📄 medicine

Complete reperfusion benefits cognitive recovery in MCA occlusion after patients receiving thrombectomy

This multicenter retrospective study demonstrates that achieving complete reperfusion following mechanical thrombectomy for middle cerebral artery occlusion significantly improves long-term cognitive recovery and serves as an independent protective factor against cognitive impairment, without increasing major complications.

Ke Yang, Yanbing Wen, Changqing Chen, Ji Li, Dongxu Qiu2026-07-03
📄 medicine

Metabolic hyperferritinaemia (MHF) in Bariatric Surgery Candidates: Prevalence and Cross-Sectional Associations with Liver Function and Metabolic Markers

This cross-sectional study of 695 bariatric surgery candidates reveals that metabolic hyperferritinaemia affects 18.51% of patients, with a significantly higher prevalence in males, and is strongly associated with abnormal liver function, glycolipid metabolism, and hematological indicators, suggesting that targeted iron regulation could help manage obesity-related metabolic complications.

Huajiang Liu, Liqin Zhang, Cunchuan Wang, Zhiyong Dong, Songhao Hu2026-07-03
📄 medicine

Depression as an Independent Predictor of Cost-Related Medication Nonadherence Among U.S. Adults

Based on a 2024 analysis of over 450,000 U.S. adults, depression is an independent predictor of cost-related medication nonadherence, doubling the odds of missing prescribed drugs due to cost even after adjusting for socioeconomic factors, with income and insurance status emerging as the strongest additional drivers of this disparity.

Oluwapelumi Odubunmi, Adedapo Ogunlewe, Idris Idenyi, Abdullah Adeniji-Bello2026-07-03
📄 medicine

Nomophobia in the Digital Era: An Ayurvedic Perspective on Mental Health and Holistic Management

This paper examines the growing public health issue of nomophobia through an Ayurvedic lens, proposing that integrating traditional holistic practices like Sattvajaya Chikitsa and Rasayana with modern interventions offers a sustainable and culturally acceptable strategy for managing digital addiction and restoring mental balance.

Gajender J, Nikita Sharma, Narind Khajuria, Mahesh Vyas2026-07-03
📄 medicine

The Severity Paradox of Metropolitan Traffic Trauma: Geographic Administrative Boundaries as an Independent Predictor of Anatomical Injury Severity

This retrospective cohort study of over 5,000 traffic crash patients in Taiwan reveals that geographic administrative boundaries (specifically New Taipei City versus Taipei City) serve as a potent independent predictor of major trauma severity, even after controlling for physiological status, thereby highlighting the need for region-specific triage protocols that prioritize location and age over traditional physiological triggers.

Mon-Chun Chen, Chun-Man Kuo, Ching-Lin Chen2026-07-03
📄 medicine

Polygenic Risk Scores in the Early Detection of Cancer and Autoimmune Disease in Patients with Non-Specific Symptoms: Insights from the SCAN Cohort

This study of the SCAN cohort demonstrates that while polygenic risk scores offer modest incremental value for stratifying cancer risk in patients with non-specific symptoms, they show strong, consistent associations with various autoimmune diseases, suggesting a more immediate role for PRS integration in autoimmune diagnostics compared to cancer screening.

Dimitrios V. Vavoulis, Anthony Cutts, Carla Giner-Delgado, Stephen Ash, Georgetta Ciuban, Helene Dreau, Francoise Howe (…)2026-07-03
📄 medicine

Concurrent validity of fixed-frame vs handheld dynamometer assessment of isometric neck strength

This study found that fixed-frame and handheld dynamometers show only moderate to weak correlations in assessing isometric neck strength among female rugby players, indicating that these testing protocols should not be used interchangeably and that a single system should be consistently applied for longitudinal monitoring.

Bradley James Hornsey, Nicola Sewry, Martin Jordaan, Candice MacMillan2026-07-03
📄 medicine

The relationship between sexual function and body mass index in menopause: a systematic review and meta-analysis

This systematic review and meta-analysis indicates that while most observational studies report a negative association between higher BMI and sexual function in postmenopausal women, the limited meta-analytic evidence does not support a significant pooled effect, suggesting that BMI may not be an independent causal factor.

Soheila Nazarpour, Masoumeh Simbar, Zahra Kiani, Reza Taherian2026-07-03
📄 medicine

Feature engineering of digital health data for machine learning prediction of COPD exacerbations in a real-world cohort

This study demonstrates that machine learning models using real-world data from the myCOPD digital platform can effectively predict COPD exacerbations with improved precision over previous models, though adding wrist-worn step-count data provided no significant additional value.

Henry M G Glyde, Alison M Blythin, Tom M A Wilkinson, Ian T Nabney, James W Dodd2026-07-03
📄 medicine

Lactate-to-Albumin Ratio as a Predictor of Short-Term Mortality in Sepsis-Associated Encephalopathy: A Dual-Cohort Retrospective Study

This dual-cohort retrospective study demonstrates that the early lactate-to-albumin ratio is an independent predictor of 28-day all-cause mortality in patients with sepsis-associated encephalopathy, suggesting its utility as a valuable biomarker for clinical risk stratification.

Liang Feng, Yang Zhu, Jun Liang, Zizhen Liu, Ji Chen, Xinyi Chen, Songtao Liu, Zhihao Chen, Junjun Wang, Feng Chen, Yayi (…)2026-07-03