📄 Category

medicine

5683 papers

📄 medicine

The Severity Paradox of Metropolitan Traffic Trauma: Geographic Administrative Boundaries as an Independent Predictor of Anatomical Injury Severity

This retrospective cohort study of over 5,000 traffic crash patients in Taiwan reveals that geographic administrative boundaries (specifically New Taipei City versus Taipei City) serve as a potent independent predictor of major trauma severity, even after controlling for physiological status, thereby highlighting the need for region-specific triage protocols that prioritize location and age over traditional physiological triggers.

Mon-Chun Chen, Chun-Man Kuo, Ching-Lin Chen2026-07-03
📄 medicine

Polygenic Risk Scores in the Early Detection of Cancer and Autoimmune Disease in Patients with Non-Specific Symptoms: Insights from the SCAN Cohort

This study of the SCAN cohort demonstrates that while polygenic risk scores offer modest incremental value for stratifying cancer risk in patients with non-specific symptoms, they show strong, consistent associations with various autoimmune diseases, suggesting a more immediate role for PRS integration in autoimmune diagnostics compared to cancer screening.

Dimitrios V. Vavoulis, Anthony Cutts, Carla Giner-Delgado, Stephen Ash, Georgetta Ciuban, Helene Dreau, Francoise Howe (…)2026-07-03
📄 medicine

Concurrent validity of fixed-frame vs handheld dynamometer assessment of isometric neck strength

This study found that fixed-frame and handheld dynamometers show only moderate to weak correlations in assessing isometric neck strength among female rugby players, indicating that these testing protocols should not be used interchangeably and that a single system should be consistently applied for longitudinal monitoring.

Bradley James Hornsey, Nicola Sewry, Martin Jordaan, Candice MacMillan2026-07-03
📄 medicine

The relationship between sexual function and body mass index in menopause: a systematic review and meta-analysis

This systematic review and meta-analysis indicates that while most observational studies report a negative association between higher BMI and sexual function in postmenopausal women, the limited meta-analytic evidence does not support a significant pooled effect, suggesting that BMI may not be an independent causal factor.

Soheila Nazarpour, Masoumeh Simbar, Zahra Kiani, Reza Taherian2026-07-03
📄 medicine

Feature engineering of digital health data for machine learning prediction of COPD exacerbations in a real-world cohort

This study demonstrates that machine learning models using real-world data from the myCOPD digital platform can effectively predict COPD exacerbations with improved precision over previous models, though adding wrist-worn step-count data provided no significant additional value.

Henry M G Glyde, Alison M Blythin, Tom M A Wilkinson, Ian T Nabney, James W Dodd2026-07-03
📄 medicine

Lactate-to-Albumin Ratio as a Predictor of Short-Term Mortality in Sepsis-Associated Encephalopathy: A Dual-Cohort Retrospective Study

This dual-cohort retrospective study demonstrates that the early lactate-to-albumin ratio is an independent predictor of 28-day all-cause mortality in patients with sepsis-associated encephalopathy, suggesting its utility as a valuable biomarker for clinical risk stratification.

Liang Feng, Yang Zhu, Jun Liang, Zizhen Liu, Ji Chen, Xinyi Chen, Songtao Liu, Zhihao Chen, Junjun Wang, Feng Chen, Yayi (…)2026-07-03
📄 medicine

Investigating the prevalence of oral potentially malignant disorders among long‑distance heavy vehicle drivers

A cross-sectional screening of 3,582 Indian long-distance heavy vehicle drivers under the SCOPE initiative revealed a high prevalence of oral potentially malignant disorders, particularly white lesions, which are strongly associated with tobacco use and low health awareness, underscoring the urgent need for targeted screening and intervention strategies for this vulnerable population.

Sivaramakrishnan Muthanandam, Jananni Muthu, Bontha V Babu, Shivashankar Kengadharan2026-07-03
📄 medicine

Clinical Relevance of Serum Full-Length Glypican-3 in Unresectable Hepatocellular Carcinoma Treated with Atezolizumab and Bevacizumab

This study demonstrates that elevated baseline serum full-length glypican-3 (FL-GPC3) levels serve as an independent negative prognostic biomarker for disease control, progression-free survival, and overall survival in patients with unresectable hepatocellular carcinoma treated with atezolizumab and bevacizumab.

Naoshi Odagiri, Masaru Enomoto, Hiroko Ikenaga, Jumpei Okamura, Kanako Yoshida, Kohei Kotani, Hideto Yuasa, Ritsuzo Kozu (…)2026-07-03
📄 medicine

Effect of arteriovenous pulsed pneumatic therapy on the hemodynamic microenvironment of autologous arteriovenous fistula in hemodialysis patients

This study demonstrates that arteriovenous pulsed pneumatic therapy significantly improves the hemodynamic microenvironment of autologous arteriovenous fistulas in hemodialysis patients by increasing blood flow and wall shear stress at the anastomosis, thereby offering a promising noninvasive strategy to prevent AVF dysfunction.

Zhong-Hui Li, Jing-Tong Na, Hai-Yang Sun, Lin Liu, Xiu-Qun Cao, Chun-Xin Li, Xin Wang, Zi-Long Zhou, En-hui Guo, Yu-Lin (…)2026-07-03
📄 medicine

Development and Transportability Assessment of a Parsimonious Machine Learning Model for Predicting In-Hospital Mortality in ICU Patients with Cirrhosis and Sepsis: A MIMIC-IV and Chinese Cohort Study

This study develops and validates an interpretable, parsimonious machine learning model using early ICU data to predict in-hospital mortality in patients with cirrhosis and sepsis, demonstrating its effectiveness and transportability across both MIMIC-IV and Chinese cohorts.

Lei-Lei Zhang, Xingcheng Zhang, Li-Li Fang, Xiqun Lei, Luyao Huang, Nanbing Shan2026-07-03