📄 medicine

Lactate-to-Albumin Ratio as a Predictor of Short-Term Mortality in Sepsis-Associated Encephalopathy: A Dual-Cohort Retrospective Study

This dual-cohort retrospective study demonstrates that the early lactate-to-albumin ratio is an independent predictor of 28-day all-cause mortality in patients with sepsis-associated encephalopathy, suggesting its utility as a valuable biomarker for clinical risk stratification.

Liang Feng, Yang Zhu, Jun Liang, Zizhen Liu, Ji Chen, Xinyi Chen, Songtao Liu, Zhihao Chen, Junjun Wang, Feng Chen, Yayi (…)2026-07-03
📄 medicine

Investigating the prevalence of oral potentially malignant disorders among long‑distance heavy vehicle drivers

A cross-sectional screening of 3,582 Indian long-distance heavy vehicle drivers under the SCOPE initiative revealed a high prevalence of oral potentially malignant disorders, particularly white lesions, which are strongly associated with tobacco use and low health awareness, underscoring the urgent need for targeted screening and intervention strategies for this vulnerable population.

Sivaramakrishnan Muthanandam, Jananni Muthu, Bontha V Babu, Shivashankar Kengadharan2026-07-03
📄 medicine

Clinical Relevance of Serum Full-Length Glypican-3 in Unresectable Hepatocellular Carcinoma Treated with Atezolizumab and Bevacizumab

This study demonstrates that elevated baseline serum full-length glypican-3 (FL-GPC3) levels serve as an independent negative prognostic biomarker for disease control, progression-free survival, and overall survival in patients with unresectable hepatocellular carcinoma treated with atezolizumab and bevacizumab.

Naoshi Odagiri, Masaru Enomoto, Hiroko Ikenaga, Jumpei Okamura, Kanako Yoshida, Kohei Kotani, Hideto Yuasa, Ritsuzo Kozu (…)2026-07-03
📄 medicine

Effect of arteriovenous pulsed pneumatic therapy on the hemodynamic microenvironment of autologous arteriovenous fistula in hemodialysis patients

This study demonstrates that arteriovenous pulsed pneumatic therapy significantly improves the hemodynamic microenvironment of autologous arteriovenous fistulas in hemodialysis patients by increasing blood flow and wall shear stress at the anastomosis, thereby offering a promising noninvasive strategy to prevent AVF dysfunction.

Zhong-Hui Li, Jing-Tong Na, Hai-Yang Sun, Lin Liu, Xiu-Qun Cao, Chun-Xin Li, Xin Wang, Zi-Long Zhou, En-hui Guo, Yu-Lin (…)2026-07-03
📄 medicine

Development and Transportability Assessment of a Parsimonious Machine Learning Model for Predicting In-Hospital Mortality in ICU Patients with Cirrhosis and Sepsis: A MIMIC-IV and Chinese Cohort Study

This study develops and validates an interpretable, parsimonious machine learning model using early ICU data to predict in-hospital mortality in patients with cirrhosis and sepsis, demonstrating its effectiveness and transportability across both MIMIC-IV and Chinese cohorts.

Lei-Lei Zhang, Xingcheng Zhang, Li-Li Fang, Xiqun Lei, Luyao Huang, Nanbing Shan2026-07-03
📄 medicine

Comparison of methods between video raster stereography and EOS imaging in the diagnosis of adolescent idiopathic scoliosis

This prospective comparative study of 50 adolescent idiopathic scoliosis patients found that while video raster stereography (VRS) correlates significantly with EOS imaging and shows potential for radiation-free monitoring, systematic differences between the two methods prevent VRS from currently replacing EOS for diagnosis or direct clinical interchangeability.

Panagiotis Diaremes, Robert Schneider, Fee Christiane Keil, Rejane Golbach, Gerhard Oremek, David A Groneberg, Elke Hatt (…)2026-07-03
📄 medicine

The Interaction between Vitamin A and Serotonin Exhibits Sexual Dimorphism in the Core Symptoms and Neurodevelopment of Autism Spectrum Disorder: A National Multicenter Study

This national multicenter study reveals that the interaction between vitamin A deficiency and elevated serotonin levels exhibits significant sexual dimorphism, specifically modulating core symptoms and neurodevelopmental outcomes in boys with autism spectrum disorder but not in girls.

Min Guo, Dan Ai, Qian Zhang, Li Chen, Ying Dai, Hua Wei, Xiao Liu, Feiyong Jia, Yan Hao, Ling Li, Jie Zhang, Lijie Wu, X (…)2026-07-03
📄 medicine

Determining the cutoff level of body mass index for diagnosing obesity in Asian people with chronic spinal cord injury: a cross-sectional diagnostic accuracy study

This cross-sectional study involving 142 Thai individuals with chronic spinal cord injury determined that a body mass index (BMI) cutoff of 22 kg/m² is an effective screening tool for diagnosing obesity, as it correlates significantly with cardiovascular risk and aligns with optimal body fat percentage thresholds.

Sintip Pattanakuhar, Penpitcha Rojpibulstit, Jakkrit Klaphajone2026-07-03