📄 medicine

Guideline-based multi-criteria decision analysis nursing intervention and central venous catheter infection-related indicators in a neurosurgical intensive care unit: a retrospective before-and-after study

This retrospective before-and-after study suggests that a guideline-based multi-criteria decision analysis nursing intervention in a neurosurgical ICU is associated with significantly reduced blood-culture positivity and lower post-catheterization severity scores, though it did not significantly decrease clinical signs of suspected catheter-related infection, warranting further prospective validation.

Yan Qi, Hao Wang2026-07-01
📄 medicine

Effects of High-Intensity Interval Training at 100% vs. 120% of VIFT on Physical Performance in U-17 Male Soccer Players

In a study of U-17 male soccer players, a 6-week high-intensity interval training program prescribed at 120% of the 30–15 Intermittent Fitness Test velocity (VIFT) yielded superior improvements in aerobic capacity, maximal velocity, standing long jump, and agility compared to training at 100% VIFT, while both protocols enhanced overall physical performance.

Ali Ghashghaie, Mohammad Hemmatinafar, Alireza Niknam, Javad Nemati, Rodrigo Ramirez-Campillo2026-07-01
📄 medicine

Imaging Monoacylglycerol Lipase A First-in-Human Positron Emission Tomography Study with [18F]MAGL-2102

This first-in-human study evaluates the novel PET radiotracer [18F]MAGL-2102 for imaging monoacylglycerol lipase, revealing that despite favorable preclinical data, its low brain uptake in humans precludes its use as a reliable tool for in vivo brain imaging, though the findings provide valuable guidance for future radioligand development.

Bertina Jebanesan, Lucas Narciso, Nikta Zarif Yussefian, Emily Murrell, Kimberly L. Desmond, Sang Soo Cho, Jerry Warsh (…)2026-07-01
📄 medicine

Visualization neuroinflammation in the brain of patients with neuronal intranuclear inclusion disease by TSPO-PET

This study demonstrates that TSPO-PET imaging reveals significantly elevated neuroinflammation in patients with neuronal intranuclear inclusion disease (NIID), which is closely linked to white matter fiber damage and suggests the utility of this modality for monitoring disease progression.

Ruiqing Ren, Jing Wang, Shaoping Zhong, Yuzhe Li, Qingyu Lin, Kaiyuan Shen, Jingzhen Liang, Yuchen Gong, Dengfeng Cheng (…)2026-07-01
📄 medicine

Assessment of Iodine Status Among Pregnant Women in Sri Lanka Using Urinary Iodine Concentration.

Despite Sri Lanka's long-standing Universal Salt Iodisation program, a cross-sectional study of 337 first-trimester pregnant women reveals that iodine insufficiency remains prevalent with significant district-level disparities, while a notable minority also exhibit excessive intake, underscoring the need for enhanced monitoring and program evaluation.

Piyumi Weerawickrama, Darshana Hewage, Nethmi Dulanji Madarasinghe, Gayathri Amarakoon, Gayan Gunatilake, Samantha Ranas (…)2026-07-01
📄 medicine

Knowledge, Attitude and Practice About the Use of Mobile Health Application in Diagnosis of Anemia Among Women Population

This cross-sectional study of 400 women at a medical college reveals that while anemia awareness is consistent across socioeconomic groups, age and socioeconomic status significantly influence perceptions and acceptance of mobile health applications for diagnosis, highlighting the need for user-friendly tools to improve health outcomes.

Niveditha B, Naveena S S, Akila Ganesh, Nanda Balan I, Divyambika C. V2026-07-01
📄 medicine

Real-time structuring of the clinical information section for dopamine transporter SPECT reporting with a small language model pipeline: development and external validation

This study demonstrates that a locally deployable, fine-tuned small language model combined with rule-based postprocessing can effectively transform heterogeneous free-text clinical information into standardized, report-ready documentation for dopamine transporter SPECT with high accuracy and robust external validation, offering a cloud-independent solution for structured reporting.

Thomas Buddenkotte, Ivayla Apostolova, Susanne Klutmann, Rickmer Braren, Philipp T. Meyer, Ralph Buchert2026-07-01
📄 medicine

Serum Metabolites as Predictors of Symptom Burden in Patients with Breast Cancer Undergoing Chemotherapy

This study of ten breast cancer patients undergoing chemotherapy found that chemotherapy-induced alterations in serum metabolites related to cellular energy metabolism, potentially exacerbated by inadequate dietary intake, are associated with the occurrence and severity of gastrointestinal and neuropsychological symptoms.

Catherine Cherwin, Emily Roberts, Felipe Batalini, Sam M. Sorensen, Lida Mina, Kathryn J. Ruddy, Carolyn Harvey-Mead, Vi (…)2026-07-01
📄 medicine

Pretransplant predictors of one-year bone mineral density change after allogeneic stem cell transplantation in Colombian adults

This retrospective study of 48 Colombian adults undergoing allogeneic stem cell transplantation found that cumulative prednisolone exposure is the strongest pre-transplant predictor of significant bone mineral density loss at the femoral neck within one year, highlighting the need for early preventive strategies to mitigate glucocorticoid-induced bone deterioration.

Gustavo Adolfo Parra-Serrano, Paula Teresa Mantilla-Mantilla, María Luna-González, Adriana Reyes-Gonzalez, Karen Julieth (…)2026-07-01
📄 medicine

A randomized study comparing the iTind™ device versus UroLift™ (MT-08) - Interim report findings

This interim analysis of a randomized controlled trial (MT-08) involving 81 patients indicates that at three months, the iTind™ device demonstrates a favorable safety profile with no mid-term adverse events and symptomatic improvements comparable to the UroLift™ system, including preserved sexual function and rapid recovery.

Bilal Chughtai, Jennifer Polo, Naveen Kella, Neil Barber, Mark Rochester, Joel Abbott, Kalpesh Patel, Louis Krane, Sida (…)2026-07-01