5681 papers
This pilot study demonstrates that while biofeedback-guided inhalation using electrical impedance tomography did not improve obstructive lung parameters (FEV1) in COPD patients, it significantly reduced hyperinflation (FRC) compared to standard inhalation, suggesting potential benefits for inhalation technique and lung volume management.
This large population-based study utilizing MIMIC-IV and EICU-CRD databases reveals that a higher atherogenic index of plasma (AIP) is independently and non-linearly associated with increased 168-hour mortality in sepsis patients, with lactate metabolism and organ dysfunction serving as key mediating mechanisms.
This retrospective study of 30 patients with fibrillary glomerulonephritis highlights the disease's heterogeneous clinical presentation and generally poor kidney outcomes, with over half progressing to end-stage kidney disease and higher serum creatinine at biopsy identified as the sole predictor of progression.
This case report describes a rare instance of a patient experiencing two separate, life-threatening episodes of dialysis-dependent acute kidney injury caused by distinct mechanisms (gentamicin-induced toxic tubular necrosis and hantavirus-induced immune-mediated interstitial nephritis) over a 12-year period, both of which resulted in complete renal recovery without progression to chronic kidney disease.
This pre-post study demonstrates that instructor-led Basic Life Support training significantly improves CPR knowledge across healthcare professionals, medical students, and laypeople, effectively equalizing theoretical scores regardless of prior background while revealing distinct learning patterns such as cognitive interference for experts and a theoretical-practical gap for laypeople.
This finite element analysis demonstrates that a novel Micro-Adjustable External Fixation (MAEF) device provides superior biomechanical stability and stress distribution compared to traditional percutaneous short-segment intermediate screw fixation (PSISF), potentially reducing postoperative complications and accelerating fracture healing in thoracolumbar fractures.
This study identifies the dysregulation of the TCR-mediated inside-out signaling pathway, particularly involving the adaptor protein SKAP1, as a key mechanism driving central nervous system infiltration and relapse in pediatric T-cell acute lymphoblastic leukemia.
This prospective study of older male dental patients demonstrates that diagonal earlobe creases are significantly associated with calcified cervical carotid artery atheromas detected on cone beam CT, suggesting that the presence of these creases may serve as a clinical risk indicator for future myocardial infarction.
This paper investigates the multifactorial link between breast and subsequent thyroid cancer, concluding that while increased medical surveillance likely explains most cases, shared genetic susceptibility (such as *CHEK2* mutations) and treatment effects also contribute to the association.
This cross-sectional study of 358 clinical nurse preceptors in China utilized latent profile analysis to identify three distinct subgroups based on teaching self-efficacy and clinical teaching behaviors, revealing that older age, established employment, higher professional titles, and more extensive experience and training are significantly associated with membership in higher-performing profiles.