📄 medicine

Turkish Adaptation of the Supportive and Palliative Care Indicators Tool (SPICT): A Validity and Reliability Study

This study demonstrates that the Turkish adaptation of the Supportive and Palliative Care Indicators Tool (SPICT-TR) is a valid and reliable instrument for identifying patients with palliative care needs in Türkiye, showing high internal consistency and strong agreement with physician clinical assessments.

Öznur Kalmuk Çetin, Hande Ileri, Yasemin Kılıç Öztürk2026-07-06
📄 medicine

Early-life anti-infective exposure and subsequent neurodevelopmental disorders: a nationwide propensity-matched cohort study

This nationwide propensity-matched cohort study in South Korea found that early-life severe or recurrent infections, quantified by frequent hospitalizations and cumulative exposure to antibacterial and antimycotic agents, are associated with an increased risk of subsequent neurodevelopmental and psychiatric disorders, whereas antiviral exposure showed no such positive association.

Yunhye Oh, Suhyun Han, Vin Ryu2026-07-06
📄 medicine

Clinical and laboratory characteristics and factors associated with mortality in meningococcal infection at Military Hospital 175, Vietnam: a retrospective case series

This retrospective study at Military Hospital 175 in Vietnam identifies impaired consciousness, shock, metabolic derangement, coagulopathy, organ dysfunction, and a low CSF-to-blood glucose ratio as key clinical and laboratory factors associated with in-hospital mortality among patients with meningococcal infection.

Phap Bui Van, Giang Vu Son2026-07-06
📄 medicine

Research on the Evaluation System of Discipline Competitiveness in County-level Public Hospitals Based on Resource-Based Theory

This study constructs and validates a scientifically sound evaluation index system for discipline competitiveness in county-level public hospitals based on Resource-Based Theory, utilizing the Delphi method to establish a framework of 2 first-level, 6 second-level, and 36 third-level indicators that can effectively guide clinical discipline construction.

Ping Wu, Tingting Li, Huihui Zuo2026-07-06
📄 medicine

Diminished ovarian reserve is associated with impaired oocyte morphology and reduced ART outcomes in women under 35 years: a prospective cohort study

This prospective cohort study demonstrates that in women under 35, diminished ovarian reserve is associated not only with reduced oocyte yield but also with significantly impaired oocyte morphology, lower fertilization and embryo quality rates, and decreased clinical pregnancy outcomes compared to women with normal ovarian reserve.

Fatemeh Dehghanpour, Nooshin Hatamizadeh, Hossein Fallahzadeh, Saeideh Dashti2026-07-06
📄 medicine

Association of Anemia Severity and Lactate Dehydrogenase With Clinical Complications in Adults With Sickle Cell Disease: A Panamanian Cohort

In a Panamanian cohort of adults with sickle cell disease, lower hemoglobin levels were associated with a reduced risk of avascular necrosis, while higher lactate dehydrogenase levels were linked to an increased risk of acute chest syndrome and avascular necrosis, highlighting the distinct yet overlapping contributions of anemia severity and hemolysis to specific clinical complications.

Niko Diaz García, María Mantilla, Fernando Carrillo, Lorena Ordoñez, Germán Espino2026-07-06
📄 medicine

30-Day Mortality Risk Prediction Model for Intracerebral Hemorrhage Patients Combined with Albumin Infusion Characteristics

This study developed and validated a Logistic Regression model using MIMIC-IV and MIMIC-III data to predict 30-day mortality in intracerebral hemorrhage patients with albumin infusion characteristics, achieving strong predictive performance (AUC > 0.80) and providing interpretable insights via SHAP analysis to guide clinical risk assessment and treatment optimization.

Xiangjun Chen, Zhigang Huang2026-07-06
📄 medicine

Antimicrobial Resistance Patterns in Uropathogens Isolated from Type 2 Diabetic Patients in a Tertiary Hospital, Ghana: A Cross-Sectional Approach

This cross-sectional study at Sunyani Teaching Hospital, Ghana, reveals a 27.6% prevalence of uropathogens among Type 2 diabetic patients, identifies Enterococcus species as the most common isolate, highlights specific risk factors and clinical markers for infection, and confirms that while multidrug resistance is prevalent, meropenem, amikacin, and levofloxacin remain highly effective treatment options.

George Owusu, Meshack Antwi-Adjei, Ibrahim Nana Boakye, Akosua Ankomaa Owusu Peprah, Mohammed Sherifa, Jones Ofori-Amoah2026-07-06