6041 papers
This study evaluates public awareness of newborn screening and hereditary disorders in India through a nationwide survey, revealing significant knowledge gaps that necessitate policy-driven strategies and targeted educational initiatives to improve early detection and reduce the long-term health burden.
This prospective cohort study of Chinese middle-aged and older adults reveals that persistent and worsening depressive symptom trajectories are associated with more than double the risk of developing incident cardiometabolic multimorbidity compared to low and decreasing symptom patterns.
This study demonstrates that puberty is associated with a significant and accelerated decline in kidney function (eGFR) among children with chronic kidney disease, including those with early-stage disease, a trend observed across both sexes and not solely attributable to pubertal changes in muscle mass.
This retrospective study demonstrates that a modified disposable surgical drape significantly outperforms conventional reusable cloth drapes in robotic radical prostatectomy by reducing weight, lowering costs by 49%, and eliminating peri-incisional bacterial contamination.
This prospective cohort study of 6,534 Chinese adults demonstrates that nine C-reactive protein-triglyceride-glucose index (CTI)-derived adiposity phenotypes are significantly associated with the risk of incident cardiovascular-liver-metabolic multimorbidity, with the CTI-BMI index showing the strongest and most robust predictive performance.
A cross-sectional survey of 82 primary care providers and endocrinologists reveals significant gaps in their ability to accurately interpret key elements of ophthalmology notes for diabetic retinopathy, highlighting the need for standardized documentation to improve inter-specialty care coordination.
ProToxNet is a novel framework that integrates proteome-wide drug–protein binding predictions with tissue-specific gene expression to accurately predict tissue-stratified adverse events for both known and novel drugs, demonstrating strong generalization and clinical validity across multiple benchmarks.
This retrospective cohort study of 865 hip replacement patients found that perioperative administration of acetate-buffered balanced crystalloid solution (SPMCG) was significantly associated with a reduced risk of postoperative myocardial injury within 3 and 7 days compared to non-SPMCG use.
This study analyzes the 2022 Liberia Malaria Indicator Survey data to reveal significant spatial heterogeneity in under-five malaria prevalence, identifying southern and southeastern hotspots driven by rainfall, vegetation, and water proximity, thereby advocating for geographically differentiated control strategies.
This study analyzed data from the China Health and Retirement Longitudinal Study (CHARLS) and the US Health and Retirement Study (HRS) to find that while rapid kidney function decline showed a trend toward increased hip fracture risk in older adults, the association was not statistically significant in either cohort.