📄 medicine

Comparative Diagnostic Accuracy of GeneXpert MTB/RIF and TB-LAMP for Tuberculosis Detection Among Presumptive Tuberculosis Cases in Bayelsa State, Nigeria

This study in Bayelsa State, Nigeria, found that while TB-LAMP offers higher sensitivity for initial screening, GeneXpert MTB/RIF demonstrates superior concordance with culture and the critical ability to detect rifampicin resistance, supporting a sequential diagnostic algorithm where TB-LAMP is used for screening followed by GeneXpert for confirmation.

Patrick UMUWE, Kennedy T. Wariso, Jude ILOZUMBA, Mabel Emudiaga-Ohwerhi, Stephen Uchechukwu OKOLI, Chizaram Precious DAN (…)2026-07-01
📄 medicine

Biomechanical Behavior of MOD Composite Restorations Reinforced with InFibra versus Ribbond Polyethylene Fibers: An In Vitro Evaluation

This in vitro study demonstrates that while reinforcing MOD composite restorations with either InFibra or Ribbond polyethylene fibers did not significantly increase fracture resistance compared to a control group, both fiber systems significantly promoted more favorable and repairable failure patterns.

Esraa Esmeail H. Elhaddad Elhaddad, Dina Fayez S. Diab Diab2026-07-01
📄 medicine

Mid-treatment radiologic response as an early predictor of pathologic response in TNBC in the era of pembrolizumab

In this retrospective study of 517 triple-negative breast cancer patients, mid-treatment radiologic complete response emerged as a stronger predictor of pathologic complete response than post-treatment imaging, with pembrolizumab demonstrating the highest likelihood of inducing early radiologic response.

Soong June Bae, Na Lae Eun, Jee Hung Kim, Yoonwon Kook, Ji Hyun Youk, Jeong-Ah Kim, Eun Ju Son, Joon Jeong, Yoon Jin Cha (…)2026-07-01
📄 medicine

Biogenic MSC‑derived exosomes as innovative nanobiocarriers enhancing doxorubicin‑induced apoptosis in leukemia cells

This study demonstrates that bone marrow mesenchymal stem cell-derived exosomes serve as efficient nanobiocarriers for doxorubicin, significantly enhancing its antileukemic potency and inducing apoptosis in K562 cells while minimizing necrotic damage compared to free drug administration.

Hamed Tabasi, Hamid Babavalian, Fatameh Shakeri, Mehrdad Moosazadeh Moghaddam2026-07-01
📄 medicine

ST-elevation myocardial infarction with left ventricular non-compaction and dual left anterior descending artery anatomy: a case report

This case report describes the first documented instance of ST-elevation myocardial infarction occurring in a patient with both left ventricular non-compaction and a rare dual left anterior descending artery anatomy, where three-dimensional coronary CTA was crucial for diagnosing the complex anomaly and guiding successful stent implantation.

Yuan Wang, Xing-Yu Huo, Ji-Bing Du2026-07-01
📄 medicine

Trends in Occupational Injuries 2017 to 2023: A Secondary Analysis of the National Trauma Data Bank

This retrospective analysis of the National Trauma Data Bank from 2017 to 2023 reveals significant demographic shifts in U.S. occupational injuries, characterized by increasing proportions among younger and older workers, females, Hispanic individuals, and those without private insurance, while identifying specific clinical and socioeconomic factors associated with longer hospital stays and higher mortality rates.

Julian Chen, Alexnys Fernandez-Pacheco, Tanner Besse, Leigh Burgess, Rachel Orlowski, Tracy Johns, Shayne Gue2026-07-01
📄 medicine

Anti-GM2 IgG-positive autoimmune brainstem encephalitis presenting as a stroke mimic: a case report and literature review

This case report describes a 28-year-old male with anti-GM2 IgG-positive autoimmune brainstem encephalitis who presented with stroke-like symptoms but negative imaging, ultimately achieving significant improvement with corticosteroid therapy, thereby highlighting the importance of antibody testing in young patients with incongruent clinical and radiological findings.

TIAN YANG SHENG, Hui Zhang2026-07-01
📄 medicine

Comparison of Short-term Clinical Prognosis and Independent Risk Factors for Complications After Airway Stent Implantation for Benign and Malignant Airway Diseases

This study demonstrates that while airway stenting effectively alleviates dyspnea in both benign and malignant airway diseases, patients with malignant lesions face significantly higher complication rates, and undergoing stent implantation two or more times is an independent risk factor for postoperative complications.

xia yang, meihua zhang, xiaoping xu, shuang zhao, penghao huang, jian sun2026-07-01