5683 papers
This cross-sectional study of 120 Lebanese Class II Division 1 patients reveals that mandibular retrognathism is universally characterized by reduced ramal height and body length regardless of gender, highlighting the clinical necessity to distinguish between positional and dimensional subtypes to guide appropriate treatment strategies.
This case report demonstrates that local infiltration anesthesia combined with S-ketamine is a viable and effective alternative for cesarean delivery in a high-risk parturient with diaphragmatic hernia and severe scoliosis, where conventional neuraxial and general anesthesia pose significant technical challenges or safety risks.
This paper reports a novel compound heterozygous ATM variant in a Colombian family presenting with a variant ataxia-telangiectasia phenotype characterized by chorea, ataxia, and a high burden of malignancies, highlighting the critical importance of early diagnosis for effective oncologic surveillance and genetic counseling.
This single-center study of 103 children in high-altitude Tibet characterizes pediatric urolithiasis by dense stones, frequent upper urinary tract involvement, and inadequate fluid intake, while identifying positive preoperative urine culture, prolonged operative time, and the lack of negative-pressure suction sheath use as independent predictors of postoperative fever.
This study analyzes 2014–2023 data to reveal that while pulmonary tuberculosis incidence and mortality in Mainland China have generally declined, the disease exhibits significant spatial clustering in the northwest and humid, economically developed regions, with incidence negatively associated with health expenditure and medical staffing but positively linked to illiteracy rates.
This study reveals that from 1999 to 2024, age-adjusted mortality rates among US adults aged 65 and older with coexisting neoplasms and cardiac arrhythmias increased substantially, with the highest burdens observed in males, non-Hispanic White individuals, the oldest age groups, and residents of the South and non-metropolitan areas, highlighting urgent needs for targeted cardio-oncology strategies and equitable care.
This study utilizes multimodal MRI to demonstrate that in Parkinson's disease, the locus coeruleus exerts a substantial functional compensatory influence on the substantia nigra, a mechanism supported by complementary network-level effects and distinct patterns of neuromelanin loss compared to mild cognitive impairment.
This study demonstrates that water-ethanolic extracts of *Rosmarinus officinalis* and *Hygrophila spinosa* from the Nilgiri Hills are safe, potent antioxidants and immunomodulators, with *R. officinalis* showing superior immunostimulatory potential in reversing cyclophosphamide-induced immunosuppression in mice.
This retrospective study of over 16,000 patients reveals that the COVID-19 pandemic had a heterogeneous impact on cancer staging trends across different lineages, causing significant upstaging in lung, prostate, and colorectal cancers while paradoxically showing downstaging in breast cancer, with no significant changes observed for pancreatic and gastric cancers.
This study demonstrates that a novel sublingual bivalent vaccine combining the fusion protein PspA-C-CPE with Alcaligenes lipid A elicits robust, long-lasting, and non-invasive protective immunity against both Streptococcus pneumoniae respiratory infections and Clostridium perfringens enterotoxin-mediated foodborne illnesses in mice.