📄 medicine

Peer-Led Examination Simulation Reshapes Psychophysiological and Emotional State Profiles During Problem-Based Medical Learning

This study demonstrates that embedding a peer-led examination simulation into problem-based learning for medical students induces a more salient and educationally valued psychophysiological state characterized by increased autonomic arousal and reduced boredom, without compromising motivation, thereby validating psychophysiological metrics as tools for optimizing instructional design.

Morris Gellisch, Thorsten Schäfer2026-07-02
📄 medicine

Ascorbic acid as an adjunct therapy for hyporesponsive anemia in Erythropoietin-treated hemodialysis patients: A systematic review and meta-analysis

This systematic review and meta-analysis of ten randomized trials suggests that ascorbic acid supplementation modestly improves hemoglobin levels, transferrin saturation, and erythropoietin responsiveness in hyporesponsive hemodialysis patients by enhancing iron mobilization, although the overall evidence certainty is low and safety data remain unclear.

España De la Rosa Valdez, Montserrat Villa Sanchez, Salma Alejandra Beltran Covarrubias, Angelo Magallanes Bajana, Aleja (…)2026-07-02
📄 medicine

Disparities in Central Cord Syndrome: A Registry-Based Retrospective Cohort Study on surgical intervention and recovery across race from a national spinal cord injury database

This retrospective cohort study of a national spinal cord injury database found that while African American patients with Central Cord Syndrome presented with higher rates of bladder incontinence, their functional recovery outcomes measured by FIM and ASIA scores at discharge and one year were comparable to those of Caucasian patients, suggesting that previously reported racial disparities in functional impairment may stem from factors other than the core recovery metrics captured in this dataset.

Elvis Vidal, Christopher McGinley, Noor Malik, Damirez Fossett2026-07-02
📄 medicine

Postoperative disease-free survival prediction based on MRI radiomics combined with clinicopathological factors in locally advanced rectal cancer

This study demonstrates that a combined model integrating pretreatment MRI-derived radiomics features with clinicopathological factors significantly improves the prediction of postoperative disease-free survival and risk stratification for patients with locally advanced rectal cancer compared to using either approach alone.

Chun kang Liu, Jingjuan Liu, Ning Zhang, Qi Xiao, Chentong Wang, Fuze Cong, Huadan Xue, Guole Lin2026-07-02
📄 medicine

Tailored Personas for Palliative Care Decision-Making Among Caregivers of Patients with End-Stage Heart Failure: A Qualitative Study

This qualitative study utilized user persona methodology to identify four distinct caregiver profiles—proactive, anxious-conflicted, resistant-avoidant, and isolated-helpless—based on their palliative care decision-making characteristics, thereby providing a theoretical foundation for developing personalized decision-support interventions for caregivers of patients with end-stage heart failure.

Qi Wang, Na Liu, Hang Wang, Leying Li, Ye Fei, Weiying Zhang2026-07-02
📄 medicine

Risk Factors and Clinical Characteristics of Rhegmatogenous Retinal Detachment after Implantable Collamer Lens Implantation in High Myopia: a matched case-control study

This matched case-control study identifies preoperative retinal degeneration and early postoperative intraocular pressure elevation as independent risk factors for rhegmatogenous retinal detachment following implantable collamer lens surgery in high myopia, underscoring the need for comprehensive preoperative assessment and strict perioperative IOP management.

Liduo Pan, Jian Deng, Meng Wang, Fei Liu, Xiaobei Chen, Yonghao Li2026-07-02
📄 medicine

Positional and Dimensional Characteristics of the mandible In Lebanese Class II Division 1 Skeletal Malocclusion Patients (Cross-sectional Study)

This cross-sectional study of 120 Lebanese Class II Division 1 patients reveals that mandibular retrognathism is universally characterized by reduced ramal height and body length regardless of gender, highlighting the clinical necessity to distinguish between positional and dimensional subtypes to guide appropriate treatment strategies.

Alaa K. Dokmak, Nadia El Harouni, Aly Osman2026-07-02
📄 medicine

Local infiltration anesthesia combined with S-ketamine for cesarean delivery in a parturient with diaphragmatic hernia and severe scoliosis: a case report

This case report demonstrates that local infiltration anesthesia combined with S-ketamine is a viable and effective alternative for cesarean delivery in a high-risk parturient with diaphragmatic hernia and severe scoliosis, where conventional neuraxial and general anesthesia pose significant technical challenges or safety risks.

Wenqin Zhou, Dong Luo2026-07-02
📄 medicine

A novel ATM variant in a Colombian family with chorea-ataxia syndrome: implications for an early diagnosis

This paper reports a novel compound heterozygous ATM variant in a Colombian family presenting with a variant ataxia-telangiectasia phenotype characterized by chorea, ataxia, and a high burden of malignancies, highlighting the critical importance of early diagnosis for effective oncologic surveillance and genetic counseling.

VIVIANA ALEXANDRA MARTINEZ-VILLOTA, Malco Rossi, Lucely Ortega-Bolaños2026-07-02
📄 medicine

Clinical and Epidemiological Characteristics of Pediatric Urolithiasis in a High‑Altitude Region of Tibet: A Single‑Center Study of 103 Children

This single-center study of 103 children in high-altitude Tibet characterizes pediatric urolithiasis by dense stones, frequent upper urinary tract involvement, and inadequate fluid intake, while identifying positive preoperative urine culture, prolonged operative time, and the lack of negative-pressure suction sheath use as independent predictors of postoperative fever.

Weiyuan Li, Keqiang Li, Zhijin Zhang, Yuke Zhang, Weijiang Li, Jianbing Guo, Cuomu Si Lang, Xiaoqian Ding, Dunzhu Ci Ren (…)2026-07-02