📄 Category

medicine

6295 papers

📄 medicine

Multiscore Integration of GRACE, ACEF, and TIMI via Machine Learning for Risk Prediction of 6-Month Mortality in Acute Myocardial Infarction

This study demonstrates that a machine learning model integrating variables from GRACE, ACEF, and TIMI scores, optimized via a dual-stage feature selection process, achieves excellent discrimination for predicting 6-month mortality in acute myocardial infarction patients undergoing PCI, ultimately identifying a parsimonious three-variable model (Killip class, LVEF, and creatinine) that balances simplicity with robust clinical performance.

Wenqiang Li, Shengju Zan, Rui Guo, Yongling Zhao, Fuli Liang, Wei Hu2026-07-01
📄 medicine

COVID-19 Vaccination Coverage and its Associated Factors Among Healthcare Students at a Nigerian University

This study reveals that COVID-19 vaccination coverage among healthcare students at Usmanu Danfodiyo University, Sokoto, is critically low at 16.4%, with off-campus and hostel residence identified as the strongest independent predictors of uptake compared to living with family.

Ismail Tajudeen Hamza, Amir Yahaya, Ibrahim Anas Muhammad, Ibrahim Abubakar Sadeeq, Suleiman Abdullahi SarkinFulani, Abd (…)2026-07-01
📄 medicine

Impact of climate change and associated extreme weather events on primary care: A multi- perspective qualitative study in multimorbidity

This qualitative study in England reveals that while people with multimorbidity and their caregivers perceive extreme weather as less relevant locally, they recognize its disproportionate impact on health and care systems, calling for equity-focused, integrated adaptation strategies to build climate resilience in primary care.

Glenn Simpson, Lucy Smith, Riya Tiwari, Paul Little, Miriam Santer, Joanne Lloyd, Hajira Dambha-Miller2026-07-01
📄 medicine

Assessing Adherence to Prophylactic Antibiotic Guidelines in Cesarean Sections in Rwanda

A prospective observational study of 295 cesarean sections at two Rwandan hospitals revealed that while prophylactic antibiotic administration was nearly universal, strict adherence to WHO guidelines was achieved in only 17.6% of cases due to frequent deviations in antibiotic selection, timing, and unnecessary postoperative use, highlighting an urgent need for strengthened antibiotic stewardship to combat antimicrobial resistance.

Genereuse Irakoze Iradukunda, Betty Kabarungi, Birhanu Abera Ayana, Charles Okot Odongo2026-07-01
📄 medicine

Hypoxia-Induced HIF-1α Drives the Progression of Odontogenic Keratocysts via the Sonic Hedgehog Pathway and PLK1-Mediated Osteolytic Remodeling

This study demonstrates that hypoxia-driven HIF-1α promotes the progression of odontogenic keratocysts by activating the Sonic Hedgehog pathway to enhance fibroblast proliferation and invasion, while simultaneously stimulating PLK1-mediated osteolytic remodeling through osteoclast activation.

Qixian Gai, Jiabei Mu, Zixian Xu, Yantong Chen, Shan Wang, Zheyi Sun, Jiemei Zhai2026-07-01