📄 medicine
Physiological comparison of high-flow oxygen via endotracheal tube and T-piece strategies during spontaneous breathing trials: a randomized crossover study
This randomized crossover study demonstrates that high-flow oxygen delivered via an endotracheal tube, particularly with smaller expiratory ports and higher flow rates, generates beneficial pressure-dependent physiological effects—including improved lung volume, oxygenation, and reduced dynamic stress—while maintaining inspiratory effort comparable to post-extubation levels, positioning it as a promising alternative to T-piece strategies for spontaneous breathing trials.
Shan-Shan Xu, Rui-Zhi Zhang, Jun-Tong Liu, Lin Wang, Meng-Xue Hou, Xu An, Ming-Yue Miao, Hong-Liang Li, Yue-Fu Wang, Jia (…)2026-07-02