6308 papers
This prospective study demonstrates that preoperative anterior segment optical coherence tomography can identify zonular weakness risk in cataract surgery patients, where a reduced lens front radius (≤ 8.58 mm) predicts mild-to-severe weakness and significant lens decentration (≥ 0.25 mm) specifically indicates severe weakness.
This study demonstrates that an ensemble machine learning model utilizing readily available inflammatory markers, such as complete blood count parameters and C-reactive protein, can accurately predict 30-day mortality in pediatric patients following cardiopulmonary bypass, with SHAP analysis revealing that low platelet counts and paradoxically low C-reactive protein levels are key risk indicators.
This case report describes a 19-year-old female with Rapunzel syndrome who developed gangrenous small bowel obstruction due to a trichobezoar, highlighting the critical need for early surgical intervention and long-term psychiatric management in young females with trichophagia presenting with intestinal obstruction.
This study utilizes a 3D bioprinted nasopharyngeal carcinoma spheroid model to demonstrate that constitutive IGF-1R/PI3K/AKT signaling drives intrinsic cetuximab resistance and that targeting this pathway with OSI-906 effectively reverses resistance, offering a promising therapeutic strategy for the disease.
This in vitro study demonstrates that dynamic navigation mediated photogrammetry (DNMP) achieves clinically acceptable trueness for full-arch implant digital impressions, with accuracy levels that remain consistent regardless of implant positional relationships.
In a propensity-weighted analysis of 15,660 hospitalized emergency department patients with suspected infection, early ultrasound was associated with significantly faster antibiotic administration but showed no significant impact on hospital mortality, ICU admission, or vasopressor use, suggesting its primary role is as a diagnostic process accelerator.
This systematic review and meta-analysis of 97 studies demonstrates that poor glycemic control in patients with diabetes and pulmonary tuberculosis is significantly associated with worse treatment outcomes, including lower response and sputum conversion rates, reduced lesion resolution, higher recurrence, and impaired inflammatory and immune markers, exhibiting a clear dose-response relationship.
This convergent mixed-methods study evaluates the implementation of measurement-based care across three child and adolescent mental health services within an academic-health system partnership, finding high acceptability and fidelity in intensive settings while identifying leadership support, innovation culture, and partnership dynamics as key determinants of success.
The Veterans Precision Oncology Data Commons (VPODC) introduces a secure, app-centric framework that enables researchers to rapidly train and validate privacy-preserving patient-level prediction models on large-scale VA clinical and genomic data without direct data access, demonstrating high predictive accuracy and cost-efficiency.
This retrospective study of 460 hospitalized adults with Influenza A(H1N1) in Xi'an identifies chronic respiratory diseases and hypoproteinemia as independent risk factors for bacterial pneumonia, a complication associated with heightened inflammatory markers, greater clinical severity, and longer hospital stays.