6270 papers
This cross-sectional study involving 142 Thai individuals with chronic spinal cord injury determined that a body mass index (BMI) cutoff of 22 kg/m² is an effective screening tool for diagnosing obesity, as it correlates significantly with cardiovascular risk and aligns with optimal body fat percentage thresholds.
This prospective six-month study demonstrates that bariatric surgery induces a significant, early reduction in hepatic steatosis, as quantified by the ultrasound-guided attenuation parameter (UGAP), which parallels weight loss despite showing no significant correlation with BMI reduction at the individual patient level.
This study establishes a robust four-gene copper metabolism-related signature that effectively stratifies breast cancer prognosis, predicts immunotherapy and chemotherapy responses, and identifies EVA1B as a potential causal therapeutic target through comprehensive multi-omics analysis and causal inference.
This retrospective study of 1,224 ICU patients demonstrates that deteriorating SOFA score trajectories within the first week of admission are significantly associated with higher mortality rates and shorter survival compared to improving or stable trajectories, establishing these dynamic patterns as strong independent predictors of long-term outcomes.
In a 7-year longitudinal study of Zambian people living with HIV, baseline age of 50 years or older was found to be independently associated with a significantly steeper rate of arterial stiffening compared to younger patients, highlighting the need for early cardiovascular screening and management of blood pressure and BMI in routine HIV care.
This mixed-methods study protocol outlines a cross-sectional investigation at Kamenge Teaching Hospital in Burundi to assess the high prevalence (41.2%) of multidrug-resistant bacterial infections and identify key risk factors, including prior antibiotic exposure, self-medication, and prolonged hospitalization, to guide improved infection control and empirical therapy strategies.
This study introduces ResNet-CLAC, a novel deep learning framework incorporating multi-scale attention and gated cross-layer fusion, which achieves state-of-the-art accuracy in predicting microsatellite instability from gastrointestinal cancer histology slides, offering a cost-effective and interpretable alternative to traditional diagnostic methods.
This propensity score-matched cohort study found that immediate postnatal cardiac surgery for selected neonates with critical congenital heart disease is feasible and does not increase perioperative risks compared to conventional neonatal surgery, while potentially reducing the rate of post-discharge unplanned reinterventions.
This study demonstrates that postoperative complication severity is a major driver of hospital costs following colon cancer surgery, with emergency procedures incurring significantly higher expenses than elective ones across all complication grades, particularly for severe (Clavien-Dindo Grade IV) complications.
This pilot study demonstrates that an interpretable 30-feature Ridge regression model, trained on leakage-free data, significantly improves fetal birth weight prediction accuracy and standardizes performance across sonographers of varying experience levels compared to the traditional Hadlock 4 formula.