5451 papers
This study demonstrates that intradermal injection of botulinum toxin type A in a porcine skin model is safe and induces increased fibroblast proliferation and collagen type I expression without causing significant changes in collagen density or arrangement.
This matched case-control study demonstrates that children with ADHD have significantly lower serum ferritin and iron levels compared to healthy controls, indicating that altered iron metabolism and depleted iron stores may play a role in the disorder's pathophysiology even when routine hematological indices appear normal.
This prospective study of 240 in-hospital cardiac arrest patients in a resource-limited Somali emergency department reveals extremely poor survival rates (7.4% ROSC, 1.6% 24-hour survival) driven by a high trauma burden, frequent unwitnessed arrests, and systemic infrastructure limitations, underscoring the urgent need for improved resuscitation training and early warning systems.
This cross-sectional study of 7,466 Czech adolescents and young adults reveals that fitness/health and interest/enjoyment are the primary motives for physical activity, with notable gender differences in appearance and competence motivations, highlighting the importance of these factors for physical literacy and tailored educational interventions.
This cross-sectional study of 89 ambulant adults with spastic cerebral palsy identifies older age and greater spasticity as the independent predictors of higher physical strain during walking, suggesting that clinical interventions should prioritize managing spasticity and preserving aerobic capacity to reduce physiological demands.
This field trial in Northeast Thailand demonstrates that the newly developed OV-RDT offers superior diagnostic accuracy and strong agreement with antigen-based methods compared to conventional fecal examination, supporting its potential as a rapid, non-invasive point-of-care tool for large-scale opisthorchiasis screening and control.
This study demonstrates that nano-formulated Nitazoxanide (NTZ-NS) exhibits significantly enhanced anticancer efficacy against human oral squamous cell carcinoma compared to its bulk powder form by inducing greater apoptosis, cell cycle arrest, and suppression of BCL-2 and VEGF proteins while maintaining selectivity over normal keratinocytes.
This study reveals that in the Dominican Republic, high cesarean section rates coexist with low public health spending and poor maternal outcomes, while Haitian women face significantly lower access to these interventions compared to Dominican women, highlighting a paradox of overmedicalization driven by ethnic inequity and structural underinvestment.
This study demonstrates that smoking status stratifies distinct Th1/Th2 immune phenotypes in pre-COPD high-risk individuals, revealing quantile-specific blood biomarkers that detect early immune dysregulation missed by conventional methods and could serve as cost-effective screening tools in primary care.
This study developed and clinically validated a deep learning framework, specifically a Swin-UNETR model, which achieves high-accuracy automated segmentation of maxillary edentulous regions in CBCT images, significantly reducing implant planning time and improving reproducibility compared to conventional workflows.