📄 Category

medicine

5451 papers

📄 medicine

Bentall procedure for pseudoaneurysm of mitral-aortic intervalvular fibrosa in a patient with Y- incision root enlargement: a case report

This case report describes the successful treatment of a rare pseudoaneurysm of the mitral-aortic intervalvular fibrosa in a 42-year-old woman, which developed two years after aortic valve replacement with Y-incision root enlargement, through a Bentall procedure following a diagnosis complicated by mechanical valve artifacts and ineffective antibiotic therapy for Staphylococcus capitis bacteremia.

Shibo Song, Feimin Shen, Shaoling Chen, Mingcheng Huang, Bin You, Yuxin Kang, Wencong Yang, Jinping Liu2026-07-07
📄 medicine

Capillary associated macrophages regulate vascular permeability through VEGF / PI3K / Akt pathway to affect the effect of lung cancer chemotherapy

This study reveals that capillary-associated macrophages (CAMs) promote lung cancer chemotherapy resistance by increasing vascular permeability via the VEGF/PI3K/Akt pathway, and demonstrates that depleting CAMs or blocking this signaling axis significantly enhances drug delivery and therapeutic efficacy.

Yafeng Zhang, Benting Ma, Wentian Zhang, Lei Jiang2026-07-07
📄 medicine

Evaluation of risk prediction models for coronary artery disease: a systematic review, meta- analysis, and machine learning validation

This systematic review and meta-analysis of 68 studies reveals that while existing coronary artery disease risk prediction models show moderate discriminative ability, their high risk of bias and heterogeneity limit clinical applicability, suggesting a need for future research focused on specific subgroups and machine learning-based models.

Tanglin Ouyang, Daoxi Qi, Xinxin Miao, Xinai Xie, Xinyu Deng, Fan Wang, Liang Cao, Chang Zhao, Ruiyang Zhu, Shuyang Shen (…)2026-07-07
📄 medicine

Low agreement between self- and informant-reports in ADHD symptoms and executive functioning in parents of children with ADHD

This study reveals that parents of children with ADHD show low to moderate agreement between their self-reports and informant reports regarding ADHD symptoms and executive functioning, suggesting that such discrepancies likely stem from genuine differences in perspective rather than simple self-report bias.

Cristina Corredera Pardo, Adriana Junquera Blanco, Sonia Perez Aranda, Pablo Albarracin Marcos, Alicia Lopez Toledo, Pat (…)2026-07-07
📄 medicine

Grip strength, walking pace, and hospital-record-defined incident degenerative cervical myelopathy: a UK Biobank cohort study

This UK Biobank cohort study of over 500,000 participants demonstrates that lower grip strength and slower walking pace are independently associated with an increased risk of incident degenerative cervical myelopathy, offering modest risk enrichment for early clinical suspicion but insufficient standalone value for screening or replacing standard neurological evaluation.

Simin Yang, Le Kang, Yuqian Yang, Jiahao Du, Zhenhui Wang, Shengxuan Ding, Xiangwei He, Shuizhong Cen2026-07-07
📄 medicine

Heparin-Associated, Sustained Hospital-Acquired Hyperkalemia: The Forgotten Culprit in the Inpatient Setting? A Case Report with Review of the Literature

This case report describes a patient with Crohn's disease who developed refractory hospital-acquired hyperkalemia due to heparin-induced aldosterone suppression, highlighting the need for clinicians to consider this reversible and underdiagnosed adverse effect when managing unexplained hyperkalemia in inpatients.

Marios Prikis, Kanza Haq2026-07-07
📄 medicine

Implementation of a novel musculoskeletal physical exam curriculum in an internal medicine residency

A novel musculoskeletal physical exam curriculum implemented during the 2023-2024 academic year significantly improved internal medicine residents' confidence and, for shoulder and lumbar spine workshops, their objective physical exam competence, though the knee workshop did not yield a statistically significant improvement in observed skills.

Marc Gutierrez, Elizabeth Willis, Akruti Prabhakar, Timothy Lo, Amie Kim, Nicholas Zingas, Kelsey R Wilson, Kathryn M Bu (…)2026-07-07
📄 medicine

Left Atrial Strain as a Predictor of Composite Ischemic Events in Patients With Atrial Fibrillation

This retrospective study of 72 patients with atrial fibrillation demonstrates that reduced left atrial reservoir and conduit strain, measured via echocardiography, are significant independent predictors of a 2-year composite endpoint of ischemic stroke, acute coronary syndrome, and acute heart failure, suggesting their utility as adjunctive markers for cardiovascular risk stratification.

Pannathorn Tangkongpanich2026-07-07