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medicine

6308 papers

📄 medicine

Function-Preserving Gastrectomy with Sentinel Node Navigation versus Standard Gastrectomy for Early Gastric Cancer: A Systematic Review and Meta-analysis

This systematic review and meta-analysis of 1,193 patients across six studies concludes that while function-preserving gastrectomy with sentinel node navigation offers comparable 5-year overall survival to standard gastrectomy for early gastric cancer, it does not demonstrate a significant improvement in postoperative quality of life, highlighting the need for further randomized trials to validate surgical de-escalation strategies.

Lorenna Lim Andrade, Judith Mura, Pedro Fernandes Kalume, Eduardo Morales, Vinicius Vicuña2026-06-29✓ Author reviewed ⓘ
📄 medicine

Psychometric Properties of the Turkish Version of the Fear of Falling Scale for Older Adults: A Validity and Reliability Study

This study validates the Turkish version of the Fear of Falling Scale for Older Adults (FFSO-T) as a reliable and psychometrically sound instrument with a four-factor structure, demonstrating strong content, construct, and test-retest reliability for use in clinical and research settings with the elderly population.

Bedriye Cansu Koyunoğlu, Ercan Bakır, Gülcan Bahçecioğlu Turan2026-06-29
📄 medicine

Patient Characteristics, Motivations, and Satisfaction in an AI-Assisted Rapid-Access Pathway for the Evaluation of Skin Lesions: A Cross-Sectional Survey Study

This cross-sectional survey of 254 patients in Paris demonstrates that an AI-assisted rapid-access pathway for skin lesion evaluation, which integrates primary care dermoscopy and immediate surgical management, is highly satisfactory to patients and fosters positive attitudes toward AI, particularly among those with higher educational levels.

Laurène Masson, Raffaele Aguglia, Moshé Assouline, Theodoros Chrelias, Georgia Kanellopoulou, Haizam Oubari, Curtis L. C (…)2026-06-29
📄 medicine

Refractory Radiculopathy Without a Surgical Target: Ketamine Analgesia and Psychiatric Risk in Multilevel Degenerative Spine Disease

This case report illustrates the management challenges of refractory radiculopathy in a patient with psychiatric comorbidities and clinical-radiographic discordance, highlighting ketamine's analgesic potential while underscoring the critical need for early psychiatric support when surgical and procedural options are exhausted.

Zaid Mateen, Kevin Pena, Younis Sutari, Abed Rahman2026-06-29
📄 medicine

Survival and Determinants of Mortality among Adult Intensive Care Unit Patients in Ethiopia: A Multicenter Retrospective Cohort Study

This multicenter retrospective cohort study in Ethiopia reveals a 36.9% mortality rate among critically ill adult ICU patients with a median time to death of 15 days, identifying sepsis, chronic lung disease, hypotension, hyponatremia, vasopressor requirement, acute kidney injury, and tracheostomy as significant independent predictors of mortality.

Tola Getachew Bekele, Adebabay Wondimagegn Molla, Awol Seid Assen, Getu Girma Bekele, Legesse Fekede Abza2026-06-29
📄 medicine

Baseline depressive symptoms, major somatic disease, and frailty trajectories in older adults: a tri-cohort longitudinal study of CHARLS, ELSA, and HRS

This tri-cohort longitudinal study of older adults in China, England, and the US reveals that major somatic disease and its co-occurrence with depressive symptoms are consistently associated with higher baseline frailty and accelerated frailty accumulation over time, with the comorbid group exhibiting the least favorable trajectories across all national cohorts.

Bin Sun, Zihao Zheng, Jia Shi, Ziyi Zhang, Jiaxin Li, Hongchao Zhang, Shunkai Cai, Zhicheng Huang, Weihang Wu, Lizhi Lv2026-06-29
📄 medicine

Association Between the Triglyceride–Glucose Index and Short-Term Mortality in Critically Ill Patients: A Retrospective Cohort Study Using the MIMIC-IV Database

This retrospective cohort study of 6,342 critically ill patients using the MIMIC-IV database reveals that while an elevated Triglyceride–Glucose (TyG) index is significantly associated with increased 28-day mortality, its independent prognostic value is modest and attenuated when adjusted for organ dysfunction scores like SOFA, suggesting it may serve best as a complementary metabolic biomarker rather than a standalone predictor.

Xiaoqing Gan, Jianying Dai, Chao Ding, Qingjiang Lyu2026-06-29
📄 medicine

Assessing the diagnostic accuracy of the SD-Ov16 Rapid Diagnostic Test compared to qPCR assay for the diagnosis of onchocerciasis in high and low endemic settings of Ghana

This study evaluating the SD-Bioline Ov-16 Rapid Diagnostic Test against qPCR in Ghanaian communities reveals poor concordance between the two methods due to the RDT's detection of past exposure rather than active infection, highlighting the need for improved tools to accurately monitor onchocerciasis elimination progress.

Abena Akyeamaa Nyarko, Yvonne Ashong, Sarah-Sally Mawunyo Dogbe, Millicent Selassie Afatodzie, Grace Opoku Gyamfi, Kojo (…)2026-06-29
📄 medicine

The Role of Sugammadex for Neuromuscular Blockade Reversal in Neuro Critical Care Patients

This retrospective study of 153 adult nontraumatic neurocritical care patients demonstrates that sugammadex safely facilitates rapid neuromuscular blockade reversal, enabling timely neurologic assessments that directly influenced clinical decision-making in nearly half of the cases without causing neurologic deterioration.

Autumn McClung, Gianna Antinone, Michael Behal, Mary Massaro, Thomas Christianson, Paige Ledlow, Bryn Ferguson, Sarah Ku (…)2026-06-29