📄 medicine

Epidemiological Criminological and Medico Legal Characteristics of Assaults and Bodily Injuries in Guinea Over a Twelve Year Period

This retrospective study of 19,050 medico-legal cases in Guinea from 2012 to 2024 reveals that assaults predominantly affect young adult males through intentional acts in public or domestic settings, underscoring the critical role of forensic medicine in judicial processes while highlighting the need for standardized prevention strategies.

Namandian TRAORÉ, Thierno Mamadou Cherif DIALLO, Ousmane CAMARA, Ousmane SOUMAH, Sia Marie OUENDENO, Djenabou BAH, Sambo (…)2026-07-07
📄 medicine

Interpretable Machine Learning for Preoperative Survival Prediction in Resected Brain Metastases: A Real-World Cohort Study with SHAP-Based Feature Attribution

This study demonstrates that interpretable machine learning models, particularly Random Forest and Logistic Regression, can effectively predict 6- and 12-month survival in patients with resected brain metastases by integrating diverse preoperative variables, with neutrophil-to-lymphocyte ratio, age, and tumor volume identified as the most consistent prognostic factors.

David Wasilewski, Martin Misch, Julia Onken, Peter Vajkoczy, Anton Früh2026-07-07
📄 medicine

A Non-invasive Nomogram for High-Risk Esophageal Varices in Cirrhosis without Transient Elastography: Development and Internal Validation

This study developed and internally validated a simple, non-invasive nomogram using routine clinical and ultrasonographic parameters (gender, hemoglobin, platelet count, right liver thickness, portal vein diameter, and spleen diameter) to effectively stratify the risk of high-risk esophageal varices in cirrhotic patients, offering a cost-effective alternative to transient elastography and endoscopy.

Yi Wu, Junyang Luo, Shuixian Yang, Shuaishuai Kong, Dan Dan Chen, Wenhui Guo, Nianfeng Fan, Zebin Wu, Yurong Gu, Zhaoxia (…)2026-07-07
📄 medicine

Tailored Personas for Self-Management in Young and Middle-Aged Patients with Systemic Lupus Erythematosus: A Qualitative Study

This qualitative study identifies five distinct patient personas among young and middle-aged systemic lupus erythematosus (SLE) patients based on their unique self-management characteristics, barriers, and needs, providing a theoretical foundation for developing tailored intervention strategies to improve disease control and quality of life.

Jiaying Chen, Long Zhang, Zhaorong Huang, Liuyuan Zhang, Yi He, Erwei Sun, Jiali Chen2026-07-07
📄 medicine

Online risk calculator and nomogram prediction model for lymphocele after radical prostatectomy combined with pelvic lymph node dissection

This study developed and validated a nomogram-based online risk calculator that effectively predicts the likelihood of lymphocele formation following radical prostatectomy with pelvic lymph node dissection by identifying key independent risk factors such as the extent of lymph node dissection, drainage duration, and dynamic skin assessment scores.

Hanjing Zhu, Juan Xie, Chenfei Chi, Sijie You, Yinjie Zhu2026-07-07
📄 medicine

Light Chain Neurofilament to HDGFL2 cryptic peptide ratio as a fluid biomarker to monitor TDP-43 dysfunction in ALS and FTD

This study demonstrates that the ratio of light chain neurofilament (NfL) to HDGFL2 cryptic peptide in cerebrospinal fluid serves as a highly specific biomarker for monitoring TDP-43 dysfunction and improving diagnostic accuracy in ALS and FTD patients.

Irene Santos-García, Katherine Irwin, Patricia Garay-Albizuri, Juan Pablo Garcés, Fermin Moreno-Izco, Javier Ruiz-Martin (…)2026-07-07
📄 medicine

Shifting care-seeking pathways for childhood illness: differential evidence from five years of integrated community case management in Busia County, Kenya

This study demonstrates that while Integrated Community Case Management in Busia County, Kenya, successfully shifted care-seeking pathways for childhood malaria to community health volunteers between 2017 and 2022, its impact on acute respiratory infections and diarrhoea remained limited due to persistent commodity stockouts and uneven coverage.

Elizabeth Echoka, Anthony Macharia, Moses Mwangi, David Mathu, Richard Mutisya, Rodgers Ochieng, Virginia Namikoye, Emma (…)2026-07-07
📄 medicine

Comparative Outcomes of Direct Impella Use vs. Intra-Aortic Balloon Pump (IABP)-to- Impella Escalation Strategy in Cardiogenic Shock: Insights from the National Inpatient Sample

In patients with cardiogenic shock, initiating Impella support directly rather than escalating from an IABP is associated with similar in-hospital mortality but significantly shorter hospital stays, lower costs, fewer transfusions, and lower rates of subsequent durable LVAD implantation or heart transplantation.

Xiaojia Lu, Aditi Patel, Romani Wahba, Peng Cai, Omar Khalil, Racha Ghousaini, Kirollos Gabrah, Inna Tchoukina, Melissa (…)2026-07-07