📄 medicine

Maternal-Child Healthcare Continuity and Zero-Dose Status Among Children in Nigeria: A Pooled DHS Analysis, 2013–2024

This pooled analysis of Nigeria's 2013–2024 Demographic and Health Surveys reveals a strong dose-response relationship between maternal antenatal care attendance and reduced zero-dose status among children, suggesting that strengthening maternal-child healthcare continuity is a critical strategy for improving immunization equity.

Nuhu Idris Itopa, Muhammad Idris Aliyu2026-07-02
📄 medicine

Assessing Renal Calcifications and Dysfunctions in Primary Hyperparathyroidism: Clinical and Biochemical Predictors

In a retrospective study of 386 patients with primary hyperparathyroidism, male sex and markedly elevated parathyroid hormone levels were identified as independent predictors of renal calcifications, while renal dysfunction was associated with advancing age, the presence of calcifications, and higher levels of calcium, phosphorus, and parathyroid hormone.

Ayushi Singhal, Subhash Chandra Yadav, Anjali Mishra, Ayushi Chak, Ambica Tandon, Shivendra Verma, Ayush Gupta, Preeti D (…)2026-07-02
📄 medicine

Development and Validation of a Multidimensional Ultrasound-based Gastrointestinal Congestion Score (GICS) for Predicting Persistent Acute Gastrointestinal Injury in Critically Ill Patients

This study developed and validated a novel, organ-specific Gastrointestinal Congestion Score (GICS) using multidimensional ultrasound parameters, which demonstrated superior predictive accuracy for persistent acute gastrointestinal injury in critically ill patients compared to traditional systemic congestion scores by effectively identifying "occult" splanchnic stasis.

Sai Qi Wu, Hai Jun Zhi, Xiao Jie Meng, Jian Wang, Dong Ming Liu, Ya Ning Zhao, Sen Lin, Lian Kai Hou, Li Mei Du, Yong Li2026-07-02
📄 medicine

Understanding the Enablers, Constraints, and Sustainability of State-Church Health Partnerships in Ghana: A Sustainability of Innovation Framework embedded Qualitative Study 

This qualitative study utilizing the Sustainability of Innovation Framework reveals that the sustainability of state-church health partnerships in Ghana relies less on formal policy frameworks and more on adaptive practices, social embeddedness, and faith-based resilience that navigate systemic inequities and financial vulnerabilities.

Joseph Atta Amankwah, Emmanuel Kwasi Afriyie, Justine Ti-Baliana Martha Naab, Francisca Kuukua Egyaim, Enoch Nana Kwaben (…)2026-07-02
📄 medicine

First-trimester thyroid function, haemoglobin and fasting glucose as predictors of gestational diabetes mellitus and its impact on pregnancy outcomes: a multiethnic retrospective cohort study

This multiethnic retrospective cohort study identifies first-trimester total triiodothyronine, haemoglobin, and fasting plasma glucose as independent predictors of gestational diabetes mellitus, while also determining that specific first-trimester biomarkers can forecast cesarean delivery rates among affected patients in a high-altitude population.

Wenlu Wang, Liping Yang, Chunye He, Gutian Zhao, Yaowu Chen, Xiaoji Li2026-07-02
📄 medicine

Prevalence of Urinary Tract Infection and Associated Risk Factors Among Pregnant Women Attending Selected Hospitals, Hargeisa, Somaliland

This study conducted in Hargeisa, Somaliland, reveals a high prevalence of urinary tract infections (78.2%) among pregnant women, identifying recurrent UTIs, anemia, poor hygiene, and inadequate antenatal care attendance as significant associated risk factors.

Mustafe Yusuf Said, Khalid Mohamed Nur, Mohamed Abdirahman Wacays, Sa'ad Ahmed Abdiwali, Abdijaliil Mohamed Farah2026-07-02
📄 medicine

Furosemide initiation during norepinephrine infusion and proximal hemodynamic destabilization: a target trial emulation in MIMIC-IV with external validation in eICU-CRD

This target trial emulation using MIMIC-IV and eICU-CRD data reveals that initiating furosemide during active norepinephrine infusion is associated with a significant increase in proximal hemodynamic destabilization and acute kidney injury without a detectable short-term mortality benefit, suggesting a need for careful timing in vasopressor-dependent patients.

Lujun Shao, Cheng Xu, Huiyu Tai, Yue Li2026-07-02
📄 medicine

Predicting Prognosis of Locoregionally Advanced Nasopharyngeal Carcinoma Using Machine Learning Models Based on Plasma Proteomics : A retrospectively registered Study

This retrospective study identifies and validates plasma BAK1 as a novel machine learning-derived biomarker that effectively predicts short-term treatment response and long-term survival outcomes in patients with locoregionally advanced nasopharyngeal carcinoma.

Yuyi Li, Chao Tan, Xiaoyu Chen, Weichang Zhu, Cuihong Jiang, Lili He, Shuai Xiao, Changgen Fan, Xu Ye, Qi Zhao, Wenqiong (…)2026-07-02
📄 medicine

Relieve pain or improve function? Tenodesis should be selected on the basis of demand

This study concludes that both arthroscopic intertubercular groove and suprapectoral tenodesis combined with rotator cuff repair effectively treat small supraspinatus tears with long head of biceps tendon lesions, though the choice between techniques should be guided by patient-specific demands given the early functional advantages of the intertubercular approach and the distinct pathological characteristics of the tendon zones.

Yue Geng, Xusheng Bo, Jiangtao Gao, Zhihua Wang, Ye Tian, Yi Zheng, Zhuangdai Zhang, Jiangtao Dong2026-07-02