6270 papers
This retrospective study demonstrates that obesity, particularly severe obesity, is a strong independent predictor of *Helicobacter pylori* transformation into the coccoid form and increased crypt colonization, suggesting a need for tailored diagnostic and eradication strategies in obese patients.
This study introduces a novel 3D-printed Partial Occlusion Device (POD) that serves as a stable, reusable, and fiber-free alternative to cotton-tip applicators for microsurgical anastomosis revision, demonstrating comparable efficacy and safety while offering surgeons improved stability and control in a rat femoral artery model.
This case report describes a rare instance of *Actinotignum sanguinis*-associated prosthetic aortic valve infective endocarditis in a urologically compromised elderly man, highlighting the diagnostic challenges of slow-growing anaerobes, the necessity of early surgical intervention despite pending microbiological confirmation, and the complex management of postoperative mixed shock leading to patient recovery.
This case report describes a rare instance of low-grade pancreatic intraepithelial neoplasia mimicking a branch-duct IPMN in a patient with long-standing systemic lupus erythematosus, highlighting the diagnostic limitations of conventional imaging and the severe, life-threatening postoperative complications arising from surgery in immunosuppressed patients.
This meta-research study reveals that highly influential musculoskeletal and sports physiotherapy trials frequently lack complete exercise dosage reporting and often prescribe parameters inconsistent with physiological rationale, thereby compromising the replicability and potential efficacy of these interventions.
This retrospective study of 297 culture-confirmed infection episodes at a Rwandan tertiary hospital reveals that multidrug-resistant pathogens, particularly in urinary tract infections, are prevalent among cancer patients and often resistant to commonly prescribed empirical antibiotics like ceftriaxone, highlighting an urgent need for locally informed stewardship protocols and improved data capture.
This paper illustrates how integrating Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE) with clinician-graded CTCAE data in a Phase I acute myeloid leukemia trial provides a more comprehensive assessment of patient symptom burden and tolerability to inform dose-escalation decisions.
Using panel data from Chinese cities and interpretable machine learning, this study reveals that while urban eco-sanitation conditions have improved, they do not automatically translate into enhanced health service supply capacity due to a mismatch in resource allocation and fiscal mechanisms, necessitating an integrated governance framework to bridge the gap.
This study presents a sensitive, cost-effective liquid biopsy assay that measures protease activity in plasma extracellular vesicles to accurately detect diffuse large B-cell lymphoma, predict treatment response, and monitor disease relapse.
This study demonstrates that European LeukemiaNet-defined clinical signs and symptoms serve as superior prognostic markers for predicting thrombosis and disease progression in polycythemia vera patients treated with ruxolitinib, outperforming conventional risk stratification methods.