📄 medicine

The impact of educational intervention based on Cognitive-Behavioral Therapy on fear of childbirth in pregnant women; a quasi-experimental intervention study

This quasi-experimental study conducted in Qom, Iran, demonstrates that an eight-session cognitive-behavioral therapy educational program significantly reduced fear of childbirth and improved knowledge and attitudes among pregnant women compared to those receiving routine prenatal care.

Siamak Mohebi, Ehsan Vesali-Monfared, Abolfazl Mohammadbeigi, Bentolhoda Kolahkaj, Maryam Yousefi, Ashraf Khoramirad2026-07-03
📄 medicine

DNA-Inspired Symbolic Encoding with Adaptive Block-level Hybrid CGR-FCGR Features for Osteoporosis Progression Detection

This paper proposes a novel framework for osteoporosis screening using plain radiographs that combines entropy-guided adaptive block division, DNA-inspired symbolic encoding with CGR/FCGR features, and a hybrid HTGCA-Net deep learning model to achieve high accuracy in both binary and multiclass classification tasks.

Lipika Dinda, Jitesh Pradhan, Manish Raj, Tapan Kumar Dey2026-07-03
📄 medicine

Neutrophil-to-Lymphocyte Ratio and Mean Platelet Volume in Relation to Pressure Ulcer Stages in a Palliative Care Unit: A Retrospective Single-Center Study

This retrospective study of non-oncological palliative inpatients found that admission neutrophil-to-lymphocyte ratio and mean platelet volume were not independently associated with pressure ulcer presence or stage, a null result attributed to the confounding effect of pre-existing chronic wounds in a referral-based setting and highlighting clinical risk scores as the primary actionable correlates.

Mustafa Gökhan Bayram, Dinçer Fırat Şeker2026-07-03
📄 medicine

Implementation and effectiveness of a telemedicine platform among patients with rare diseases and their caregivers: A non-randomized controlled study

This non-randomized controlled study found that while a telemedicine platform for rare disease patients and caregivers did not significantly improve quality of life or depression compared to in-person care, it substantially increased treatment satisfaction and reduced healthcare costs, despite facing technical and administrative implementation barriers.

Youngshin Joo, Jisoo Baek, Jong-Hee Chae, Soo Yeon Kim, Seungbok Lee, Young Jin Kwon2026-07-03
📄 medicine

Clinical Characteristics and Predisposing Factors in Candida auris Infection: A Retrospective Analysis

This retrospective study of eight immunocompromised patients in Jiangxi Province characterizes *Candida auris* infections as occurring predominantly in individuals with invasive procedures and prior broad-spectrum antibiotic exposure, often co-occurring with Gram-negative bacilli and associated with poor outcomes despite antifungal treatment.

Qingqing Xu, Jing Li, Huaming Guo, Minyu Liu, Xia Chen, Jiaxin Tu, Ling Zeng, Xiu-Hua Kang2026-07-03
📄 medicine

The Impact of City Administrative Levels on Disability Among Patients with Central Nervous System Disorders

This multicenter cross-sectional study of over 8,000 Chinese patients with central nervous system disorders reveals that residing in higher-tier cities independently predicts more severe disability, a macro-environmental risk that is significantly exacerbated for low socioeconomic status individuals but buffered for those with high socioeconomic status.

Qiulin LI, Ankang Liu, Zhenhui Wen, Ruixue Ye, Shinan Liu, Aidong Li, Yulong Wang2026-07-03
📄 medicine

Combined intramedullary nailing and plate fixation for femoral shaft nonunion enables earlier weight-bearing.

This retrospective comparative study demonstrates that combining intramedullary nailing with plate fixation for femoral shaft nonunion significantly shortens the time to authorized and effective full weight-bearing compared to isolated exchange nailing, without compromising union rates or increasing septic complications.

Guillaume Boiteux, Emile Dobelle, Pascal Maman, Richard Volpi, Xavier Flecher, Marie Le baron2026-07-03
📄 medicine

Clinical and genetic characteristics of Nagashima-type palmoplantar keratoderma: A single-centre cross-sectional study

This single-centre study of 85 patients with Nagashima-type palmoplantar keratoderma characterizes the disease's clinical heterogeneity, including its association with atopic dermatitis and renal abnormalities, and expands the known genotypic spectrum of *SERPINB7* while identifying specific demographic and genetic patterns.

Zhongtao Li, Xinyu Cheng, Sheng Wang2026-07-03
📄 medicine

The Effect of Docosahexaenoic Acid on Cognitive Function and the Meduation of Ferroptosis Biomarkers in Older Adults : A Randomized Controlled Trial

This randomized controlled trial demonstrates that daily docosahexaenoic acid (DHA) supplementation significantly improves cognitive function in older Chinese adults with mild cognitive impairment, an effect that is partially mediated by the modulation of ferroptosis-related biomarkers.

Xinze Han, Jing Yuan, Zimo Shi, Xian Cai, Ziyan Lou, Xuan Chen, Yu Tian, Fei Ma2026-07-03