6295 papers
The PAMS program, a multimodal addiction prevention initiative in French sports settings utilizing social media, professional training, and athlete testimonies, demonstrated successful implementation and high engagement among both digital audiences and sports professionals.
This study reveals that immune and gastrointestinal symptoms in ME/CFS exhibit distinct latent structures that differ by sex, with women showing separable but related immune and gut clusters that are differentially modulated by menopausal status, whereas men display a single integrated immune–gastrointestinal factor.
This 9-year prospective nationwide cohort study of over 10,000 Chinese adults identified fifteen independent risk factors for cardiovascular disease, including dyslipidemia, hypertension, and specific chronic conditions, while demonstrating that a hierarchical analytical approach reveals significant variations in risk by age and sex to inform personalized prevention strategies.
This retrospective cohort study of 251 patients with upper gastrointestinal bleeding identifies advanced age (≥80 years) and severe anemia (hemoglobin <60 g/L) as independent predictors of endoscopic hemostasis failure and mortality, respectively, while suggesting a potential mortality benefit for combined hemostatic therapy in non-variceal cases.
This study identifies the Comprehensive Smoking Index (CSI) as the optimal indicator for predicting mortality risk in high-risk cardiovascular disease populations and demonstrates that a Cox model based on CSI achieves robust predictive performance comparable to complex machine learning algorithms.
This study demonstrates that while diabetic retinopathy is primarily associated with proteinuria in patients with type 2 diabetes, the presence of concomitant diabetic macular edema is a stronger indicator linked to all forms of chronic kidney disease, including reduced eGFR, suggesting fundus findings can aid in non-invasive renal risk stratification.
This retrospective cohort study of 910 Chinese adults reveals that while high fat mass is an independent risk factor for prediabetes, the combined low muscle mass and high fat mass phenotype offers limited incremental predictive value beyond traditional indicators like waist circumference and GGT, except potentially for identifying high-risk males.
This study developed and validated a nomogram incorporating multidimensional features like LODDS and SII to predict early recurrence in high-risk biliary tract cancer, while real-world evidence demonstrated that adjuvant chemoimmunotherapy significantly reduces the risk of early postoperative recurrence compared to surgery alone or chemotherapy.
This study demonstrates that TERC-FISH is a reliable biomarker for confirming cervical intraepithelial neoplasia and resolving discrepancies between histological and cytological diagnoses, as TERC amplification correlates strongly with lesion severity and high-risk HPV infection.
This retrospective study of 118 hospitalized Alzheimer's disease patients utilized K-means clustering to identify three distinct functional–behavioral subtypes characterized by varying levels of impairment and symptom severity, thereby supporting the development of multidimensional risk stratification and individualized care planning.