📄 medicine

Ketamine harm reduction: Collaborative development of a prevention ecosystem using data from the northwest of England

This study employs a participatory action research approach in northwest England to map the social determinants and service gaps driving ketamine misuse among young people, ultimately proposing a collaborative prevention ecosystem that integrates community co-production with systemic responses to mitigate irreversible harms.

Rabya Mughal, Elaine Ryan-McNeill, Barbara Mezes, Pauline Wigglesworth, Laura Braithwaite, Helen Chatterjee2026-07-07
📄 medicine

Morphological Features of Deep Cervical Lymph Nodes: Potential Novel Markers for Assessing Parkinson’s Disease Severity

This study demonstrates that reduced size and altered morphology of deep cervical lymph nodes in Parkinson's disease patients correlate with impaired glymphatic function and disease severity, suggesting these lymph nodes serve as promising non-invasive biomarkers for assessing the condition.

Zhaoying Dong, Xinyi Du, Zhife Zhang, Xiaohan Li, Yu Ai, Chenyu Zhang, Oumei Cheng, Yongan Sun2026-07-07
📄 medicine

3D Multiscan Stitching enables Large-Volume-Recording of Abdominal Ultrasound Imaging in Phantoms and Patients

This pilot study demonstrates that 3D multiscan stitching is technically feasible for generating standardized large-volume abdominal ultrasound datasets in phantoms, healthy volunteers, and patients with liver disease, enabling retrospective review and structured documentation while highlighting the need for further validation of geometric accuracy and diagnostic performance before broader clinical implementation.

Valentin Blank, Paula Schwabe, Johannes Wiegand, Thomas Karlas2026-07-07
📄 medicine

Within-person increases in crisis-related distress track worsening adolescent depression, anxiety, and health-related quality of life – A post-COVID-19 longitudinal multilevel change analysis

This longitudinal study of German adolescents demonstrates that within-person increases in pandemic-related distress are significantly associated with concurrent worsening of depression, anxiety, and health-related quality of life, even after controlling for individual stressors and protective resources, highlighting the continued relevance of crisis-related distress for mental health in the post-pandemic era.

Norma Ruf, Eric Rost, Tobias Issler, Johanna Lass-Hennemann, Marie Roxanne Sopp, Monika Equit, Tanja Michael2026-07-07
📄 medicine

Effect of 1% Nanocurcumin Incorporation on the Flexural Strength, Solubility, and Water Sorption of Calcimol LC and TheraCal PT Pulp Capping Materials: An In Vitro Study

This in vitro study found that while incorporating 1% nanocurcumin into Calcimol LC and TheraCal PT pulp capping materials significantly reduced their flexural strength, it did not significantly alter their water sorption or solubility, with all tested materials still meeting acceptable criteria for clinical use.

Nastaran Dabiri, Ladan Ranjbar Omrani, Mohammad javad Kharazifard, Fatemesadat Ahmadi2026-07-07
📄 medicine

The effect of undergraduate clinical training on dental students' perceptions of paediatric behaviour management techniques: a longitudinal cohort study

This longitudinal cohort study demonstrates that undergraduate clinical training significantly influences dental students' evolving perceptions of paediatric behaviour management, revealing a strong preference for communicative and reinforcement-based techniques over restrictive approaches while highlighting the need for curricula that explicitly integrate communication and ethical reflection.

Nerea Sanz Pablos, Natalia del Río Cantero, Joany Gouveia Venezel, Alberto Adanero Velasco, Laura Velayos Galán, Marta P (…)2026-07-07
📄 medicine

Tuberculosis-related stigma among Chinese adolescents: A scoping review of prevalence, influencing factors, assessment tools, and nursing interventions

This scoping review synthesizes evidence from 30 studies to characterize the moderate-to-severe prevalence and multifaceted drivers of tuberculosis stigma among Chinese adolescents, highlighting the limitations of current interventions and proposing a comprehensive, adolescent-centered multi-dimensional nursing framework to guide future practice and research.

Yaru Wang¹, Dongmei Zheng, Kunfei Yuan, Yalan Su2026-07-07
📄 medicine

Effects of animal-assisted therapy on anxiety in children undergoing pediatric dental care: a randomized crossover clinical trial

This randomized crossover clinical trial found that while animal-assisted therapy significantly improved child behavior during pediatric dental procedures, it did not produce statistically significant reductions in fear or pain compared to the control group.

Juliane Carla Taufer, Bernardo Antonio Agostini, Juliana Gottlieb Sebem, Bárbara Raíssa Budke, Fernanda Ruffo Ortiz2026-07-07
📄 medicine

The Good, the Bad and the Ugly - Novel Synoptic Variables in the Personalisation of Colon Cancer Treatment

This review demonstrates that incorporating novel histopathological variables—specifically tumour-infiltrating lymphocytes, tumour budding, and poorly differentiated clusters—into standard reporting offers superior, cost-effective insights for refining risk stratification and personalizing adjuvant treatment strategies in stage I-III colon cancer.

Sean Davis, Matthew Watson, Zachary Bunjo, Andrew Ruszkiewicz, Tharani Krishnan, Tarik Sammour, Ryash Vather2026-07-07