Exogenous Prolactin Receptor Antagonism Attenuates Post-thyroidectomy Retching-like Behavior by Inhibiting Dopaminergic Neuronal Activation in the Nucleus Tractus Solitarius
This study demonstrates that exogenous antagonism of the prolactin receptor in the nucleus tractus solitarius attenuates post-thyroidectomy retching-like behavior by inhibiting the activation of dopaminergic neurons, thereby identifying a novel neuroendocrine pathway and therapeutic target for postoperative nausea and vomiting.