5451 papers
This study identifies a distinct serum metabolomic signature in autoimmune gastritis characterized by acylcarnitine and amino acid alterations linked to mitochondrial dysfunction, establishing the C2/C0 ratio as a promising non-invasive diagnostic biomarker.
This multicenter cross-sectional study of 634 neonates in China found that feeding patterns are significantly associated with sleep duration and nighttime awakenings, with formula-fed infants exhibiting longer daytime sleep but shorter nighttime sleep and more frequent awakenings compared to exclusively breastfed infants.
This study validates the ORPI-26 survey as a reliable tool for assessing residency graduates' self-perceived preparedness in Oman, revealing high overall readiness but identifying specific deficits in systems-based practice, legal/risk management, and research planning that warrant targeted curricular improvements.
This prospective comparative study of 74 patients found that while closed endonasal septoplasty offers shorter operative times and less early postoperative pain, open approach septoplasty yields superior quality of life outcomes and fewer complications at one month, particularly for complex septal deviations.
This 2024 mixed-methods study in Mattu Town, Ethiopia, reveals that despite high latrine coverage and disease knowledge, critical deficiencies in water quality, handwashing facilities, and waste management persist, necessitating a shift from general awareness campaigns to targeted infrastructure improvements and specific behavioral interventions.
This study synthesizes 25 best pieces of evidence from 15 high-quality sources to provide a comprehensive, evidence-based framework for postoperative pain management in elderly patients with hip fragility fractures, covering assessment, pharmacological and non-pharmacological interventions, and health education.
This cross-sectional study of 385 Brazilian medical students reveals that while self-assessed palliative care competencies generally improve throughout medical training, significant gaps remain in care coordination, teamwork, and self-awareness, highlighting the urgent need to strengthen palliative care education in Brazil.
This retrospective cohort study of 395 hospitalized COVID-19 patients reveals that elderly males face the highest risk of severe disease and multi-organ complications due to a synergistic effect of age- and sex-related immune dysregulation, underscoring the critical need for tailored therapeutic strategies rather than a one-size-fits-all approach.
This mixed-methods study of general practitioners in private clinics in Eastern Indonesia reveals that perceived medication error prevention is primarily driven by effective digital workflow alignment, which is significantly influenced by AI readiness, digital competency, EMR system quality, and peer influence, while remaining unaffected by capitation-based financing regulations.
This case report describes a rare instance of a pediatric cerebellar pilocytic astrocytoma with a high Ki-67 index and KIAA1549-BRAF fusion that exhibited exceptionally rapid recurrence despite surgical resection, but achieved durable disease control following the initiation of targeted trametinib and dabrafenib therapy.