📄 medicine

Associations of C-reactive protein-triglyceride-glucose index and Cholesterol- high-density lipoprotein-glucose index with heart disease risk in individuals with cardiovascular-kidney-metabolic syndrome stages 0-3: a cohort study from CHARLS

This cohort study of 6,740 individuals with cardiovascular-kidney-metabolic syndrome stages 0–3 demonstrates that both the C-reactive protein-triglyceride-glucose index (CTI) and the cholesterol-high-density lipoprotein-glucose index (CHG) are independently associated with incident heart disease, with CTI exhibiting slightly superior predictive performance, particularly in the early follow-up period.

Qichao Dong, Meiling Jiang, Xinyi Zheng, Zewen Yang, XinLei Wu, Hong Yu2026-07-05
📄 medicine

Nail Biting in Children With ADHD: Exploring Its Clinical Correlates, Psychiatric Comorbidities and Association With Other Body-focused Repetitive Behaviors

This retrospective study of 250 children with ADHD reveals that those who engage in nail-biting exhibit a distinct clinical profile characterized by higher rates of co-occurring body-focused repetitive behaviors and anxiety disorders, as well as reduced verbal cognitive abilities, compared to their non-nail-biting peers.

Huriye Berna Devecioğlu, Makbule Esen Öksüzoğlu2026-07-05
📄 medicine

Maternal obesity and offspring adiposity trajectories during early childhood: a longitudinal study from the PONCH cohort

This longitudinal study of the PONCH cohort reveals that children born to mothers with obesity exhibit progressively higher adiposity throughout preschool age compared to those born to mothers with normal weight or gestational diabetes, suggesting maternal obesity is a more sustained determinant of early childhood adiposity development than gestational diabetes.

Sebastian Åberg, Ulrika Andersson-Hall, Emilia Kristiansson, Agneta Holmäng2026-07-05
📄 medicine

Budget impact analysis of Gastric Alimetry® in patients with chronic gastric symptoms in the United Kingdom National Health Service

A budget impact analysis suggests that integrating the non-invasive Gastric Alimetry® system into the UK NHS for diagnosing and managing chronic gastric symptoms could generate nearly £50 million in net cost savings over 5.4 years by significantly reducing hospital admissions, emergency visits, and other healthcare resource utilization compared to the current standard of care.

Mikaela Law, Eva Fuchs, Natalia Zarate-Lopez, Charlotte Daker, Asma Fikree, Christopher N. Andrews2026-07-05
📄 medicine

Astigmatism Shift in Low-Astigmatism Myopic Children Wearing Highly Aspherical Lenslets: A Self- Controlled Cohort Study

This self-controlled cohort study reveals that highly aspherical lenslets (HAL) accelerate astigmatism progression exclusively in myopic children with low baseline astigmatism by disrupting the compensatory balance between corneal and internal astigmatism, without compromising the treatment's core efficacy in controlling axial elongation.

Kaihuai Yu, Yuejia Peng, Jin Zhang, Haoqi Lan, Qiaolan Zheng, Jie Chen, Wuhe Chen2026-07-05
📄 medicine

Investigation of Plasmodium Species in Donated Stored Blood Units at Ndola Teaching Hospital, Ndola, Copperbelt Province, Zambia

This study reveals that 8% of ready-to-transfuse blood units at Ndola Teaching Hospital in Zambia contain *Plasmodium* parasites, predominantly *P. falciparum*, highlighting a critical, unmonitored risk of transfusion-transmitted malaria that necessitates the inclusion of malaria screening in national blood safety protocols.

Patrick Loti, Frank Chisulo K., Agness Chama, Alick Mwambungu, Karen Chanda, Mazuba Banda2026-07-05
📄 medicine

Clinical Validation of Orthodontic Oral Health Literacy and Behavior Tools (OHL-Ortho & OHB): A Cross-Sectional Assessment Using CPITN, OHI-S and Objective Knowledge Measures

This study provides the first clinical validation of the newly developed OHL-Ortho and OHB instruments, demonstrating their strong reliability and significant ability to predict factual knowledge, oral hygiene behaviors, and clinical periodontal outcomes in adult patients undergoing fixed orthodontic treatment.

Muhammad Raif Ilyas, Syed Muhammad Ali Gilani, Muhammad Mughni, Mubassar Fida, Rashna Hoshang Sukhia2026-07-05
📄 medicine

Reliability and Clinical Accuracy of ChatGPT in Post-FESS Counselling: A Multi-Reviewer Evaluation.

This study evaluates ChatGPT's performance in generating postoperative FESS counseling, finding that while it offers acceptable reliability for standardized guidance with high inter-rater agreement on appropriateness, it exhibits limitations in contextual accuracy and readability that necessitate clinician oversight.

PARAMITA DEBNATH, MISBAHUL HAQUE, PRAKRITI SAMADDAR, NEHA YADAV2026-07-05