📄 medicine

Serum Ferritin and Hematological Indices in Children with Attention-Deficit/Hyperactivity Disorder: A Matched Case-Control Study

This matched case-control study demonstrates that children with ADHD have significantly lower serum ferritin and iron levels compared to healthy controls, indicating that altered iron metabolism and depleted iron stores may play a role in the disorder's pathophysiology even when routine hematological indices appear normal.

Ezatollah Abbasi, Alireza Abdi, Mostafa Farshi2026-07-06
📄 medicine

In-Hospital Cardiac Arrest in a Resource-Limited Emergency Department: Clinical Characteristics, Outcomes, and Predictors of Return of Spontaneous Circulation in Somalia

This prospective study of 240 in-hospital cardiac arrest patients in a resource-limited Somali emergency department reveals extremely poor survival rates (7.4% ROSC, 1.6% 24-hour survival) driven by a high trauma burden, frequent unwitnessed arrests, and systemic infrastructure limitations, underscoring the urgent need for improved resuscitation training and early warning systems.

Abdullahi Ahmed Ahmed, Sahra Ali Yusuf2026-07-06
📄 medicine

Motivation for Physical Activity as an Attribute of Physical Literacy in Czech Adolescents and Young Adults: A Cross-Sectional Study Research Article

This cross-sectional study of 7,466 Czech adolescents and young adults reveals that fitness/health and interest/enjoyment are the primary motives for physical activity, with notable gender differences in appearance and competence motivations, highlighting the importance of these factors for physical literacy and tailored educational interventions.

Martina Poláková¹, Jana Vašíčková², Hana Pernicová³2026-07-06
📄 medicine

Predictors of physical strain of walking in adults with spastic cerebral palsy - A cross-sectional study

This cross-sectional study of 89 ambulant adults with spastic cerebral palsy identifies older age and greater spasticity as the independent predictors of higher physical strain during walking, suggesting that clinical interventions should prioritize managing spasticity and preserving aerobic capacity to reduce physiological demands.

Sandra Linnea Klund-Hansen, Terje Gjøvaag, Arve Opheim, Eivind Lundgaard, Espen Ingvald Bengtson, Linda Rennie2026-07-06
📄 medicine

Field Trial Evaluation of the Diagnostic Accuracy of an Opisthorchis viverrini-Rapid Diagnostic Test (OV-RDT) for Opisthorchiasis in Northeast Thailand

This field trial in Northeast Thailand demonstrates that the newly developed OV-RDT offers superior diagnostic accuracy and strong agreement with antigen-based methods compared to conventional fecal examination, supporting its potential as a rapid, non-invasive point-of-care tool for large-scale opisthorchiasis screening and control.

Phattharaphon Wongphutorn, Chanika Worasith, Kanoknan Khongsukwiwat, Anchalee Techasen, Kulthida Y. Kopolrat, Watcharin (…)2026-07-06
📄 medicine

Efficacy of Nano-Formulated Nitazoxanide Compared to Bulk Powder Against Human Oral Squamous Cell Carcinoma Cell line

This study demonstrates that nano-formulated Nitazoxanide (NTZ-NS) exhibits significantly enhanced anticancer efficacy against human oral squamous cell carcinoma compared to its bulk powder form by inducing greater apoptosis, cell cycle arrest, and suppression of BCL-2 and VEGF proteins while maintaining selectivity over normal keratinocytes.

Moataz Mohamed Elkholy, Mohamed Sobhy Kishta, Beshoy Magdy M Moharib, Sara Mohamed Ali2026-07-06
📄 medicine

The Paradox of Medicalization in the Dominican Republic: High Rates of Cesarean Section, Ethnic Inequity and Maternal/Neonatal Mortality in a Context of Low Public Expenditure (2020–2024)

This study reveals that in the Dominican Republic, high cesarean section rates coexist with low public health spending and poor maternal outcomes, while Haitian women face significantly lower access to these interventions compared to Dominican women, highlighting a paradox of overmedicalization driven by ethnic inequity and structural underinvestment.

Elena Gonzalez-Rodriguez, Raul Castaneda-Vozmediano, Ruth Gil-Prieto2026-07-06
📄 medicine

Smoking status stratifies Th 1 /Th 2 phenotypes in pre-COPD high-risk individuals: quantile-specific blood biomarkers for primary care

This study demonstrates that smoking status stratifies distinct Th1/Th2 immune phenotypes in pre-COPD high-risk individuals, revealing quantile-specific blood biomarkers that detect early immune dysregulation missed by conventional methods and could serve as cost-effective screening tools in primary care.

Xiaohua Zhang, Juan Xie, Shuang Yang, Biying Wu, Jindong Shi, Xiaoying Hu2026-07-06
📄 medicine

Development and Clinical Validation of an Enhanced Deep Learning Model for Automated Segmentation and Implant Planning in Maxillary Edentulous Regions Using CBCT Images

This study developed and clinically validated a deep learning framework, specifically a Swin-UNETR model, which achieves high-accuracy automated segmentation of maxillary edentulous regions in CBCT images, significantly reducing implant planning time and improving reproducibility compared to conventional workflows.

Mehdi Abrishami, Hasan Momeni, Mehdi Rahmani, Elham Sheykhi Some2026-07-06
📄 medicine

Enrolling and retaining a representative population in the NIH Researching COVID to Enhance Recovery (RECOVER)-Adult Cohort

Although the NIH RECOVER-Adult cohort successfully enrolled a large and diverse population through targeted community outreach, the study found that retaining sociodemographically representative participants, particularly those from minoritized and vulnerable groups, proved more challenging than initial enrollment, underscoring the need for innovative retention strategies in post-pandemic research.

Jasmine Berry, Jennifer C. Gander, Jun Lu, Franchesca Amor A. Aguilar, Larissa Teunis, A. Blythe Ryerson, Sarah de Ramir (…)2026-07-06