6064 papers
This mixed-methods cohort study in conflict-affected Myanmar demonstrates that a nurse-led, community-based immunisation programme successfully re-established access and achieved full immunisation in 50% of zero-dose children, highlighting the critical role of community engagement and sustained follow-up despite significant logistical and security challenges.
This study of Northern Chinese patients reveals that early-onset type 2 diabetes is characterized by a more aggressive metabolic profile and a disproportionately higher age-standardized burden of microvascular complications, particularly nephropathy and retinopathy, compared to late-onset disease, underscoring the need for earlier, comprehensive risk assessment that includes factors like serum uric acid.
This scoping review of 57 studies reveals that while DBT Skills Training groups are widely implemented in outpatient settings to treat borderline personality disorder, there is substantial heterogeneity in their delivery across various parameters, indicating flexible adaptability but leaving uncertainty regarding the most effective implementation approaches.
This qualitative study involving 11 healthcare professionals and a consumer representative found that a dynamic consent platform (CoGenT) could effectively address time barriers and enhance understanding in precision oncology by complementing, rather than replacing, face-to-face discussions, provided it is tailored to specialty-specific needs and prioritizes privacy and usability.
This study presents an oral nanotherapeutic platform based on phytocarbon dots derived from *Dianthus superbus* that alleviates hepatic fibrosis by acting as molecular glues to induce the ubiquitination and proteasomal degradation of the upregulated protein ENO1, thereby suppressing the PI3K/AKT-Smad3 pathway.
This cross-sectional study of 333 pregnant women in the post-pandemic period reveals a high prevalence of thyroid dysfunction and increased autoimmunity, with prior SARS-CoV-2 infection linked to lower TSH levels but vaccination showing no significant impact on thyroid parameters.
A national cross-sectional survey of Turkish hematologists reveals that while AI adoption in clinical and research settings is rapidly increasing, it is significantly outpacing structured training, institutional governance, and data safety protocols, highlighting an urgent need for hematology-specific policies and education to ensure responsible integration.
In a retrospective study of patients with paroxysmal atrial fibrillation and abnormal body weight treated with direct oral anticoagulants, women exhibited significantly higher fibrinogen and D-dimer levels than men, while endothelial and platelet-derived hemostatic biomarkers remained comparable between sexes.
This study demonstrates that engineered M13 phage nanobots, functionalized with a tumor-targeting antibody and loaded with Rose Bengal photosensitizers, effectively reduce neoplastic burden in both murine xenografts and human ovarian cancer models by precisely delivering the payload to EGFR-expressing cells for light-triggered photoablation.
This cluster-randomised trial in Ghana demonstrates that five rounds of community-wide dihydroartemisinin–piperaquine mass drug administration significantly reduced malaria parasite prevalence by 94%, lowered reinfection risk, and improved haemoglobin outcomes in a moderate-to-high transmission setting without serious adverse events.