📄 Category

medicine

5150 papers

📄 medicine

Retatrutide Treatment in Streptozotocin-Induced Diabetic Rats: Renal Inflammatory Cytokines, HIF‑1α Signalling, and Histopathological Injury Profile

This study demonstrates that while Retatrutide treatment in streptozotocin-induced diabetic rats significantly attenuates HIF-1α upregulation and shows a non-significant trend toward reducing renal inflammation and histopathological injury, it does not yet confer overt structural renoprotection, suggesting that longer durations or chronic disease models are needed to confirm its therapeutic potential.

Ulya Keskin, Eslem Altın, Fikriye Yasemin Özatik, Ayşe Koçak Sezgin, Ayşe Çakır Gündoğdu, Neziha Senem Arı, Melkan Kağan (…)2026-07-06
📄 medicine

Misconceptions, Stigma, and Mpox Prevention and Control Practices in Sierra Leone: A Cross-Sectional Study

This cross-sectional study of 6,096 participants in Sierra Leone reveals that while misconceptions about mpox (such as viewing it as a divine curse or government propaganda) significantly undermine prevention and control practices, stigma does not independently affect these behaviors, highlighting the need for targeted risk communication to address false beliefs.

Mohamed Boie Jalloh, Abdulai Alpha Jalloh, James Sylvester Squire, Ibrahim Kamara, Daam Koeloengan Clement, Mosoka Papa (…)2026-07-06
📄 medicine

Integrated Multi-Cohort Transcriptomic Meta-Analysis and Molecular Docking Identify Core Dysregulated Hub Pathways and Therapeutic Ligands in Parkinson’s Disease

This study integrates multi-cohort transcriptomic meta-analysis and molecular docking to identify DRD2 and SLC18A3 as core hub genes for a novel Parkinson's disease diagnostic model and proposes donepezil and bromocriptine as potential therapeutic ligands targeting pyroptosis and neuroinflammation pathways.

Fatima Tariq, Ezza Abbas, Zainab Ashraf, Fatima Munir, Usama Munir, Rida Amjad2026-07-06
📄 medicine

Trauma and Its Associated Factors in Patients Presenting at the Emergency Department, Intermediate Hospital, Oshakati, Namibia: Epidemiological Baseline and Implications for Contemporary Trauma Care Systems

This study establishes that trauma accounts for over 20% of emergency department visits at Oshakati Intermediate Hospital in Namibia, disproportionately affecting young unemployed males, with alcohol consumption identified as a critical modifiable risk factor driving violence and accidents, thereby highlighting the urgent need for strengthened trauma care systems and targeted prevention strategies.

Lorenta Ojo2026-07-06
📄 medicine

Perioperative Considerations and Outcomes of the Hybrid Convergent Procedure for Atrial Fibrillation: A Prospective Observational Study

This prospective observational study demonstrates that the hybrid convergent procedure for atrial fibrillation offers a favorable perioperative profile with low major complication rates and short ICU stays, despite common early postoperative pericarditis and arrhythmias, while achieving meaningful long-term rhythm control in the majority of patients.

Bradley Wibrow, Pragnesh Joshi, Rukshen Weerasooriya, Remy Spring, Patrick McCormick, Kieran Blake, Lahni Campbell, Matt (…)2026-07-06
📄 medicine

Occupational Sharps Injuries Among Healthcare Workers in Sub-Saharan Africa: Safety Practices, Risk Factors, and Professional Disparities at a Namibian Referral Hospital

A 2020 cross-sectional study at a Namibian referral hospital reveals that over half of healthcare workers experienced sharps injuries, with doctors reporting higher injury frequencies and lower safety compliance compared to nurses, highlighting the urgent need for targeted institutional interventions and improved workplace safety systems beyond mere awareness.

Lorenta Ojo, Martha Chadyiwa2026-07-06
📄 medicine

Knowledge and Attitudes Regarding Medical Sharps Handling Among Healthcare Workers in Namibia: A Contemporary Analysis

A 2020 cross-sectional study at Intermediate Hospital Oshakati in Namibia reveals that healthcare workers, particularly doctors, exhibit significant knowledge gaps and suboptimal attitudes regarding medical sharps handling and injury reporting, highlighting an urgent need for targeted educational interventions and improved post-exposure protocols.

Lorenta Ojo, Martha Chadyiwa2026-07-06
📄 medicine

Respiratory Health Consequences of Active Smoking, Second-Hand Smoke Exposure, and Electronic Cigarette Use: A Mini Literature Review

This mini literature review synthesizes evidence from 2020 to 2025 demonstrating that active smoking, second-hand smoke exposure, and electronic cigarette use all significantly contribute to respiratory morbidity through overlapping inflammatory and oxidative stress mechanisms, underscoring the urgent need for comprehensive tobacco control and regulation of emerging nicotine delivery systems.

Rasya Aprilio Rosyidi, Moses Glorino Rumambo Pandin2026-07-06
📄 medicine

Anterior to Psoas Corridor, Does It Really Exist?! An MRI Analysis

This MRI study demonstrates that the anterior-to-psoas corridor for oblique lumbar interbody fusion narrows progressively from L1 to L5 and is modestly widened by right-lateral positioning, indicating that preoperative imaging in the surgical position is essential to determine safe cage dimensions and the potential need for psoas retraction.

Thiago Coutinho, Carlos Tucci, Alexandre Cristante Fogaça, Raphael Martus Macron, Tacísio Eloy Pessoa de Barros Filho, M (…)2026-07-06