📄 medicine

The use of male slings in the treatment of severe post prostatectomy urinary incontinence: a comparative study in patients with or without radiotherapy

This prospective study demonstrates that the Advance XP male sling is a viable treatment for severe post-prostatectomy urinary incontinence with high overall satisfaction rates, although prior radiotherapy is associated with lower social continence outcomes.

Bruno Rodrigues Lebani, Monaliza Marizete Baungratz, Andre Barcelos da Silva, Felipe Placco Araújo Glina, Hudson de Lima (…)2026-07-01
📄 medicine

Current Status of Scoliosis Screening Findings and Associations With Physical Activity and Health Behaviors Among Chinese Children and Adolescents: A Cross-Sectional Survey in Shanghai, Xinjiang, and Fujian

A cross-sectional survey of nearly 9,500 Chinese students across three regions reveals a 3.0% scoliosis screening positivity rate (ATR ≥ 7°), identifying female sex, higher grade level, lower BMI, family history, and specific health behaviors like sedentary lifestyle and insufficient sleep as key factors associated with abnormal findings.

Yuanyuan Cao, Mengjia You, Shaochun Shi, Yina Wu, Xu Liu, Mengjia Feng, Xinfeng Zheng, Weibing Wu, Jun Xia2026-07-01
📄 medicine

The first CDC42 variant (p.Arg68Gln) associated with Takenouchi-Kosaki syndrome in Asia: a case report and literature review

This case report describes the first Asian pediatric patient with the ultra-rare de novo CDC42 p.Arg68Gln variant causing Takenouchi-Kosaki syndrome, detailing the patient's clinical presentation and treatment while reviewing existing literature to address ethnic data gaps and improve future clinical recognition and management.

Xiaoxiao Lin, Yuanyuan Song, Jiacheng Xue, Hua Liu2026-07-01
📄 medicine

A Comparative Study of the Efficacy of Unilateral Dual-Channel Endoscopic Targeted Resection of the S1 Superior Articular Process Tip versus MIS-TLIF in the Treatment of High-Level L5-S1 Extremely Lateral Disc Prolapse

This retrospective study of 450 patients demonstrates that unilateral dual-channel endoscopic targeted resection of the S1 superior articular process tip offers comparable long-term clinical efficacy to MIS-TLIF for high-level L5-S1 extraforaminal disc herniation, while providing significant advantages in reduced trauma, faster recovery, and preservation of segmental mobility.

YANCHUN XIE, YI LIAN, ANWU XUAN, HONGWEN GU, JUNCHAO LI, HAILONG YU2026-07-01
📄 medicine

LLO Reactivation of pre-existing T cell memory by a LADS-TT vaccine induces potent anti-tumor immunity in cervical and colon carcinoma models

This study demonstrates that a novel LADS-TT-L vaccine, engineered from an attenuated *Listeria* strain to deliver a long tetanus toxoid fragment, reactivates pre-existing memory T cells to induce a potent Th1-mediated anti-tumor immune response that effectively suppresses cervical and colon carcinomas in murine models.

Yongshu Wu, Jing Sun, Laiyin Hu, Mengyuan Gao, Yifan Wang, Mianmian Chen, Jiali Xu, Yue Han, Simin Deng, Zheng Nie, Chao (…)2026-07-01
📄 medicine

Parental Bladder Health Knowledge, Beliefs, Practices and Barriers Related to Pediatric Lower Urinary Tract Symptoms in Hispanic Children

This qualitative study of Spanish-speaking Hispanic families reveals that while parents recognize the importance of hydration, they lack knowledge about regular bladder emptying and constipation management, facing significant barriers at individual, interpersonal, organizational, and community levels that necessitate coordinated, culturally tailored interventions to improve pediatric lower urinary tract symptom outcomes.

Juan C. Angulo-Lozano, Pranaya Venkatapuram, Rachelle Balili, Aditi Sharma, Cati Brown-Johnson, Kathleen M. Kan2026-07-01
📄 medicine

Adjunctive Thiamine Therapy in Children with Sepsis: A Randomized Clinical Trial Evaluating Organ Dysfunction and Clinical Outcomes

In a randomized clinical trial of 168 children with sepsis, adjunctive thiamine therapy was associated with a significantly shorter intensive care unit stay and favorable, though mostly non-significant, trends in mortality and organ dysfunction, with the most pronounced benefits observed in patients with moderate to severe baseline organ failure.

Fatemeh Aghamehdi, Amirhossein Nohi, Babak Fathi Roudsari, Yasaman Aminpour, Mahmoud Bakhtiari, Mahya Hayati, Amirhossei (…)2026-07-01
📄 medicine

Association between the triglyceride-glucose index and poor prognosis in patients undergoing endovascular therapy across glucose metabolic status groups

This multicenter retrospective study demonstrates that a higher triglyceride-glucose (TyG) index is independently associated with poor 90-day prognosis in acute ischemic stroke patients undergoing endovascular therapy, a relationship that remains significant across normal glucose regulation and diabetes groups despite the highest poor outcome rates occurring in diabetic patients.

wei deng, Zhengqiao Bao, Jun Han, Peiyang Zhou, Guangxian Nan, Yanli Sun2026-07-01
📄 medicine

Factors Associated with Cardiac Arrest and Postoperative Survival Following endovascular abdominal aortic aneurysm repair (EVAR)

This retrospective study of 3,756 EVAR patients identifies advanced age, coronary artery disease, chronic kidney disease, and high ASA class as independent predictors of the rare but highly lethal complication of in-hospital cardiac arrest, which significantly reduces survival rates.

Hidayet Demir, Mehmet Semih Belpinar, Mehmet Altuğ Tunçer, Mehrdad Sheikhvatan2026-07-01