving complete aortic remodeling with favorable early outcomes and no major complications in selected individuals.

Yuri Murakami, Takao Ohki, Takehiro Suzuki, Naoki Toya2026-07-05

📄 medicine

Astigmatism Shift in Low-Astigmatism Myopic Children Wearing Highly Aspherical Lenslets: A Self- Controlled Cohort Study

This self-controlled cohort study reveals that highly aspherical lenslets (HAL) accelerate astigmatism progression exclusively in myopic children with low baseline astigmatism by disrupting the compensatory balance between corneal and internal astigmatism, without compromising the treatment's core efficacy in controlling axial elongation.

Kaihuai Yu, Yuejia Peng, Jin Zhang, Haoqi Lan, Qiaolan Zheng, Jie Chen, Wuhe Chen2026-07-05

📄 medicine

Low Expression of Iron–Sulfur Cluster Binding Protein RFESD Predicts Adverse Clinic Outcomes in Acute Myeloid Leukemia

This study identifies low expression of the iron–sulfur cluster binding protein RFESD as an independent predictor of adverse clinical outcomes and immune-related dysregulation in acute myeloid leukemia (AML) patients, establishing it as a valuable prognostic biomarker.

Jiajia Yuan, Yin Zhao, Xiaodan Wang, Huan Shao2026-07-05

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