📄 medicine

Exogenous Prolactin Receptor Antagonism Attenuates Post-thyroidectomy Retching-like Behavior by Inhibiting Dopaminergic Neuronal Activation in the Nucleus Tractus Solitarius

This study demonstrates that exogenous antagonism of the prolactin receptor in the nucleus tractus solitarius attenuates post-thyroidectomy retching-like behavior by inhibiting the activation of dopaminergic neurons, thereby identifying a novel neuroendocrine pathway and therapeutic target for postoperative nausea and vomiting.

Jian-Lei Ge, Xiao-Yi Ma, Jing-Yu Hui, Hong–Lian Duan, Meng–Yue Wang, Yue Fu, Ting–Ting Feng, Hu–Wei Duan, Yi Zhang, Li–M (…)2026-07-03
📄 medicine

Teaching African Traditional Health Knowledge and Practices in Undergraduate Nursing Education: A National Survey of South African Nurse Educators

A national survey of South African nurse educators reveals a significant gap between the recognized importance of African traditional health knowledge and practices and their minimal, inconsistent, and largely theoretical integration into undergraduate nursing curricula, highlighting an urgent need for structured educational reform to better prepare nurses for pluralistic healthcare systems.

Mabitja Moeta, Fhumulani Mavis Mulaudzi2026-07-03
📄 medicine

Perceived Mental Health Service Priorities among Social Service Personnel in South Korea: An Importance–Performance Analysis by Depression Severity

This study utilizes Importance–Performance Analysis on 201 South Korean social service personnel to reveal that mental health service priorities and unmet needs vary significantly by depression severity, advocating for a shift from uniform support to a coordinated, severity-responsive framework with strengthened referral pathways.

Jong-Eun Park, Yujin Kim, Young-Eun Son2026-07-03
📄 medicine

Endovascular Treatment of Chronic and Acute on Chronic Mesenteric Ischaemia: Should Only the SMA Be the Primary Target for Revascularisation?

This retrospective study of 29 patients suggests that endovascular revascularization for chronic and acute-on-chronic mesenteric ischemia is safe and feasible with similar symptomatic relief outcomes regardless of whether the coeliac trunk or superior mesenteric artery is the primary target.

Helen Foss, Ahmed ElShiekh, Alok Tiwari, Maciej Juszczak, Arul Ganeshan, Ruth Hartley2026-07-03
📄 medicine

Comparing Intermittent Fasting, Clean Ketogenic Diet, and Their Combined Effects on Body Composition, Cardiometabolic Markers, and Metabolic Health: A Three-Arm Randomized Pre-Post Study

This three-arm randomized pre-post study found that while a clean ketogenic diet alone produced the greatest weight loss and cardiometabolic improvements, combining it with intermittent fasting provided additional, independent benefits for glycemic control and grip strength.

Angie MacKewn, Julie Floyd, Todd Sherman, Alison Ellis, Anna Dunn, Diana Sanford2026-07-03
📄 medicine

Dexmedetomidine attenuates methamphetamine-induced hyperthermia and hyperlocomotion by modulating monoamine dynamics in the anterior hypothalamus

Dexmedetomidine attenuates methamphetamine-induced hyperthermia and hyperlocomotion in rats primarily through α2A-adrenergic receptor mechanisms by suppressing the release of dopamine and noradrenaline in the anterior hypothalamus, suggesting its potential as a therapeutic intervention for severe methamphetamine intoxication.

Tsuyoshi Okada, Seiji Obi, Katsutoshi Shioda, Chikara Yonekawa, Shiro Suda2026-07-03
📄 medicine

Implementation and Evaluation of a Mobile App to Support Communication in Paediatric Palliative Home Care: Results of a Multicentre Observational Pilot Study

This multicentre observational pilot study demonstrates that the co-designed PalliDoc Mobile App is a sustainable and beneficial addition to paediatric palliative home care in Germany, showing high adoption rates, good usability, and effective asynchronous communication, though synchronous video consultations had no measurable impact on care delivery.

Merlin J. Deckers, Klara Sogl, Sarmad Ghori, Rebekka Hocher, Sebastian Kruempelmann, Cornelia Messerschmidt, Heidi Moell (…)2026-07-03