5681 papers
This case report details two Asian Indian men with markedly divergent outcomes following honeybee sting–induced ischemic stroke, illustrating the condition's complex pathophysiology and variable prognosis while emphasizing the critical need for early neurological assessment and comprehensive management in mass envenomation cases.
This study developed and validated a Logistic Regression model using MIMIC-IV and MIMIC-III data to predict 30-day mortality in intracerebral hemorrhage patients with albumin infusion characteristics, achieving strong predictive performance (AUC > 0.80) and providing interpretable insights via SHAP analysis to guide clinical risk assessment and treatment optimization.
This cross-sectional study at Sunyani Teaching Hospital, Ghana, reveals a 27.6% prevalence of uropathogens among Type 2 diabetic patients, identifies Enterococcus species as the most common isolate, highlights specific risk factors and clinical markers for infection, and confirms that while multidrug resistance is prevalent, meropenem, amikacin, and levofloxacin remain highly effective treatment options.
This pilot case series demonstrates that awake percutaneous nephrolithotomy under modified local anaesthesia is a safe and effective alternative to general anaesthesia for treating renal stones, offering high stone-free rates, stable haemodynamics, and short operative times in settings where general anaesthesia access is limited.
This study demonstrates that inhibiting EphB4 in breast cancer promotes immunogenic cell death and alters glucose metabolism via the Src/STAT3/MYC pathway, thereby transforming the tumor microenvironment from "cold" to "hot" and enhancing the efficacy of immunotherapy.
This study elucidates the mechanism by which *Angelicae Pubescentis Radix* (Duhuo) treats rheumatoid arthritis by integrating network pharmacology and experimental validation to demonstrate that its active constituents suppress synovial fibroblast proliferation and induce apoptosis through the inhibition of the PIK3CA/JAK2/PIK3CG signaling pathway.
This qualitative study involving 30 healthcare providers in the Yogyakarta region identifies substantial barriers within Indonesia's referral system for critically ill children, highlighting the urgent need to improve communication, human resources, and organizational services across pre-referral and referral facilities.
This community-based cross-sectional study of 100 vitiligo patients in Raichur, India, reveals that the condition imposes a severe psychosocial and economic burden, significantly impairing quality of life and daily functioning, thereby highlighting the urgent need for integrated community-level care involving dermatology, psychology, and pharmacy.
This study evaluates the feasibility of creating case-specific 3D-printed bone simulants from CT scans for ballistic testing, finding that while PLA and PA6-CF materials failed to replicate biological fracture and penetration characteristics, thermoplastic polyurethane (TPU) prototypes showed the most promising results.
This community-based study in Ibadan, Nigeria, reveals that maternal cervical cancer preventive practices for adolescent daughters are primarily driven by awareness and knowledge rather than risk perception, highlighting the critical need to strengthen health literacy to improve HPV vaccination uptake.