5683 papers
This prospective study demonstrates that ultrasound elastography, particularly when combining quantitative strain ratio analysis with qualitative assessment, significantly enhances the diagnostic accuracy and specificity for differentiating benign from malignant thyroid nodules compared to conventional TIRADS-based ultrasonography alone.
This study of 119 Iranian patients demonstrates that admission and in-hospital laboratory parameters, specifically elevated creatinine, decreased oxygen saturation, and low potassium levels, serve as valuable prognostic indicators for mortality in acute paraquat poisoning, offering a practical alternative where specific urinary testing is unavailable.
This cross-sectional study of 346 Chinese older stroke patients utilized latent profile analysis and network analysis to identify three distinct physical resilience subgroups—low externally dependent, moderate balanced, and high proactive optimistic—revealing that education, comorbidities, and psychosocial factors predict profile membership while highlighting coping and lifestyle adjustment as core bridge nodes for targeted nursing interventions.
This study presents PER301, a scalable, non-absorbable nanomedicine that integrates enzyme shielding, mucoadhesive retention, and biomimetic activation to achieve a 69-fold increase in digestive potency and fully restore lipid absorption in pancreatic insufficiency models, offering a stable and precise alternative to conventional oral enzyme therapies.
In a retrospective study of patients with intracranial hemorrhage on factor Xa inhibitors, andexanet alfa was associated with a higher rate of significant hemorrhage growth compared to 4-factor prothrombin complex concentrate, while both treatments showed similar outcomes regarding neurological deterioration, thromboembolic events, and mortality.
This prospective cohort study in Papua New Guinea demonstrates that modifying the WHO-prequalified Xpert HPV test by restricting detection to the eight most oncogenic HPV types and applying stricter cycle threshold cut-offs significantly improves the specificity and positive predictive value for detecting high-grade cervical pre-cancer among women living with HIV, offering a pragmatic, single-visit "screen-and-treat" solution for low-resource settings.
This retrospective propensity score-matched study demonstrates that continuous calcimimetic use in dialysis patients receiving erythropoiesis-stimulating agents within a target hemoglobin range is significantly associated with lower all-cause mortality, particularly among elderly patients with high ESA doses, cardiovascular disease, low body mass, or inflammation.
This 2024 cross-sectional study of 33 hearing-impaired students at Alamal School in Kassala, Sudan, reveals a high prevalence of ophthalmic disorders—particularly refractive errors and posterior segment abnormalities—and identifies significant statistical associations between these eye conditions, parental consanguinity, and the etiology of hearing loss, underscoring the need for integrated visual and auditory health assessments.
This study demonstrates that sub-chronic oral exposure to four widely used herbicides (glyphosate, dicamba, S-metolachlor, and cyhalofop-butyl) induces significant multi-organ toxicity in male rats, with cyhalofop-butyl exhibiting the most severe hepatorenal and hematological damage compared to the other formulations.
This qualitative descriptive study of 24 Chinese parents of preterm infants reveals that the transition from NICU to home involves a shift from monitored safety to "calibrated caregiving," where families must learn to interpret uncertain infant cues and manage fragmented care tasks, suggesting that nursing support should be restructured around staged transition touchpoints, embodied rehearsal, and accessible post-discharge connections rather than simple information handovers.