📄 medicine

SY-CNN+: Synthetic-Data-Enhanced Hybrid Learning for Clinical Photograph-Based Eyelid Tumor Classification

This study introduces SY-CNN+, a hybrid learning framework that leverages GAN-based synthetic data augmentation to achieve high accuracy in classifying malignant versus benign eyelid tumors from clinical photographs, outperforming human clinicians in an exploratory comparison while demonstrating robustness across retrospective and prospective cohorts.

Guanchao Tong, Yan Yan, Jiashu Li, Yixuan Sun, Jia Rong, Zixuan Chen, Jiamin Wang, Gaurav Gupta, Jiayou Chao, Kuan Huang (…)2026-07-07
📄 medicine

Facilitators and barriers in adolescents accessing public mental healthcare services in Nairobi, Kenya

This qualitative study conducted in Nairobi, Kenya, identifies key facilitators and barriers affecting adolescents' access to public mental healthcare services, highlighting the urgent need for collaborative, community-anchored strategies to strengthen the region's underdeveloped mental health system.

Elizabeth Wambui, Simeon Kintu Paul, Joan Watiri, Marcia Nderi, Stella Waruingi, Frederick Murunga Wekesah, Daniel Mwang (…)2026-07-07
📄 medicine

Do preceptorship Program support the clinical competency of Critical care nurses? A triangulation measurement

This quasi-experimental study demonstrates that a six-week designed preceptorship program significantly enhances the clinical competency of novice intensive care unit nurses, as evidenced by statistically significant improvements in evaluations from head nurses and peers, though not from the nurses' self-assessments.

Sajede Esmaeili Sorboni, Zohre Pouresmail, Maryam Bagheri, Fatemeh Heshmati Nabavi2026-07-07
📄 medicine

Anxio-depressive disorders among survivors of the April 2020 floods in Uvira, South Kivu, Democratic Republic of Congo: prevalence, determinants, and psychosocial experience in a context of systemic fragility

This mixed-methods study reveals that survivors of the April 2020 floods in Uvira, DRC, experienced exceptionally high rates of co-occurring anxiety and depression (over 70%), driven by a unique "compound vulnerability" of armed conflict, displacement, and bereavement that standard humanitarian frameworks fail to address.

Julien KASAMBI BAYANDA, Gaston KASAMBI BITAMBWE, LILIANE SENGIMA, Alain SIKOSIKO2026-07-07
📄 medicine

Construction of a Recertification Evaluation Index System for Advanced Practice Nurses in China Based on the Magnet Framework: A Mixed-Methods Study

This mixed-methods study constructs a scientifically valid and clinically practical recertification evaluation index system for Advanced Practice Nurses in China, comprising 5 primary, 11 secondary, and 45 tertiary indicators based on the Magnet framework to address the current lack of a unified national standard.

Tingting Dong¹, Fengxia Xu, Xiao Zhou, Zijuan Yu¹2026-07-07
📄 medicine

Medulloblastoma Management Outcomes: A Multicenter Retrospective Cohort Study from Ethiopia (2018–2025) showing improved early survival despite persistent late decline

This multicenter retrospective study from Ethiopia (2018–2025) demonstrates that while medulloblastoma patients show improved early survival compared to historical data, long-term outcomes remain poor, with gross total resection and older age predicting better survival, whereas brainstem compression, postoperative complications, and delayed radiotherapy significantly increase mortality risk.

Alemu Gemeda Bedaso, Sebboona B. Abelti, Yemisirach B. Akililu, Samuel M Fetene, Kedir D. Guduru, Pineal Z. Abera2026-07-07
📄 medicine

A multicenter randomized placebo-controlled trial evaluating daidzein-rich isoflavone aglycones in endometriosis-associated dysmenorrhea

This multicenter randomized placebo-controlled trial suggests that daidzein-rich isoflavone aglycones (DRIAs) offer a safe, non-hormonal therapeutic option for endometriosis-associated dysmenorrhea, demonstrating a statistically significant pain reduction at Month 3 and a consistent trend toward efficacy without suppressing ovarian function.

Osamu Takaoka, Hiroyuki Okimura, Yosuke Tarumi, Mari Kawamata, Fumitake Ito, Akemi Koshiba, Izumi Kusuki, Jo Kitawaki, T (…)2026-07-07
📄 medicine

Population Attributable Fraction and Potential Impact Fraction of Selected Risk Factors for Childhood Acute Lymphoblastic Leukemia: A Case-Control Study in Alborz Province, Iran

This case-control study in Alborz Province, Iran, identifies several significant modifiable risk factors for childhood acute lymphoblastic leukemia, including maternal imaging during pregnancy and exposure to high-voltage power lines, and quantifies their substantial population-level impact to inform targeted preventive strategies.

Omid Safari, Parnian Ahmadvand, Homa Sadri, Mahmood Bakhtiari, Sabahat Haghi, Mohammad Reza Mohammadi Sardo, Amirhossein (…)2026-07-07
📄 medicine

Appendicular skeletal muscle index and bone mineral density in postmenopausal women: The moderating role of BMI and site-specific differences between lumbar spine and femoral neck

This study demonstrates that in postmenopausal women, the protective effect of appendicular skeletal muscle index on bone mineral density is significant only in non-overweight/obese individuals and is attenuated by high BMI, while the influence of body composition on bone density exhibits distinct site-specific differences between the lumbar spine and femoral neck.

Qingqiang Huang, Xiaohong Chen2026-07-07