6295 papers
This study demonstrates that oral vitamin C administration significantly attenuates trichloroacetic acid-induced cardiac injury, inflammation, and myocardial fibrosis in rats by improving biochemical markers and preserving cardiac tissue structure.
In an international multicenter cohort of 277 patients, high-grade biopsy histology was identified as the strongest independent predictor of recurrence following endoscopic management of upper tract urothelial carcinoma, occurring in 34.7% of cases and guiding the need for intensified surveillance and potential delayed radical nephroureterectomy.
This prospective paired-eye study reveals that short-term aqueous humor cytokine and metabolomic changes in the second eye following first-eye cataract surgery are etiology-dependent, with significant transient molecular fluctuations observed in diabetic and high myopia-associated cataracts but not in age-related cataracts.
This case report describes a rare instance of whole maternal isodisomy 6 with confined placental mosaicism causing intrauterine growth restriction but resulting in a favorable postnatal outcome at 27 months, suggesting that excluding pathogenic variants via CMA and WES can predict a positive prognosis in similar cases.
This prospective cohort study of 1,311 acute stroke patients in Guinea reveals that delayed hospital presentation, severe neurological impairment, and aspiration pneumonia are key factors driving a high in-hospital mortality rate of 19.6%, with aspiration pneumonia identified as the strongest modifiable predictor of death.
This randomized controlled trial demonstrates that while both platelet-rich fibrin and chorion membranes combined with hydroxyapatite grafts effectively promote periapical healing after endodontic surgery, the chorion membrane group exhibited a superior vascular response on colour Doppler imaging despite no statistically significant difference in hard-tissue healing outcomes.
This qualitative study reveals that while surgeon parents find parenthood meaningful, they face significant emotional and professional challenges due to demanding work schedules and institutional gaps in support, highlighting an urgent need for structural interventions like flexible scheduling and improved childcare resources.
This retrospective study of 344 patients undergoing labor induction with oral misoprostol found that higher Body Mass Index (BMI) is significantly associated with a longer time to delivery, a greater number of misoprostol doses required, and an increased rate of cesarean delivery.
This systematic review evaluates the validity of current assessment tools for robotic surgery, revealing that while existing methods like GEARS and OSATS have strong internal structure evidence, there is a significant gap in validated tools covering most ACS/APDS skill modules and a lack of evidence regarding the consequences of assessment.
This study reveals that pediatric surgery orientation materials for general surgery residents convey a hidden curriculum containing both positive messages about compassion and communication and negative assumptions that deprioritize education and view residents as liabilities, highlighting the need to align these written materials with formal educational goals.