📄 Category

medicine

6295 papers

📄 medicine

Epidemic Keratoconjunctivitis in Conflict-Affected Kassala, Sudan (2024–2025): A Qualitative Exploration of Community Experiences and Health System Response

This qualitative study conducted in conflict-affected Kassala, Sudan, reveals how Epidemic Keratoconjunctivitis (EKC) is exacerbated by health system fragility and displacement, leading to delayed care-seeking and social disruption, while highlighting the urgent need for decentralized services and community-trusted communication strategies to effectively manage the outbreak.

Ibrahim Ibrahim, Abubakar Jibo, Fatima Shrif, Shawgi Adugory, Ebtisam Duffuaa, Manal Azrag, Razan Awadelkareem, Abdelrah (…)2026-07-01
📄 medicine

Emergence of pfhrp2 and pfhrp3 Gene Deletions in Plasmodium falciparum and Diagnostic Challenges in Bangladesh

This study confirms that widespread *pfhrp2* and *pfhrp3* gene deletions in *Plasmodium falciparum* isolates from Bandarban, Bangladesh, are causing false-negative HRP2-based rapid diagnostic test results, thereby posing a significant threat to malaria elimination efforts and necessitating an urgent shift to alternative diagnostic strategies.

Mohammad Shafiul Alam, Anamul Hasan, Md Mushfiqur Rahman, Amit Kumer Neogi, Md Mosiqure Rahaman, Shyamol Kumer Das, Afri (…)2026-07-01
📄 medicine

Early Diagnosis of Ischemic Stroke on Non-Contrast CT Scans Using a Convolutional Neural  Network: A Case Study from Mulago National Referral Hospital, Uganda

This study demonstrates that a convolutional neural network integrated into a web-based platform can detect early ischemic stroke on non-contrast CT scans with accuracy comparable to a senior radiologist but in significantly less time, offering a promising solution to address specialist shortages in low-resource settings like Uganda.

Michael Kateregga, Irene Wanyana, Richard Keith Kwagala, James Senoga, Success Kamuhanda, Mike Nsubuga, Charles Batte, R (…)2026-07-01
📄 medicine

Clinical Reasoning in the AI era: A focused scoping review and narrative synthesis of conceptual, pedagogical, and assessment frameworks in health professions education

This scoping review and narrative synthesis reveals that while clinical reasoning in health professions education is supported by diverse conceptual and assessment frameworks, current AI-enabled studies predominantly rely on narrow, automatable proxies rather than a comprehensive, theory-informed construct model capable of capturing the full complexity of reasoning in the AI era.

Naomi Campbell-Woods2026-07-01
📄 medicine

Analysis of Clinical Features in Pulmonary Infection Based on Two Next-Generation Sequencing Tests of BronchoalveolarLavage Fluid

This retrospective study of 34 patients with severe or complicated pulmonary infections demonstrates that analyzing changes in pathogen distribution and normalized sequence counts between two consecutive bronchoalveolar lavage fluid next-generation sequencing tests can effectively guide precise antimicrobial therapy, distinguish between disease progression and treatment response, and help avoid unnecessary repeat testing.

Junzhang Qin, Xiandong Yin, Zhen Xiong2026-07-01
📄 medicine

Inhibition of SIK2 and SIK3 induces adaptive ER-phagy and creates a therapeutic vulnerability in ovarian cancer

This study reveals that inhibiting SIK2/3 kinases in ovarian cancer triggers adaptive ER-phagy via the PERK-ATF4-CCPG1 axis to promote survival, but combining SIK2/3 inhibition with autophagy blockade disrupts this protective mechanism, leading to lethal proteotoxic stress and tumor regression.

Zhen Lu, Rumeysa Ozyurt, Gamze Bildik, Weiqun Mao, Hailing Yang, Robert Bast2026-07-01
📄 medicine

Association of chronic diseases with depressive symptom trajectories in postmenopausal women: a population-based cohort study

This population-based cohort study of Chinese postmenopausal women reveals that a higher burden of chronic diseases, particularly stroke, kidney disease, and arthritis, significantly increases the risk of persistently severe depressive symptom trajectories over a decade, with sleep duration and cognitive function acting as key mediating factors.

Mengna Shou, Zheng Liu, Mengfei Ye, Junjiang Wu, Zimu Fu2026-07-01
📄 medicine

Home-based geriatric rehabilitation after shortened inpatient rehabilitation: Cost-effectiveness analysis of the “Better@Home” multicentre prospective cohort study with a matched historical control group

The "Better@Home" multicentre study demonstrates that home-based geriatric rehabilitation following shortened inpatient care is a cost-effective alternative to conventional inpatient rehabilitation, achieving comparable levels of patient independence in daily activities while reducing overall healthcare costs.

C.J. Gamble, W.G. Groen, M. Vaz, M.W.M. Waal, M.C. Pol, E.F. van Dam van Isselt, M. Hiligsmann, A. Gabrio, S.M.G Zwakhal (…)2026-07-01
📄 medicine

Outcomes Following Gastric Bypass Reversal for Refractory Complications: A UK Tertiary Centre Retrospective Case Series

This retrospective UK case series of eight patients undergoing gastric bypass reversal for refractory complications found that while the procedure successfully improved nutritional status and BMI, it provided inconsistent relief from persistent symptoms such as pain, reflux, and vomiting, highlighting the need for better selection criteria and timing for definitive intervention.

Maria Victoria Rodriguez Noci, Georgios Ntampakis, Annika Stewart, Myutan Kulendran, Georgios Vasilikostas, Marcus Reddy (…)2026-07-01