📄 medicine

Anatomy-Driven Automated Subsegmentation of Pelvic and Proximal Femoral CT into Clinically Relevant Subregions and Landmark

This study presents and validates a rule-based pipeline in 3D Slicer that automatically converts pelvic and proximal femoral CT scans into clinically relevant subregions and landmarks, significantly reducing manual workload while maintaining high anatomical accuracy for normal adult anatomy.

Mohammed Rashed, Hatem Alabdulrahman, Simon D. Westfechtel, Frank Hildebrand, Daniel Truhn2026-07-01
📄 medicine

Effects of Maternal Diabetes on Respiratory Outcomes of Moderately Preterm Infants: Have We Made Progress?

Despite advancements in maternal diabetes management, moderately preterm infants of diabetic mothers continue to experience higher respiratory morbidity, including increased surfactant use and prolonged oxygen requirements, compared to their non-diabetic counterparts.

Hilal Yildiz Atar, Nadine-Stella Achenjang, Samantha Kauffman, Rachel Hyzny Hyzny, Merlin Pinto, Christopher Nau, Rita R (…)2026-07-01
📄 medicine

Detected case growth and outcome heterogeneity during the 2026 Bundibugyo virus disease outbreak in the Democratic Republic of the Congo and Uganda

This retrospective analysis of the 2026 Bundibugyo virus outbreak in the DRC and Uganda demonstrates that source-traced official aggregate data can reveal critical operational signals regarding detected case growth, heterogeneous outcomes, and response bottlenecks, provided these findings are interpreted with explicit data-quality safeguards rather than as definitive causal estimates.

Tambe Elvis Akem, Eta Calvin Oben2026-07-01
📄 medicine

Clinical Readiness of Machine-Learning Risk Models in Non-Variceal Upper Gastrointestinal Bleeding: A Systematic Review and Network Meta-Analysis

Although machine learning models appear to outperform the Glasgow-Blatchford Score in discrimination, a systematic review and network meta-analysis of 26 studies concludes that current evidence is too limited and of low certainty to support replacing established clinical scores with ML for routine management of non-variceal upper gastrointestinal bleeding.

Hyuk Lee, Yang Won Min, Hyosoon Yoo, Sehun Kim, Tae Jun Kim2026-07-01
📄 medicine

Person-Centredness in Dementia Diagnosis & Detection: A Scoping Review

This scoping review reveals that while person-centred care is recognized as vital for dementia diagnosis, current literature offers limited and conceptually unclear guidance that disproportionately focuses on clinical assessment and disclosure while neglecting longitudinal support, emerging technologies, and the co-production of care with people living with dementia.

Matthew Y Guo, Ana Diaz, Dianne Gove, Frank Jessen, Charles P Khoury, Ryan E Wiley, Youssef H El-Hayek2026-07-01
📄 medicine

Spatial epidemiology and multilevel determinants of enteric fever in the India-Bangladesh-Myanmar border region

This study analyzes passive surveillance data from Mizoram, India (2022–2025) to reveal a high enteric fever burden of 920 per 100,000 person-years, identifying that while cases cluster in urban centers, village-level determinants like poor WASH infrastructure and inadequate healthcare access significantly drive incidence and hospitalization, thereby underscoring the urgent need for strengthened surveillance, vaccination, and WASH investments in the India-Bangladesh-Myanmar border region.

Lalfakzuala Pautu, Pooja Telugu Prakash, Vanlalrengpuia Chinzah, Pachuau Lalmalsawma, Van Lalsawma, Eric Zomawia, Zorin (…)2026-07-01
📄 medicine

Early Postoperative Complications after Decompressive Craniectomy for Pediatric Severe Traumatic Brain Injury

This retrospective study of 83 pediatric patients with severe traumatic brain injury undergoing decompressive craniectomy reveals that early postoperative neurosurgical complications, particularly secondary hemorrhage, occurred in nearly 40% of cases and were significantly associated with higher intraoperative intracranial pressure and longer preoperative durations of elevated pressure.

Zhanna Semenova, Denis Bragin, Evgenii Rogozhin, Vladimir Lukyanov, Semen Meshcheryakov2026-07-01
📄 medicine

Immunomodulatory effects of telitacicept plus mycophenolate mofetil on B‑cell subsets in patients with systemic lupus erythematosus

This study demonstrates that combining telitacicept with mycophenolate mofetil effectively restores B-cell homeostasis in systemic lupus erythematosus patients by downregulating BLyS and pro-inflammatory cytokines, directly inhibiting age-associated B-cell differentiation, and promoting regulatory B-cell recovery, resulting in superior immunomodulatory effects compared to mycophenolate mofetil monotherapy.

Chengqiang Zhang, Min Zhang, Dongmei Li, Lina Li, Mengyao Zhang, Gailian Zhang2026-07-01
📄 medicine

Direct Anterior Approach Is Associated with Superior Postoperative Sexual Function Compared with Anterolateral Approach in Men Undergoing Total Hip Arthroplasty: A Prospective Cohort Study

In a prospective cohort study of men undergoing total hip arthroplasty, the direct anterior approach was associated with superior postoperative erectile function and greater pain reduction compared to the anterolateral approach, although the latter group reported greater improvements in overall physical and psychological well-being.

Miklós Szabó, Jozef Almási, Igor Bartl, Boris Šteno2026-07-01