medicine papers | Gist.Science

Effects of mechanical thrombectomy combined with anticoagulation vs anticoagulation monotherapy for acute intermediate-high risk pulmonary embolism: study protocol for a randomized controlled trial(CAPE study

The CAPE study is a multinational randomized controlled trial protocol designed to evaluate the efficacy and safety of mechanical thrombectomy combined with anticoagulation versus anticoagulation monotherapy for treating acute intermediate-high risk pulmonary embolism, with a specific focus on providing evidence for Asian populations.

Qiang Huang, Lin Feng, Lin Liu, Yi-Shan Li, Wei Guo, Fa-Jiu Li, Li Li, Yu-Nong Ren, Chuan-Guo Zhou, Shuai Zhang, Meng Zh (…)2026-06-29

📄 medicine

Quality of Life and Its Determinants Among Palliative Care Cancer Patients at Kisii Teaching and Referral Hospital, Kenya: A Cross-Sectional Study

This cross-sectional study of 120 palliative care cancer patients at Kisii Teaching and Referral Hospital in Kenya reveals that while physical symptoms are relatively well-managed, psychological wellbeing is the most compromised aspect of quality of life, which is significantly influenced by a combination of socio-demographic and clinical factors.

Ondimu Orindi, Enock Ngetich, Maximillah Muro2026-06-29

📄 medicine

Endoscopic Endonasal Approach in the Diagnosis and Treatment of Clival Metastatic Tumors

This retrospective study of 34 patients demonstrates that the endoscopic endonasal approach is a safe and effective first-line surgical option for diagnosing and treating clival metastatic tumors, offering low complication rates and facilitating both tissue confirmation and symptom relief.

Jacek Kunicki, Barbara Buchalska, Wiesława Grajkowska2026-06-29

📄 medicine

Effects and risk factors of heatwaves and air pollution on emergency health equity in South Western Sydney, Australia

This study utilizes granular emergency department data in South Western Sydney to demonstrate that culturally and linguistically diverse communities and individuals of low socioeconomic status suffer disproportionately from the health impacts of heatwaves and air pollution, underscoring the urgent need for targeted public health strategies to address these climate-related inequities.

Meg Newton, Jonathan Cohen, Prof. Paul M Middleton2026-06-29

📄 medicine

Characterization of orthogeriatric care models and association with mortality and health-economic outcomes in patients with hip fractures: a retrospective cohort study from Germany

This retrospective cohort study of German orthogeriatric centers reveals that while the extent of geriatrician involvement significantly influences mortality and rehabilitation delivery patterns, the overall direct inpatient medical costs remain similar across different care models.

Theresa Unseld, Kilian Rapp, Hans-Helmut König, Thomas Friess, Dietrich Rothenbacher, Gisela Büchele, Claudia Konnopka2026-06-29

📄 medicine

Cross-sectional assessment of common mental disorders among people with HIV/AIDS attending Ndera Neuropsychiatric Teaching Hospital, Rwanda, 2025

This 2025 cross-sectional study of 140 people living with HIV/AIDS at Ndera Neuropsychiatric Teaching Hospital in Rwanda reveals a high prevalence of psychiatric disorders, particularly schizophrenia spectrum disorders, and underscores the critical role of integrated mental health and HIV care in achieving viral suppression and improving quality of life.

Emmanuel Habiyaremye, Charles Nkubili, Jean Petit Habonimana, Pascal Uwamungu, Antoine Mutiganda, Emmanuel Ntakiyisumba (…)2026-06-29

📄 medicine

Peri-operative Safety in West Africa: Aligning Orthopaedic Residency Training With System-level Gaps Identified From DHS/SPA Data (2015–2025)

This study analyzes Demographic and Health Survey and Service Provision Assessment data from 2015–2025 to reveal critical peri-operative safety deficits across West Africa, arguing that orthopaedic residency training must evolve to address these system-level gaps through enhanced focus on infection control, damage-control orthopaedics, and resource-limited practice.

E. A. Owolabi¹, S. O. Osikoya¹, M. Ononye¹, F. I. Ogedegbe¹, J. O. Sotunsa¹2026-06-29

📄 medicine

Body Mass Index and Attention-Deficit/Hyperactivity Disorder in U.S. youth: a reverse J-shaped association

This study of U.S. youth reveals a non-linear, reverse J-shaped association between BMI and ADHD characterized by a protective threshold at 21.03 kg/m², where lower BMI is linked to higher ADHD risk, with red cell distribution width identified as a significant biological mediator of this relationship.

Jinjiang Shi, Xiu Che, Daidi Ling, Hongxin Li2026-06-29

📄 medicine

Impact of Short Videos on Agomelatine and Pregabalin Efficacy for Illness Anxiety Disorder: A Randomized Controlled Trial

This randomized controlled trial demonstrates that while agomelatine and pregabalin effectively treat Illness Anxiety Disorder, supplementing medication with leisure-oriented short videos yields superior and more sustained reductions in anxiety and health-related worry compared to health-related videos by promoting cognitive distraction over rumination.

Yanlin Liao, Wenhui Wang, Yuan Fang, Wenjun Zhang, Suqi Song, Kai Zhang2026-06-29

📄 medicine

Surveillance of Small Side-Branch Intraductal Papillary Mucinous Neoplasms: Is Long-Term Follow-Up Necessary?

This multicenter retrospective study suggests that small side-branch intraductal papillary mucinous neoplasms (SB-IPMNs), particularly those measuring ≤ 5 mm, exhibit a very low risk of malignant transformation comparable to larger lesions, indicating that current long-term surveillance protocols for these tiny cysts may be unnecessary and warrant re-evaluation to reduce imaging burden.

Aaiz Hussain, Alexander Pietroski, Ahmed Ahmed, Lavi Singh, Aazif Hussain, Arian Pakray, Emily Jagenburg, Myra Esmail, M (…)2026-06-29

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