📄 medicine

Comparison of methods between video raster stereography and EOS imaging in the diagnosis of adolescent idiopathic scoliosis

This prospective comparative study of 50 adolescent idiopathic scoliosis patients found that while video raster stereography (VRS) correlates significantly with EOS imaging and shows potential for radiation-free monitoring, systematic differences between the two methods prevent VRS from currently replacing EOS for diagnosis or direct clinical interchangeability.

Panagiotis Diaremes, Robert Schneider, Fee Christiane Keil, Rejane Golbach, Gerhard Oremek, David A Groneberg, Elke Hatt (…)2026-07-03
📄 medicine

The Interaction between Vitamin A and Serotonin Exhibits Sexual Dimorphism in the Core Symptoms and Neurodevelopment of Autism Spectrum Disorder: A National Multicenter Study

This national multicenter study reveals that the interaction between vitamin A deficiency and elevated serotonin levels exhibits significant sexual dimorphism, specifically modulating core symptoms and neurodevelopmental outcomes in boys with autism spectrum disorder but not in girls.

Min Guo, Dan Ai, Qian Zhang, Li Chen, Ying Dai, Hua Wei, Xiao Liu, Feiyong Jia, Yan Hao, Ling Li, Jie Zhang, Lijie Wu, X (…)2026-07-03
📄 medicine

Determining the cutoff level of body mass index for diagnosing obesity in Asian people with chronic spinal cord injury: a cross-sectional diagnostic accuracy study

This cross-sectional study involving 142 Thai individuals with chronic spinal cord injury determined that a body mass index (BMI) cutoff of 22 kg/m² is an effective screening tool for diagnosing obesity, as it correlates significantly with cardiovascular risk and aligns with optimal body fat percentage thresholds.

Sintip Pattanakuhar, Penpitcha Rojpibulstit, Jakkrit Klaphajone2026-07-03
📄 medicine

Regression of Hepatic Steatosis After Bariatric Surgery Quantified by the Ultrasound-Guided Attenuation Parameter (UGAP): A Prospective Six-Month Study

This prospective six-month study demonstrates that bariatric surgery induces a significant, early reduction in hepatic steatosis, as quantified by the ultrasound-guided attenuation parameter (UGAP), which parallels weight loss despite showing no significant correlation with BMI reduction at the individual patient level.

Ahmed Sheerali2026-07-03
📄 medicine

A Copper Metabolism-Related Gene Signature Predicts Prognosis and Therapeutic Response in Breast Cancer Based on Multi-Omics Analysis

This study establishes a robust four-gene copper metabolism-related signature that effectively stratifies breast cancer prognosis, predicts immunotherapy and chemotherapy responses, and identifies EVA1B as a potential causal therapeutic target through comprehensive multi-omics analysis and causal inference.

Weizhong Chen, Tao Chen, Yanfang Chen, Cuicai Lin, Wenhan Chen, Xiaoru Wu, Lusheng Liao, Mingyou Dong, Zhichao Fang2026-07-03
📄 medicine

Dynamic Sequential Organ Failure Assessment (SOFA) Score Trajectories as Predictors of Long-Term ICU Outcomes

This retrospective study of 1,224 ICU patients demonstrates that deteriorating SOFA score trajectories within the first week of admission are significantly associated with higher mortality rates and shorter survival compared to improving or stable trajectories, establishing these dynamic patterns as strong independent predictors of long-term outcomes.

Umut Caner Canoğlu, Fidan Yıldız Ünal, Mehrdad Sheikhvatan2026-07-03
📄 medicine

Baseline Age is Independently Associated With the Rate of Arterial Stiffening Over 7 Years in a Zambian HIV Cohort

In a 7-year longitudinal study of Zambian people living with HIV, baseline age of 50 years or older was found to be independently associated with a significantly steeper rate of arterial stiffening compared to younger patients, highlighting the need for early cardiovascular screening and management of blood pressure and BMI in routine HIV care.

Longa Kaluba, Theresa Chikopela, Sepiso K Masenga, Benson M Hamooya, Fastone Goma, Wilbroad Mutale, Katongo H Mutengo2026-07-03
📄 medicine

Antimicrobial resistance in Burundi: a mixed-methods protocol for assessing   prevalence, risk factors and association with infection prevention and control

This mixed-methods study protocol outlines a cross-sectional investigation at Kamenge Teaching Hospital in Burundi to assess the high prevalence (41.2%) of multidrug-resistant bacterial infections and identify key risk factors, including prior antibiotic exposure, self-medication, and prolonged hospitalization, to guide improved infection control and empirical therapy strategies.

NIYONKURU Prosper, NIYONSABA Vestine2026-07-03