📄 medicine

Improving National Drug List Harmonization Through an Eight-Pattern Analysis of WHO ATC/DDD Classifications

This paper introduces an 8-Pattern Classification Framework based on WHO ATC/DDD data to identify and resolve discrepancies in national drug lists, specifically addressing cases where single molecules have multiple classifications or inconsistencies in administration routes and defined daily doses to improve global harmonization and reporting accuracy.

Mohammad Javad Rajabi, Mitra Mahmoudi-Meymand, Mehrdad Vesali-Sharif2026-07-02
📄 medicine

Angiographic Classification of Vascularized Retained Products of Conception and Uterine Artery Embolization Outcomes: A Single-Center Study of 106 Patients

This single-center study of 106 patients demonstrates that proximal uterine artery embolization with gelatin sponge torpedoes is a safe and effective treatment for hemorrhagic highly vascularized retained products of conception, while validating a novel 4-stage angiographic classification that correlates with clinical outcomes and may facilitate non-invasive pre-procedural stratification via MRI.

Marie LEROUX, Julien GHELFI, Emeric GREMEN, Alexandre BUISSON, Aurelie DELOUCHE, Mathieu RODIERE, Yann TEYSSIER, Mathieu (…)2026-07-02
📄 medicine

Adjunctive extended platelet-rich fibrin enhances clinical and esthetic outcomes of the VISTA technique in RT1 gingival recession: A randomized controlled clinical trial

This randomized controlled trial demonstrates that combining extended-platelet-rich fibrin (e-PRF) with the VISTA technique yields significantly superior clinical and esthetic outcomes, including greater root coverage and soft tissue thickness, compared to the VISTA technique alone for treating RT1 gingival recession at six months.

POOJA Nagarajan, raison thomas, rucha shah, triveni mg, hiral karwa2026-07-02
📄 medicine

Beyond Pain Relief: Impact of Therapeutic Strategies on Health-Related Quality of Life in Endometriosis Using the EHP-30

In a monocentric cross-sectional study of 80 Tunisian women, surgical management, particularly complete excision, was found to yield the greatest improvement in health-related quality of life as measured by the EHP-30, supporting a multidimensional and individualized approach to endometriosis care.

Arij Youssef, Amal Alimi, Abdeljalil Khelifi, Sassi Bouguizan2026-07-02
📄 medicine

Peer-Led Examination Simulation Reshapes Psychophysiological and Emotional State Profiles During Problem-Based Medical Learning

This study demonstrates that embedding a peer-led examination simulation into problem-based learning for medical students induces a more salient and educationally valued psychophysiological state characterized by increased autonomic arousal and reduced boredom, without compromising motivation, thereby validating psychophysiological metrics as tools for optimizing instructional design.

Morris Gellisch, Thorsten Schäfer2026-07-02
📄 medicine

Ascorbic acid as an adjunct therapy for hyporesponsive anemia in Erythropoietin-treated hemodialysis patients: A systematic review and meta-analysis

This systematic review and meta-analysis of ten randomized trials suggests that ascorbic acid supplementation modestly improves hemoglobin levels, transferrin saturation, and erythropoietin responsiveness in hyporesponsive hemodialysis patients by enhancing iron mobilization, although the overall evidence certainty is low and safety data remain unclear.

España De la Rosa Valdez, Montserrat Villa Sanchez, Salma Alejandra Beltran Covarrubias, Angelo Magallanes Bajana, Aleja (…)2026-07-02
📄 medicine

Disparities in Central Cord Syndrome: A Registry-Based Retrospective Cohort Study on surgical intervention and recovery across race from a national spinal cord injury database

This retrospective cohort study of a national spinal cord injury database found that while African American patients with Central Cord Syndrome presented with higher rates of bladder incontinence, their functional recovery outcomes measured by FIM and ASIA scores at discharge and one year were comparable to those of Caucasian patients, suggesting that previously reported racial disparities in functional impairment may stem from factors other than the core recovery metrics captured in this dataset.

Elvis Vidal, Christopher McGinley, Noor Malik, Damirez Fossett2026-07-02
📄 medicine

Postoperative disease-free survival prediction based on MRI radiomics combined with clinicopathological factors in locally advanced rectal cancer

This study demonstrates that a combined model integrating pretreatment MRI-derived radiomics features with clinicopathological factors significantly improves the prediction of postoperative disease-free survival and risk stratification for patients with locally advanced rectal cancer compared to using either approach alone.

Chun kang Liu, Jingjuan Liu, Ning Zhang, Qi Xiao, Chentong Wang, Fuze Cong, Huadan Xue, Guole Lin2026-07-02
📄 medicine

Tailored Personas for Palliative Care Decision-Making Among Caregivers of Patients with End-Stage Heart Failure: A Qualitative Study

This qualitative study utilized user persona methodology to identify four distinct caregiver profiles—proactive, anxious-conflicted, resistant-avoidant, and isolated-helpless—based on their palliative care decision-making characteristics, thereby providing a theoretical foundation for developing personalized decision-support interventions for caregivers of patients with end-stage heart failure.

Qi Wang, Na Liu, Hang Wang, Leying Li, Ye Fei, Weiying Zhang2026-07-02
📄 medicine

Risk Factors and Clinical Characteristics of Rhegmatogenous Retinal Detachment after Implantable Collamer Lens Implantation in High Myopia: a matched case-control study

This matched case-control study identifies preoperative retinal degeneration and early postoperative intraocular pressure elevation as independent risk factors for rhegmatogenous retinal detachment following implantable collamer lens surgery in high myopia, underscoring the need for comprehensive preoperative assessment and strict perioperative IOP management.

Liduo Pan, Jian Deng, Meng Wang, Fei Liu, Xiaobei Chen, Yonghao Li2026-07-02