📄 medicine

Lifestyle Factors and Symptom Burden in Endometriosis: An Exploratory Mixed-Methods Analysis of Nutrition, Physical Activity, and Psychosocial Well-being

This exploratory mixed-methods study suggests that while physical activity and psychosocial well-being show modest associations with endometriosis symptom burden, the findings support the need for individualized lifestyle interventions as adjuncts to conventional treatment, pending validation through rigorous longitudinal research.

Laura Wulfhorst, Andrea Henze, Dorothea Portius2026-06-30
📄 medicine

Digital Twin–Enabled Robotic Surgery: A Bibliometric and Knowledge-Mapping Analysis from Patient-Specific Simulation to Autonomy and Clinical Translation

This bibliometric study analyzes 508 publications from 2010 to 2026 to map the rapidly evolving landscape of digital twin-enabled robotic surgery, revealing a field in early rapid growth that is shifting from simulation toward AI-driven autonomy and clinical translation while highlighting the need for standardized definitions and multicenter validation.

Defu Yang, Feng Shang, Jing Liu, Xinying Ma, Jianjing Wang, Ying Li, Ying Xu, Ying Yan, Dongyang Lv2026-06-30
📄 medicine

Reconstructed physical network for disease spread using age-based contact data: Simulations of case studies across Chinese regions

This study reconstructs age-based disease transmission networks for Chinese regions using real contact data and compares them with random and Barabási-Albert models to analyze outbreak thresholds via a two-layer SEIR model, revealing that network structure correlates with economic development levels and that younger populations face higher infection risks due to distinct contact patterns.

First Hong yu Cai, Second Guanghui Yan, Third Huayan Pei2026-06-30
📄 medicine

Safety and Complications of Upper Pole Puncture in Supine Percutaneous Nephrolithotomy

This multicenter retrospective study demonstrates that upper pole punctures in supine percutaneous nephrolithotomy are as safe as middle and lower calyx accesses, with observed lower stone-free rates primarily attributed to higher stone complexity rather than the puncture site itself.

Juliana Villanueva-Congote, Yi W Li, Michal Segall, Mehmet Gokce, Silvia Proietti, Guido Giusti, Braulio Manzo, Alan Yag (…)2026-06-30
📄 medicine

Total-Body PET of Two Approved PARP Inhibitors: [18F]Olaparib and [11C]Niraparib

This study utilizes total-body PET to compare the biodistribution of two radiolabeled PARP inhibitors, [11C]Niraparib and [18F]Olaparib, in rhesus macaques, revealing that [11C]Niraparib exhibits significantly higher uptake in the central nervous system while [18F]Olaparib shows greater accumulation in the spleen.

Konstantinos Plakas, Bhasker Radaram, Banafshe Samani, Chia-Ju Hsieh, Anthony Young, Alexander Schmitz, Catherine Hou, Z (…)2026-06-30
📄 medicine

Molecular Identification of Hypoderma sinense Cutaneous Myiasis in a Child from a Cattle-Raising Pastoral Region of China: A Case Report

This case report details the molecularly confirmed diagnosis of rare *Hypoderma sinense* cutaneous myiasis in a Chinese child from a pastoral region, demonstrating how ultrasonography, minimally invasive larval extraction, and whole-genome sequencing can effectively identify and manage this zoonotic infestation that mimics common skin infections.

Qiuqin Ji, Shuyao He, Sha Lai, Siqi Long, Xinyi Jing, Yao Lu2026-06-30
📄 medicine

An update to the critical vaccination threshold for measles herd immunity

This paper presents a mathematical model incorporating waning vaccine-induced immunity to derive updated measles herd immunity thresholds, demonstrating that even minimal immunity loss can fundamentally alter transmission dynamics and render traditional critical vaccination targets insufficient for achieving herd immunity in highly vaccinated populations.

Mahmuda Ruma, Elena Aruffo, Alexandra Teslya, Jane Heffernan2026-06-30
📄 medicine

Effect of Root Canal Curvature on Apical Pressure Generated by Multisonic and Syringe-Needle Irrigation: An In Vitro Study

This in vitro study demonstrates that the GentleWave G4 ProControl multisonic system consistently generates negative apical pressures across all canal curvatures, whereas syringe-needle irrigation produces significantly higher positive pressures that increase with curvature, highlighting the superior safety profile of multisonic irrigation against apical extrusion.

Mustafa Gündoğar, Taha Özyürek, Hande Özyürek2026-06-30
📄 medicine

Forecasting Influenza Incidence and Analyzing Interactive Effects of Environmental Factors across Different Age Groups in Beijing

This study analyzes influenza epidemiology in Beijing from 2005 to 2020, demonstrating that the Holt-Winters model outperforms other time series methods for single-factor forecasting while a Bi-LSTM model effectively integrates meteorological and air pollutant data to reveal age-specific environmental triggers and interaction effects for targeted prevention strategies.

Guolong Qu, Weiming Hou2026-06-30
📄 medicine

Combined Corneal Cryotherapy and Conjunctival Flap for Adjuvant Treatment of Medically Resistant Acanthamoeba Keratitis: A Case Series

This retrospective case series demonstrates that combining corneal cryotherapy with conjunctival flap placement serves as an effective salvage treatment for medically refractory Acanthamoeba keratitis, successfully controlling infection and preserving vision in all three patients without the need for enucleation.

Lena Chen, Evan Frigoletto, Lingo Lai, Thomas F. Mauger2026-06-30