📄 medicine

Predicting tuberculosis treatment relapse among geriatric patient using machine learning algorithms in a high Tuberculosis-burden Ghanaian setting.

This study demonstrates that a Random Forest machine learning model outperforms SVM, DNN, and Logistic Regression algorithms in predicting tuberculosis treatment relapse among geriatric patients in Ghana with 99% accuracy, leading to recommendations for its pilot integration into local clinic workflows and improved data-sharing policies.

Michael Aidoo, Rose-Mary Owusuaa Mensah2026-07-01
📄 medicine

Uncemented bipolar hemiarthroplasty with trochanteric clip and cable stabilisation as primary treatment for unstable intertrochanteric fractures in elderly patients with major comorbidities

This study demonstrates that uncemented bipolar hemiarthroplasty with trochanteric clip and cable stabilisation is an effective primary treatment for unstable intertrochanteric fractures in elderly patients with significant comorbidities, enabling early mobilization and achieving an 84.78% success rate at six months.

Muhammad Imran Javed, Muhammad Saad Bin Arshad Arain, Barbara Pierre Louis, Hooria Imran, Athar Zuberi, Niaz Hussain Kee (…)2026-07-01
📄 medicine

Improving discharge planning from acute inpatient mental health care settings: a realist review

This realist review synthesizes evidence from 77 documents and stakeholder input to reveal that achieving person-centred, collaborative discharge planning in acute mental health care requires a system-wide approach to address how macro-level factors like underinvestment and risk-averse cultures reinforce meso-level practices that inhibit micro-level relational care.

Melanie Handley, Corinna Hackmann, Lisa Marie Grünwald, Emma Kaminskiy, Charlotte Wheeler, Hannah Zeilig, Athena Sideri (…)2026-07-01
📄 medicine

Epidemic Keratoconjunctivitis in Conflict-Affected Kassala, Sudan (2024–2025): A Qualitative Exploration of Community Experiences and Health System Response

This qualitative study conducted in conflict-affected Kassala, Sudan, reveals how epidemic keratoconjunctivitis is exacerbated by health system fragility, socioeconomic barriers, and reliance on informal remedies, underscoring the urgent need for decentralized, community-coordinated eye care interventions.

Ibrahim Ibrahim, Abubakar Jibo, Fatima Sharif, Shawgi Adugory, Ebtisam Duffuaa, Manal Azrag, Razan Awadelkareem, Abdelra (…)2026-07-01
📄 medicine

Estimated Burden of Childhood Wheeze and Asthma Attributable to Infant RSV Lower Respiratory Tract Infection in the United States

This study estimates that approximately 11.1% of childhood wheeze and asthma cases in the United States are attributable to infant RSV lower respiratory tract infections, suggesting that a national nirsevimab program could prevent nearly 10,000 such cases annually.

Ian M. Galbreath, David W. Hutton, Allison M. LaRocco, Steven M. Brunwasser, Brittney M. Snyder, Amanda J. Driscoll, Pin (…)2026-07-01
📄 medicine

Permeation improvement and prolonged skin deposition of silymarin through shatdhauta ghrita cream: Formulation, dermatokinetic and anti-aging studies

This study demonstrates that formulating silymarin in a traditional Shatdhauta ghrita cream significantly enhances its skin permeation and deposition, prolongs its stability, and effectively exerts anti-aging effects by reducing oxidative stress markers while boosting antioxidant enzymes and collagen levels.

Moreshwar Patil, Madhuri Deshmukh2026-07-01
📄 medicine

Evaluating the Quantitative Perception of Residents of Paynesville City on the Excessive Alcohol Consumption among Adolescents and Youth

This pilot study utilizing a quantitative cross-sectional design and the FOAP framework reveals that residents of Paynesville City perceive excessive alcohol consumption among adolescents and youth as a significant and increasing public health challenge driven primarily by peer pressure and lack of parental control, necessitating urgent stakeholder intervention.

Forkpah Pewee, Cyrus N. Cooper2026-07-01
📄 medicine

Perceptions, Adoption, and Safe Water Handling Practices among Households in Borama District, Somaliland: A Community-Based Cross-Sectional Study

This community-based cross-sectional study in Borama District, Somaliland, reveals that while households possess high awareness of waterborne diseases and household water treatment methods, there is a significant gap between recognizing the importance of water treatment and consistently practicing it, highlighting the need for targeted education and training to improve sustained adoption.

yasin Ali, vitalis Okoth, Mirrium Mutuku2026-07-01