📄 Category

medicine

6270 papers

📄 medicine

Investigating the effect of antibiotic-containing niosomes on amoxicillin- and metronidazole- resistant bacteria isolated from dental abscesses

This study demonstrates that amoxicillin- and metronidazole-loaded niosomes, characterized by controlled drug release and enhanced stability, significantly reduce the minimum inhibitory and bactericidal concentrations of these antibiotics against resistant *Enterococcus faecalis* and *Staphylococcus epidermidis* isolated from dental abscesses, suggesting their potential as an effective alternative treatment for drug-resistant oral infections.

Zahra Tavasoli Kejani, Nafiseh Sadat Naghavi, Reyhaneh Jafari2026-07-01
📄 medicine

Blastocyst quality does not affect live birth outcomes in frozen-thawed single blastocyst transfer among patients with thin endometrium: A retrospective cohort study

This retrospective cohort study of 1,041 cycles reveals that while blastocyst quality significantly influences live birth rates in patients with normal endometrium, it has no predictive value for live birth outcomes in patients with thin endometrium (<8 mm) undergoing frozen-thawed single blastocyst transfer.

Tengfei Wang, Yaojia Zhang, Lijun Peng, Yun Le, Sheng Yang, Mengyi Zhu2026-07-01
📄 medicine

Frontoparietal Cortical Activation during VR-based Prism Adaptation in Stroke Patients with Unilateral Spatial Neglect: an fNIRS study

This study utilized functional near-infrared spectroscopy (fNIRS) to demonstrate that virtual reality-based prism adaptation in stroke patients with unilateral spatial neglect engages compensatory bilateral parietal and right dorsolateral prefrontal cortical circuits, providing preliminary neuroimaging evidence for its potential neuroplastic effects.

Ahyun Kim, Won Kee Chang, Sungmin Cho, Jongseung Lee, Nam-Jong Paik, Han-Jeong Hwang, Won-Seok Kim2026-07-01
📄 medicine

How about the surgical efficacy of unicompartmental knee arthroplasty for “mid-medial tibial plateau osteoarthritis” ?

This study demonstrates that while patients with mid-medial tibial plateau osteoarthritis (MTPO) experience slower early functional recovery compared to those with anteromedial knee osteoarthritis (AKO) following mobile-bearing unicompartmental knee arthroplasty, both groups achieve comparable mid- to long-term outcomes with no increased risk of major complications, supporting MTPO as a favorable indication for the procedure.

Junbin Zhang, Ziyu Zhang, Kaihua Liu, Yuan Sang, Yichun Xu, Ping Li, Hui Yao2026-07-01
📄 medicine

Prevalent versus incident progressive supranuclear palsy: An analysis of the frequencies of neuropathological and clinical features at U.S. Alzheimer's Disease Research Centers indicate a relatively common tauopathy of aging

This study analyzes data from 37 U.S. Alzheimer's Disease Research Centers to reveal that incident progressive supranuclear palsy (PSP) pathology is surprisingly common in cognitively normal older adults and differs significantly from prevalent PSP in terms of age at death, clinical presentation, and specific tau pathology features.

Benjamin J Cushing, Ryan K. Shahidehpour, Erin L. Abner, Gregory A. Jicha, Janna M. Neltner, Madeline K. Breig, Kailen L (…)2026-07-01
📄 medicine

Toxicities following treatment for melanoma: defining components of a comprehensive survivorship program

This population-level study of over 30,000 Ontario melanoma patients reveals that while toxicities peak during treatment, patients receiving adjuvant therapy experience persistently higher rates of moderate-to-severe symptoms and unmet mental health needs in early survivorship, highlighting the urgent need for comprehensive survivorship programs tailored to this growing cohort.

Valerie A Francescutti, Anastasia Gayowsky, Gregory R Pond, Hsien Seow, Elaine McWhirter, Linda M Lee, Elie Isenberg-Grz (…)2026-07-01
📄 medicine

Which is the Best Threshold for Asymmetry Indices for Single Subjects 5-ht1a Receptor Pet Studies in Temporal Lobe Epilepsy? a Discriminant Analysis Validation

This study validates that using a threshold of the control mean plus two standard deviations for asymmetry indices in 5-HT1A receptor PET scans, particularly when combined with partial volume correction, provides the highest accuracy (100%) for identifying epileptogenic foci in single subjects with temporal lobe epilepsy.

Giampiero Giovacchini, William Theodore2026-07-01
📄 medicine

Brainstem Infarction Following Resection of a Cerebellopontine Angle Epidermoid Cyst with Normal Intraoperative Neurophysiological Monitoring: A Case Report

This case report describes a rare instance of acute ventral brainstem infarction following the resection of a cerebellopontine angle epidermoid cyst that occurred despite normal intraoperative neurophysiological monitoring, thereby revealing a critical limitation of current monitoring technologies and emphasizing the necessity of immediate postoperative pupillary examination.

Changqing Li, Er-qing Chai, Ke Shuai, Jianglian Chen2026-07-01
📄 medicine

Leveraging a Novel Combination of Spatial and School Data to Explore Associations between Neighborhood Trauma and Social Determinants of Health in Philadelphia Schools

This study introduces a Neighborhood Adversity Index (NAI) to map neighborhood trauma in Philadelphia and demonstrates that schools in high-trauma areas face significantly worse attendance, physical activity, safety perceptions, and economic conditions, validating the NAI as a critical tool for targeting trauma-informed interventions.

Gabriella M McLoughlin, Angel G Smith, Krista Schroeder2026-07-01
📄 medicine

Contextual assessment of health system alignment with National Standards for Cancer Survivorship Care in the American Southeast

This study assessed a large American Southeast health system's alignment with National Standards for Cancer Survivorship Care using mixed methods, revealing that while informants reported meeting roughly half of the standards, significant variability in implementation and a low survey response rate highlight the need for targeted strategies to address identified barriers and improve consistency.

Shirley Bluethmann, Stephanie Bunch, Chandylen Nightingale, Alana Willis, Beth York, Beth Fisher, Sarah Birken, Rachel Z (…)2026-07-01