📄 Category

medicine

6270 papers

📄 medicine

Andexanet alfa versus Prothrombin Complex Concentrate for Direct Anticoagulation Reversal in Intracranial Hemorrhage: A Comparative Effectiveness Study

In a retrospective study of patients with intracranial hemorrhage on factor Xa inhibitors, andexanet alfa was associated with a higher rate of significant hemorrhage growth compared to 4-factor prothrombin complex concentrate, while both treatments showed similar outcomes regarding neurological deterioration, thromboembolic events, and mortality.

Hemangi Rajpal, Deepika Dilip, Audrey Huang, Jenny Yang, William Liu, Nimrod Gozum, Hannah Young, Gular Mammadli, Nicole (…)2026-07-01
📄 medicine

Point-of-care HPV DNA testing for the early detection and treatment of cervical pre-cancer among women living with HIV in Papua New Guinea: a prospective clinical cohort study

This prospective cohort study in Papua New Guinea demonstrates that modifying the WHO-prequalified Xpert HPV test by restricting detection to the eight most oncogenic HPV types and applying stricter cycle threshold cut-offs significantly improves the specificity and positive predictive value for detecting high-grade cervical pre-cancer among women living with HIV, offering a pragmatic, single-visit "screen-and-treat" solution for low-resource settings.

Sauk Joyce, Michaela Riddell, Joy Tongela, Fredah Koluk, Hari Lialu, Grace Tan, Robert Jones, Arthur Elijah, Josephine G (…)2026-07-01
📄 medicine

Continuous calcimimetic use with erythropoiesis-stimulating agent co-administration within a target hemoglobin range is associated with lower mortality in dialysis patients

This retrospective propensity score-matched study demonstrates that continuous calcimimetic use in dialysis patients receiving erythropoiesis-stimulating agents within a target hemoglobin range is significantly associated with lower all-cause mortality, particularly among elderly patients with high ESA doses, cardiovascular disease, low body mass, or inflammation.

Kazuyoshi Okada, Manabu Tashiro, Daisuke Hara, Shimpei Araki, Ryo Mochizuki, Tomoko Inoue, Takahiro Kuragano, Jun Minaku (…)2026-07-01
📄 medicine

Pattern of Eye Diseases Among Hearing Impaired Students of Alamal School for The Deaf - Kassala 2024

This 2024 cross-sectional study of 33 hearing-impaired students at Alamal School in Kassala, Sudan, reveals a high prevalence of ophthalmic disorders—particularly refractive errors and posterior segment abnormalities—and identifies significant statistical associations between these eye conditions, parental consanguinity, and the etiology of hearing loss, underscoring the need for integrated visual and auditory health assessments.

Fatima Ahmed Mohamed Sharif Sharif, Israa Fadlalla Elbasheir Rabih Rabih2026-07-01
📄 medicine

From monitored safety to calibrated caregiving: a qualitative descriptive study of parents' transition from neonatal intensive care unit to home with preterm infants

This qualitative descriptive study of 24 Chinese parents of preterm infants reveals that the transition from NICU to home involves a shift from monitored safety to "calibrated caregiving," where families must learn to interpret uncertain infant cues and manage fragmented care tasks, suggesting that nursing support should be restructured around staged transition touchpoints, embodied rehearsal, and accessible post-discharge connections rather than simple information handovers.

Kejimu Sunzi, Qin Huang, Yiluo Xu, Yang Gao, Ting Zeng, Hui Luo, Quanmin Deng2026-07-01
📄 medicine

Women’s perinatal trajectories from high-risk pregnancy to the discharge of their premature infant from the NICU: A qualitative study

This qualitative study of 34 women utilizes Mishel's Uncertainty in Illness Theory to reveal how persistent and evolving uncertainty is perceived, appraised, and managed across the perinatal trajectory from high-risk pregnancy to NICU discharge, highlighting the critical roles of maternal identity and social support in shaping coping strategies.

Sun-Hee Kim, Hye Young Min, Mi-Kyung Park, Bu Youn Kim2026-07-01
📄 medicine

Recruitment Inefficiency in Public Hospitals Under the Single-Position Application Model and the Potential of a Parallel Volunteer Mechanism

This study identifies structural inefficiencies in China's single-position hospital recruitment model as a key driver of vacancies in critical specialties and demonstrates through a counterfactual analysis that a parallel volunteer mechanism could theoretically achieve full position completion by enabling cross-hospital candidate matching.

Zhizhou Xiong, Yan Li, Meng Li, Fan Yang, Yunjie Shi, Yuan Liao2026-07-01
📄 medicine

A functional durability framework for insecticide-treated nets (ITNs): integrating fabric and insecticide durability through mathematical modelling of longitudinal field data from Tanzania

This paper presents a functional durability framework for insecticide-treated nets (ITNs) that integrates mathematical modeling of longitudinal field data from Tanzania to demonstrate that while physical fabric degradation increases mosquito entry, residual insecticidal activity often remains sufficient to maintain overall entomological effectiveness, suggesting that future product design should prioritize insecticide performance alongside fabric durability to ensure sustained public health impact.

Sarah J Moore, Dennis J Massue, Watson S Ntabaliba, Olivier J T Briet, Thomas A Smith2026-07-01