medicine papers | Gist.Science

30-Day Mortality Risk Prediction Model for Intracerebral Hemorrhage Patients Combined with Albumin Infusion Characteristics

This study developed and validated a Logistic Regression model using MIMIC-IV and MIMIC-III data to predict 30-day mortality in intracerebral hemorrhage patients with albumin infusion characteristics, achieving strong predictive performance (AUC > 0.80) and providing interpretable insights via SHAP analysis to guide clinical risk assessment and treatment optimization.

Xiangjun Chen, Zhigang Huang2026-07-06

📄 medicine

Antimicrobial Resistance Patterns in Uropathogens Isolated from Type 2 Diabetic Patients in a Tertiary Hospital, Ghana: A Cross-Sectional Approach

This cross-sectional study at Sunyani Teaching Hospital, Ghana, reveals a 27.6% prevalence of uropathogens among Type 2 diabetic patients, identifies Enterococcus species as the most common isolate, highlights specific risk factors and clinical markers for infection, and confirms that while multidrug resistance is prevalent, meropenem, amikacin, and levofloxacin remain highly effective treatment options.

George Owusu, Meshack Antwi-Adjei, Ibrahim Nana Boakye, Akosua Ankomaa Owusu Peprah, Mohammed Sherifa, Jones Ofori-Amoah2026-07-06

📄 medicine

Awake Percutaneous Nephrolithotomy Under Modified Local Anaesthesia: A Pilot Case Series

This pilot case series demonstrates that awake percutaneous nephrolithotomy under modified local anaesthesia is a safe and effective alternative to general anaesthesia for treating renal stones, offering high stone-free rates, stable haemodynamics, and short operative times in settings where general anaesthesia access is limited.

Thevarajah Aravinthan, Selvarasa Mathurahan2026-07-06

📄 medicine

EphB4 Inhibition Regulates Tumor Microenvironment by Promoting Immunogenic Cell Death Effector Mechanism in Breast Cancer

This study demonstrates that inhibiting EphB4 in breast cancer promotes immunogenic cell death and alters glucose metabolism via the Src/STAT3/MYC pathway, thereby transforming the tumor microenvironment from "cold" to "hot" and enhancing the efficacy of immunotherapy.

Yutong Wu, Jinyu Li, Man Li2026-07-06

📄 medicine

Exploring The Mechanism Of Duhuo In Treating Rheumatoid Arthritis

This study elucidates the mechanism by which *Angelicae Pubescentis Radix* (Duhuo) treats rheumatoid arthritis by integrating network pharmacology and experimental validation to demonstrate that its active constituents suppress synovial fibroblast proliferation and induce apoptosis through the inhibition of the PIK3CA/JAK2/PIK3CG signaling pathway.

Yunxiang Zhang, Zhongrui Tu, Mingke Yi, Yulan Fang, Chunlei Yu, Na Niu, Jianhua Chen2026-07-06

📄 medicine

To Put All the Pieces Together: An Exploratory Study of The Referral Process of Critically Ill Children in Indonesia from The Perspective of Pre-Referral Setting

This qualitative study involving 30 healthcare providers in the Yogyakarta region identifies substantial barriers within Indonesia's referral system for critically ill children, highlighting the urgent need to improve communication, human resources, and organizational services across pre-referral and referral facilities.

Desy Rusmawatiningtyas, Fitriana Murriya Ekawati, Umar Muhammad, Nurnaningsih -, Antonius H Pudjiadi, Hennie Knoester, J (…)2026-07-06

📄 medicine

Assessment of the Psychosocial and Economic Burden of Vitiligo Management Among Patients in a Community Based Cross Sectional Study

This community-based cross-sectional study of 100 vitiligo patients in Raichur, India, reveals that the condition imposes a severe psychosocial and economic burden, significantly impairing quality of life and daily functioning, thereby highlighting the urgent need for integrated community-level care involving dermatology, psychology, and pharmacy.

Binu K.M, Doddayya H, Sougath Reddy Veera, Krishnaprasad N.N, Kallappa Herakal2026-07-06

📄 medicine

From Digital to Physical model: testing of a workflow for case-specific 3D-printed bone simulants

This study evaluates the feasibility of creating case-specific 3D-printed bone simulants from CT scans for ballistic testing, finding that while PLA and PA6-CF materials failed to replicate biological fracture and penetration characteristics, thermoplastic polyurethane (TPU) prototypes showed the most promising results.

Manon Wartel, Daan Wintermans, Stefan Schaufelbühl, Wim Kerkhoff, Pia Genet, Fabiano Riva2026-07-06

📄 medicine

Determinants of Maternal Cervical Cancer Preventive Practices for Adolescent Daughters in Ibadan, Nigeria: The Influence of Risk Perception, Awareness, and Knowledge

This community-based study in Ibadan, Nigeria, reveals that maternal cervical cancer preventive practices for adolescent daughters are primarily driven by awareness and knowledge rather than risk perception, highlighting the critical need to strengthen health literacy to improve HPV vaccination uptake.

Magbagbeola David Dairo, Ademola Marvellous Adeyemi, Sururat Opeyemi Ashimi, Feranmi Motunrayo Akinboyo, Seun Taiwo Oluw (…)2026-07-06

📄 medicine

Prevalence and factors associated with illicit non-injecting drug use among individuals at high risk of HIV infection in rural southwestern Uganda

In a study of 940 adults at high risk of HIV in rural southwestern Uganda, 18.3% reported illicit non-injecting drug use, with significantly higher odds observed among sex workers, those with older sexual partners, individuals engaging with long-distance truck drivers or miners, and those having condomless sex with partners of unknown HIV status, highlighting the need for integrated substance abuse and HIV prevention strategies.

Bernadette Kalanzi Nayiga, Paul Okimat, Sylvia Kusemererwa, Ubaldo Bahemuka, Ayoub Kakande, Gertrude Mutonyi, Andrew Aba (…)2026-07-06

← Previous Next →