📄 medicine

Factors Associated with Deaths within Income Restricted and Supportive Housing in Denver, Colorado: A Retrospective Cohort Study

This retrospective cohort study of 255 adults in Denver's income-restricted and supportive housing found that overdose was the leading cause of death and that lack of substance use treatment, alongside specific racial demographics, was significantly associated with an increased risk of preventable mortality.

Kathleen Joseph, Beth Gregory, Jason Haukoos, Austin Jones, Jessica Rast, Sarah A. Stella, Joshua A. Barocas, Joanna Leo (…)2026-07-01
📄 medicine

First-Tier Genomic Newborn Screening at Population Scale: End-of-Study Outcomes and the Dominant Cardiomyopathy Reporting Dilemma – The BabyDetect Experience

The BabyDetect study demonstrates that population-scale first-tier genomic newborn screening in Belgium is feasible and highly accepted, successfully identifying treatable conditions missed by conventional methods while highlighting the critical need for strict reporting criteria to avoid the clinical utility of low-penetrance dominant cardiomyopathy findings.

Kristine Hovhannesyan, Tamara Dangouloff, Valérie JACQUEMIN, Myriam MNI, Davood MASHHADIZADEH, Nadege Hennuy, Vincent Ri (…)2026-07-01
📄 medicine

Knowledge, Information Needs, Perceived Barriers, and Facilitators to Antenatal Exercise Among Primiparous Pregnant Women in Sri Lanka: A Qualitative Exploratory Study

This qualitative study of 19 primiparous pregnant women in Sri Lanka reveals that while they hold positive views toward antenatal exercise, their participation is significantly hindered by knowledge gaps and barriers, highlighting the critical need for improved health education, reliable information sources, and structured exercise programs to facilitate engagement.

Sepalage Nilanthi Chathurika, Chathura Rathnayake, Deepika Indumathie Nanayakkara, Sampath Udaya BandaraThennakoon, Abey (…)2026-07-01
📄 medicine

Biopsy-Anchored Clinical Phenotyping and Renal Outcomes in Phosphate Nephropathy: A 47-Patient Cohort Study

This study of 47 patients demonstrates that phosphate nephropathy following oral sodium phosphate exposure frequently leads to persistent kidney dysfunction and a delayed AKI-to-CKD trajectory, with clinically probable cases showing comparable long-term outcomes to biopsy-confirmed disease, suggesting the condition is substantially underrecognized in routine practice.

Meryem Keleş, Aysel Çolak, Burak Aslum, Emre Çankaya, Müge Üzerk Kibar, Şimal Köksal Cevher, Fatih Yılmaz, Ezgi Coşkun Y (…)2026-07-01
📄 medicine

Comparison of the Diagnostic Reliability of ChatGPT in Letournel–Judet Acetabulum Fracture Classification Based on Judet Radiographs According to Orthopaedic Residents

This study demonstrates that ChatGPT-4o exhibits fundamentally inadequate diagnostic reliability and negligible agreement with expert standards for classifying Letournel–Judet acetabular fractures, performing significantly worse than orthopaedic residents and thus failing as a viable decision-support tool for pelvic trauma.

Muhammed Kilic, Ahmet Ozgur Yildirim, Ibrahim Alper Yavuz, Fatih Inci, Erman Ceyhan, Yakup Kahve, Tahsin Aydin, Ozdamar (…)2026-07-01
📄 medicine

An EHR Data Passport for Renal-Risk AI: Cross-Database Transportability of Creatinine-Based AKI Prediction in Intensive Care

This study introduces an EHR data passport framework to evaluate the cross-database transportability of creatinine-based AKI prediction models between MIMIC-IV and eICU, revealing that while discrimination remains stable, significant differences in data computability, laboratory coverage, and calibration shifts necessitate rigorous pre-deployment stress testing and algorithmic vigilance.

Xiaoxi Zhang, Shaonan Wang, Giselle Chan, Lixin Yin2026-07-01
📄 medicine

Healthcare Ethics Literacy in Pre-Conflict Sudan: A Multi- Disciplinary Institutional Baseline Study from a Tertiary Hospital (2013–2014)

This 2013–2014 study of Sudan's Soba University Hospital reveals a profound systemic failure in healthcare ethics literacy, where despite universal undergraduate ethics training, 66% of frontline clinical providers demonstrated inadequate knowledge of core ethical principles and codes, highlighting a critical knowledge-attitude paradox that serves as a vital pre-conflict baseline for future health system reconstruction.

Algasim Abdelfrag, Muna F. Shaheen2026-07-01
📄 medicine

Efficacy of resistance vs. aerobic training for sarcopenia in cirrhotic patients: a systematic review

This systematic review of seven randomized controlled trials concludes that supervised physical exercise, particularly resistance training, is a safe and effective intervention for improving functional capacity and muscle strength in patients with liver cirrhosis, although evidence regarding muscle mass gains remains limited by protocol heterogeneity.

Priscila Meireles Calil Fontana, Rafael dos Santos Souza, Manuella Franco Cerqueira da Silva, Anete da Costa Medeiros, Y (…)2026-07-01
📄 medicine

Bacterial Spectrum, Antibacterial Resistance and Microbial Dysbiosis Among Cervical Cancer Patients and Their Associated Risk Factors: A Cross-Sectional Study in the Oncology Clinic, National Hospital, Abuja, Nigeria.

This cross-sectional study conducted at a tertiary hospital in Abuja, Nigeria, reveals a high prevalence (84.9%) of diverse bacterial infections with significant antibiotic resistance patterns among cervical cancer patients, highlighting the critical need for routine microbiological surveillance to manage dysbiosis and optimize treatment outcomes.

Chiamaka Ukamaka Oka, Marie-Esther Uju Dibua, Chinedu Simeon Aruah, Oka Ugochukwu Ezeabia, Rita Ngozi Nweke, John Anthon (…)2026-07-01
📄 medicine

Functional outcomes after megaprosthesis for neglected proximal femur pathological fractures: a retrospective case series

This retrospective case series of 12 patients demonstrates that surgical reconstruction using a modular megaprosthesis significantly improves functional mobility and reduces pain in individuals with neglected proximal femur pathological fractures, offering valuable insights for a clinical scenario lacking standardized management protocols.

Joaquim Soares do Brito, Catarina Massano, Francisco Serra Alves, André Spranger, Paulo Almeida, José Portela2026-07-01