📄 medicine

Geographic accessibility to childbirth care in Lubumbashi city, Democratic Republic of Congo using a census-based database of health facilities and context-specific travel speeds

This study utilizes a comprehensive census-based database and context-specific travel speeds to reveal that while primary-level childbirth care is geographically accessible to most women in Lubumbashi, DRC, hospital-level care remains effectively inaccessible for the poorest populations and those in peripheral areas due to significant travel time disparities driven by unplanned urban growth and low facility density.

Abdulu Mahuridi, Ann M Njogu, Angèle Musau Nkola, Aline Semaan, Lorenzo Libertini, Ilunga Mpoyi Tabitha, Debaïf Mutombo (…)2026-06-29
📄 medicine

The Impact of Implementing Free School Lunch Policies on the Effectiveness of Meeting Children's Nutritional Adequacy in Sweden: A Scoping Review

This scoping review evaluates Sweden's universal free school lunch policy, finding that while it significantly improves children's intake of vegetables, fish, and specific micronutrients and helps reduce social dietary inequalities, it still falls short of national standards for several key nutrients and requires enhanced monitoring and sustainable menu planning to fully realize its public health potential.

Risqina Sari, Moses Glorino Rumambo Pandin2026-06-29
📄 medicine

From Beliefs to Behaviour: A Scoping Review of Health Communication Theories and Strategies for NCD Prevention on Social Media

This scoping review of nine studies (2012–2023) reveals that while social media programs for non-communicable disease prevention frequently employ effective strategies like tailored education and peer support, they often rely heavily on the Health Belief Model with superficial theoretical application, highlighting a need for broader theoretical diversity, adoption of newer platforms, and increased research in low- and middle-income countries.

Thilak Wanasinghe2026-06-29
📄 medicine

Bioanalytical Method Validation and Pharmacokinetic Application of an RP-HPLC-PDA Method for the Simultaneous Estimation of Dapagliflozin and Sitagliptin in Rat Plasma

This study developed and validated a simple, accurate, and precise RP-HPLC-PDA method for the simultaneous quantification of dapagliflozin and sitagliptin in rat plasma according to ICH guidelines, successfully applying it to determine their in vivo pharmacokinetic parameters.

Ponnilavarasan Ilangovan, Tamilselvi, Thiruvengadarajan2026-06-29
📄 medicine

Unraveling the Landscape of HIV/AIDS Knowledge, Stigma, and Prevention Behavior in Indonesia: A Systematic Mini Literature Review

This systematic mini literature review of ten studies reveals that despite extensive government efforts, HIV/AIDS knowledge in Indonesia remains inadequate and heavily influenced by sociodemographic factors, while persistent stigma and misinformation necessitate multi-level, culturally sensitive interventions that integrate health literacy, social support, and diverse educational platforms to improve prevention behaviors.

Nadia Suci Dwi Nur Hidayah, Moses Glorino Rumambo Pandin2026-06-29
📄 medicine

Commercial AI for Opportunistic Detection of Vertebral Compression Fractures on Routine CT: A Systematic Review of Diagnostic Performance and Clinical Yield

This systematic review of eight retrospective studies involving over 6,000 patients demonstrates that commercially available AI tools for opportunistic vertebral compression fracture detection on routine CT exhibit high specificity and negative predictive value, effectively identifying fractures missed in standard radiology reports, though their clinical adoption requires prospective outcome studies to validate patient benefit.

Amir Srour, Mahmud Omar, Yiftach Barash, Diana Litmanovich, Mayse Srour-Asmar, Eyal Klang, Alon Gorenshtein2026-06-29
📄 medicine

Attention-Deficit/Hyperactivity Disorder Knowledge and Recognition Among Frontline Professionals in Ethiopia: A Study of Health Professionals and Primary School Teachers

A comparative study conducted in southern Ethiopia reveals that health professionals and primary school teachers possess inadequate knowledge regarding ADHD, with recognition levels significantly correlated to prior experience in diagnosing or treating the condition, highlighting an urgent need for targeted training initiatives.

Mahidere Ali, Frank Adusei-Mensah, Rediet Dayemo, Tomi-Pekka Tuomainen, Mihiretu Tesfamariam Goshu2026-06-29
📄 medicine

Concordance Validation of GenomeGuard, a Lightweight VCF-Based Pharmacogenomic Interpretation Engine, Against PharmCAT Using 1000 Genomes South Asian Whole-Genome Sequencing Data

This study demonstrates that GenomeGuard, a lightweight Python-based pharmacogenomic interpretation engine, achieves near-perfect concordance with the established PharmCAT tool in South Asian whole-genome sequencing data while offering a dramatic 1391-fold improvement in execution speed, making it highly suitable for real-time clinical deployment in resource-constrained settings.

Aditya Yadav2026-06-29
📄 medicine

Efficacy of neuromuscular electrical stimulation as a therapy for sarcopenia in people on haemodialysis: study protocol for the STIM-HD randomised controlled trial

The STIM-HD study is a multi-centre, assessor-blinded randomised controlled trial designed to evaluate the clinical efficacy, cost-effectiveness, and biological mechanisms of neuromuscular electrical stimulation (NMES) as a treatment for sarcopenia in adults receiving haemodialysis.

Emma L Watson, Niamh Quann, Faizan Awan, Shaun R Barber, Nicola Cooper, Indranil Dasgupta, Jonathan P Folland, Laura J G (…)2026-06-29